The NIDCD invites applications for Clinical Research Center Grants designed to advance the diagnosis, prevention, treatment, and amelioration of human sensory and communication disorders. For this announcement, Clinical Research is defined as research involving individuals with a sensory and/or communication disorder, or data/tissues from individuals with a sensory and/or communication disorder.
Amount: $11,325,000
Due Date: 11/04/2025; 02/02/2026
This program supports research on the discovery and development of interventions to prevent and/or treat substance use disorders (SUDs) and overdose, including interventions to treat co-morbid SUDs. This includes preclinical and clinical research studies that will have high impact and quickly yield the necessary results to advance candidate interventions closer to regulatory approval or clinical adoption.
Amount: $22,650,000
Due Date: 10/20/2025; 02/20/2026
This program supports transitioning teams from research that is multidisciplinary to research that transcends disciplinary boundaries with novel conceptual frameworks, theories and methods. Proposals should explore novel avenues not previously investigated that are at the forefront of advancing science through deep integration.
Amount: $1,200,000 (Phase I); $2,400,000 (Phase II)
Due Date:Â 02/09/2026
This funding opportunity supports prospective or retrospective, efficient, and innovative natural history studies with a focus on collaborative and standardized approaches to ensure data quality and interpretability.
Amount: $1,600,000 (Prospective Studies); $300,000 (Retrospective Studies)
Due Date: 01/09/2026 (LOI); 02/10/2026 (Full Proposal)
This program supports interdisciplinary, collaborative, and highly synergistic projects that focus on the molecular understanding of human lupus and the heterogeneity of the disease. Successful teams will push the boundaries of innovation and bridge research and clinical efforts in lupus by using cutting-edge technologies to address critical questions that could bring about breakthroughs in lupus care, research, or drug development.
Amount: $3,000,000
Due Date: 09/30/2025 (LOI); 03/16/2026 (Invited Full Proposals)
This program supports partnerships and research that helps equip high school teachers to teach computer science, K-8 teachers to incorporate computer science and computational thinking in their classes, and school districts to create computing pathways across all grades.
Amount: $300,000 (Small RPP); $1,000,000 (Medium RPP); $2,000,000 (Large RPP)
Due Date: 02/11/2026
This program aims to cultivate and grow the earliest foundations of convergent approaches for addressing a specific and compelling problem. Proposals should explore novel avenues not previously investigated that are at the forefront of advancing science through deep integration.
Amount: $1,200,000 (Phase I); $2,400,000 (Phase II)
Due Date: 02/09/2026
NSF: Expeditions in Computing (Expeditions)
This program provides the Computer and Information Science and Engineering (CISE) research and education community with the opportunity to pursue ambitious, fundamental research agendas that promise to define the future of computing and information.
Amount: $15,000,000
Due Date: 06/22/2026 (Pre-Proposals)
This program aims to cultivate and grow the earliest foundations of convergent approaches for addressing a specific and compelling problem. Proposals should explore novel avenues not previously investigated that are at the forefront of advancing science through deep integration.
Amount: $1,200,000 (Phase I); $2,400,000 (Phase II)
Due Date: 02/09/2026
This program supports interdisciplinary research in e-mobility related topics along the electric vehicle/mobility value chain such as battery manufacturing and rare earth materials mining, supply chain and logistics, vehicle manufacturing, charging infrastructure and utilities, sales and consumer knowledge, and battery and EV components/materials recycling.
Amount: $40,000 up to $60,000 per award
Proposal due date: December 18, 2024 through InfoReady. Funds must be used by December 30, 2025.
