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This program supports partnerships and research that helps equip high school teachers to teach computer science, K-8 teachers to incorporate computer science and computational thinking in their classes, and school districts to create computing pathways across all grades.

Amount: $300,000 (Small RPP); $1,000,000 (Medium RPP); $2,000,000 (Large RPP)

Due Date: 02/11/2026

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Announcements Find Funding Large Grant Opportunities

This program aims to cultivate and grow the earliest foundations of convergent approaches for addressing a specific and compelling problem. Proposals should explore novel avenues not previously investigated that are at the forefront of advancing science through deep integration.

Amount: $1,200,000 (Phase I); $2,400,000 (Phase II)

Due Date: 02/09/2026

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Announcements Find Funding Large Grant Opportunities

The IUCRC program catalyzes breakthrough pre-competitive research by enabling close and sustained engagement between industry innovators, world-class academic teams, and government agencies.

Amount: Varies by type

Due Date: 09/1/2025 (Pre-Proposal)

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Announcements Find Funding Large Grant Opportunities

This is a multisector effort led by NSF in partnership with several industry and international agency partners, and other U.S. Federal agencies. The program seeks to support both fundamental research and verticals-driven technology development, demonstration, and translation activities that will lead to leaps in performance and capabilities of next generation advanced intelligent network systems that span the user-edge-core-cloud continuum.

Amount: $1,500,000 (Track 1); $6,000,000 (Track 2)

Due Date: 08/25/2025 (Track 1 Full Proposal; Track 2 Concept Outline); 09/25/2025 (Track 2 Full Proposal)

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Announcements Find Funding Large Grant Opportunities

This program supports archival projects that will significantly improve online public discovery and use of historical records collections. The program welcomes projects that engage the public, expand civic education, and promote understanding of the nation’s history, democracy, and culture from the founding era to the present day.

Amount: $150,000

Due Date: 08/15/2025 (Optional Draft); 11/05/2025 (Full Proposal)

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Announcements Find Funding Large Grant Opportunities

This program supports a broad range of hypothesis-driven, multidisciplinary studies that have a short-term goal of advancing the state of the science in melanoma research and/or patient care.

Amount: $2,265,000

Due Date: 06/30/2025 (Pre-Application); 10/01/2025 (Full Application)

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Announcements Find Funding Large Grant Opportunities

This program supports a multidisciplinary research program of at least two, but not more than three, distinct but complementary research projects addressing an overarching question relevant to rare melanomas.

Amount: $3,020,000

Due Date: 06/30/2025 (Pre-Application); 10/01/2025 (Full Application)

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Announcements Find Funding Large Grant Opportunities

This program funds Phase I and II patient-centered cancer clinical trials that have the potential to shift the paradigm for standard of care. The foundation strives to fund treatment-based studies at the bedside, including all types of cancers.  

Amount: $200,000 – $1,500,000

Due Date: 06/20/2025 (LOI)

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Announcements Find Funding Large Grant Opportunities

NSF: Expeditions in Computing (Expeditions)

This program provides the Computer and Information Science and Engineering (CISE) research and education community with the opportunity to pursue ambitious, fundamental research agendas that promise to define the future of computing and information.

Amount: $15,000,000

Due Date: 06/22/2026 (Pre-Proposals)

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Announcements Find Funding Large Grant Opportunities

This program supports non-incremental research designed to reduce risk of or prevent the development of Alzheimer’s disease and/or Alzheimer’s disease related dementias. Allowable research includes projects utilizing animal models as well as clinical research projects.

Amount: $1,000,000

Due Date: 06/12/2025 (Pre-Application); 08/29/2025 (Full Application)

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