Research Insights

Large Grant Opportunities

Sign up for the large grant opportunities and limited submissions listserv. The Office of Research hosts a listserv that shares large funding opportunities and internal competition announcements weekly as well as a calendar of current limited submissions opportunities.

NSF: Synthesis Center for Molecular and Cellular Sciences (SCMCS) Monday, October 3, 2022 - Funds a Synthesis Center for Molecular and Cellular Sciences that will advance our ability to explain and predict complex molecular and cellular phenomena through innovative synthesis and integration of available biological data and related scientific knowledge. Amount: $20,000,000 Due Date: 01/13/2023 More information
NSF: Racial Equity in STEM Education Tuesday, September 27, 2022 - Supports bold, groundbreaking, and potentially transformative projects that contribute to advancing racial equity in STEM education and workforce development through practice and/or fundamental or applied research. Amount: $5,000,000 Due Date: 01/17/2023 More information
NIH: The NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-space Clinical Resource (ACR) (U24 Clinical Trial Not Allowed) Tuesday, September 27, 2022 - Funds the development, implementation, and maintenance of the AnVIL Clinical Resource (ACR), a suite of genomic-based clinical tools and services built into the NHGRI Data Science Analysis, Visualization, and Informatics Lab-Space (AnVIL) to foster clinical genomic research. Amount: $11,325,000 Due Date: 12/02/2022 More information
NEH: Dangers and Opportunities of Technology: Perspectives from the Humanities Tuesday, September 27, 2022 - Supports research that examines technology and its relationship to society through the lens of the humanities, particularly the role of technology in shaping current social and cultural issues. Amount: $1,500,000 Due Date: 02/02/2023 More information
NEH: National Digital Newspaper Program Tuesday, September 27, 2022 - This program aims to create a national digital resource of historically significant newspapers published between 1690 and 1963 from all 56 states and U.S. jurisdictions. Amount: $325,000  Deadline: Jan. 11,2023 More information
NIH: NIAID Investigator Initiated Program Project Applications Tuesday, September 27, 2022 - This Funding Opportunity Announcement (FOA) invites submission of investigator-initiated Program Project (P01) applications. The proposed programs should address scientific areas relevant to the NIAID mission. Amount: Budgets are not limited but need to reflect the actual needs of the project.  Deadline: Jan. 11,2023 More information
USDA Regional Food Business Centers Tuesday, September 27, 2022 - The centers will serve as the cornerstone of USDA’s development of local and regional supply chains. They will offer coordination, technical assistance, and capacity building support to small and mid-sized food and farm businesses, with the goal of creating a more resilient, diverse, and competitive food system. Amount: $15,000,000 – $50,000,000 Deadline: Nov. 22, 2022 […]
NIH: NIMH Biobehavioral Research Awards for Innovative New Scientists (NIMH BRAINS) Tuesday, September 13, 2022 - Supports the research and research career advancement of outstanding, exceptionally productive scientists who are in the early, formative stages of their careers.
NIH: Resource-Related Research Projects for Development of Animal Models and Related Materials (R24 Clinical Trials Not-Allowed) Tuesday, September 13, 2022 - Funds research aimed at developing, characterizing or improving animal models of human diseases.
NIH: Blood Brain Barrier Response to Antibodies Targeting Beta-Amyloid (R01 – Clinical Trial Not Allowed) Tuesday, September 13, 2022 - Funds research on cellular and molecular mechanisms that can be targeted to protect the blood-brain barrier.
NIH: BRAIN Initiative: Engineering and optimization of molecular technologies for functional dissection of neural circuits (UM1 Clinical Trial Not Allowed) Wednesday, September 7, 2022 - Funds research to develop molecular tools of high impact that are targetable to brain cell types for the monitoring and manipulation of neural circuits.
NIH: Maintaining Immunity after Immunization (U01 Clinical Trial Not Allowed) Wednesday, September 7, 2022 - Funds research to improve our understanding of how vaccines against infectious agents lead to durable protective immunity.
USDA: Sustainable Agriculture Research and Education Wednesday, September 7, 2022 - Funds research and outreach designed to increase knowledge concerning agricultural production systems.
NIH: The Metastasis Research Network (MetNet): MetNet Research Projects (U01 Clinical Trial Not Allowed) Wednesday, September 7, 2022 - Funds the Metastasis Research Network.
DOE: Funding Opportunity in Support of the Hydrogen Shot and a University Research Consortium on Grid Resilience Tuesday, August 30, 2022 - Funds a consortium focused on supporting the DOE Hydrogen Shot and a second EERE-wide topic area focused on grid resilience.
NIH: Laboratory of Developmental Biology (R24 Clinical Trial Not Allowed) Tuesday, August 30, 2022 - Supports an established research resource program to serve the biomedical research community aimed at the collection, identification, staging and distribution of conceptal tissues.
NSF: Advancing Informal STEM Learning (AISL) Wednesday, August 24, 2022 - Committed to funding research and practice, with continued focus on investigating a range of informal STEM learning (ISL) experiences and environments.
NIH: Maternal Health Research Centers of Excellence (U54 Clinical Trial Optional) Wednesday, August 24, 2022 - Funds an integrated multi-level approach encompassing structural, social and biobehavioral research strategies.
NEH: Digital Humanities Advancement Grants Wednesday, August 24, 2022 - Supports innovative, experimental and/or computationally challenging digital projects.
NIH: Contraceptive Development Research Center (P50 Clinical Trial Optional) Tuesday, August 9, 2022 - Supports multidisciplinary approaches towards the development of new and/or improved contraceptive methods for both men and women.
NIH: HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional) Tuesday, August 9, 2022 - Supports interdisciplinary research teams of multiple PDs/PIs to investigate the mechanism of action of pain relief by medical devices.
NSF Dynamic Language Infrastructure – NEH Documenting Endangered Languages Wednesday, July 27, 2022 - Supports projects to develop and advance knowledge concerning dynamic language infrastructure in the context of endangered human languages.
NIH: Understanding the Pathophysiology and Clinical Course of New-Onset Diabetes Following COVID-19 Wednesday, July 27, 2022 - Funds a study to establish a longitudinal cohort of individuals who developed diabetes following SARS-CoV-2 infection.
NIH: Stakeholder Engagement Innovation Center for Advancing Health Equity in Type 2 Diabetes Research (U2C – Clinical Trial Not Allowed) Wednesday, June 22, 2022 - Funds a novel national Stakeholder Engagement Innovation Center for advancing equity in type 2 diabetes research.
NIH: A Multi-omics Approach to Immune Responses in HIV Vaccination and Intervention (P01 Clinical Trial Not Allowed)  Tuesday, June 14, 2022 - The purpose of this FOA is to support multi-disciplinary, multi-component applications proposing the use of omics technologies to advance preventative and/or therapeutic vaccinations, and/or immunomodulatory cure interventions for HIV.
NIH: NINDS Interdisciplinary Team Science Grant (RM1) Thursday, May 26, 2022 - Funds an ambitious interdisciplinary team effort to tackle basic, translational and clinical research challenges within the mission of NINDS.
NEH: Public Humanities Projects Monday, May 16, 2022 - Supports projects that bring the ideas and insights of the humanities to life for general audiences.
NIH: BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs Wednesday, March 16, 2022 - Supports interdisciplinary teams to elucidate the contributions of dynamic circuit activity to a specific behavioral or neural system.
NSF Smart and Connected Communities (S&CC) Wednesday, December 8, 2021 - The S&CC program supports integrative research that addresses fundamental technological and social science dimensions of smart and connected communities and pilots solutions together with communities.
NSF: Biodiversity on a Changing Planet (BoCP) Thursday, October 21, 2021 - The Biodiversity on a Changing Planet program is a cross directorate and international program led by NSF that invites submission of interdisciplinary proposals addressing grand challenges in biodiversity science within the context of unprecedented environmental change.
CDC: Vector-Borne Disease Regional Centers of Excellence Thursday, October 21, 2021 - The purpose of this NOFO is to support research to improve national capacity to address the growing problem of vector-borne diseases via continued support for regional Centers of Excellence for Vector-Borne Diseases.
NSF: Harnessing the Data Revolution (HDR): Transdisciplinary Research in Principles of Data Science Phase II (TRIPODS) Monday, October 18, 2021 - NSF's Harnessing the Data Revolution Big Idea is a national-scale activity to enable new modes of data-driven discovery that will allow fundamental questions to be asked and answered at the frontiers of science and engineering.
NSF: Computer and Information Science and Engineering (CISE) Community Research Infrastructure Program Monday, October 18, 2021 - The Computer and Information Science and Engineering Community Research Infrastructure program drives discovery and learning in the core CISE disciplines by funding the creation and enhancement of world-class research infrastructure.
NIH: Development of Microbiome-Related Approaches for Diagnosis/Mitigation/Treatment of Radiation Injuries (U01 Clinical Trial Not Allowed) Monday, October 11, 2021 - The purpose of this FOA is to support research that will advance the understanding of how the microbiome affects radiation injury.
DOC: US Marine Life Observations: Coordinated Marine Biodiversity Observation Network (MBON) and Animal Telemetry Network (ATN) Activities to Ensure Resilient, Productive Ecosystems and Human Communities in the Face of Change Monday, October 11, 2021 - This program supports proposals that: (1) build upon the foundation established by MBON, ATN and the US IOOS Regional Associations to work across sectors and disciplines towards an integrated, sustained marine life observing capability for the U.S. ocean, coasts and Great Lakes, from estuaries to the deep ocean.
NIH: Systems Biology for Infectious Diseases (U19 Clinical Trial Not Allowed) Monday, October 11, 2021 - The purpose of the FOA is to support research that employs systems biology approaches to human pathogens.
NIH: SPARC Human Open Research Neural Engineering Technologies (HORNET) Initiative (U41) Monday, October 11, 2021 - This U41 opportunity will fund centers to create interoperable open-source modules that can be combined into custom profiles for new exploratory and clinical neuromodulation studies in the peripheral nervous system, and for potential applicability in the central nervous system.
NIH: Pediatric Obesity Discovery Science Research to Improve Understanding of Risk and Causal Mechanisms for Obesity in Early Life (R01) Monday, October 11, 2021 - The purpose of this FOA is to support innovative, discovery research studies to better characterize early-life risk factors and elucidate underlying causal mechanisms through which these risk factors contribute to the development of obesity during infancy and early childhood.
NSF: Integrative Research in Biology (IntBIO) Saturday, September 25, 2021 - This solicitation invites submission of collaborative proposals that tackle bold questions in biology and require an integrated approach to make substantive progress.
NSF: Cyberinfrastructure for Sustained Scientific Innovation (CSSI) Saturday, September 25, 2021 - This solicitation expands the Cyberinfrastructure for Sustained Scientific Innovation program by adding a new project class: Transition to Sustainability.
NSF: Biology Integration Institutes (BII) Tuesday, September 21, 2021 - The NSF Directorate for Biological Sciences program for Biology Integration Institutes (BII) supports diverse and collaborative teams of researchers investigating questions that span multiple disciplines within and beyond biology.
NSF: EHR Core Research – Resource Coordination Hub (ECR Hub) Monday, September 13, 2021 - NSF seeks proposals to create an EHR Core Research (ECR) Resource Coordination Hub (ECR Hub) that will be an intellectual partner to the ECR:Core and the ECR:BCSER grantee communities and the NSF to enhance the overall influence and reach of ECR STEM education research investments.
DOE: Natural Gas Demand Response Pilot Program Monday, September 13, 2021 - FOA soliciting cooperative agreements for the development of multiple regional natural gas demand response pilot programs in collaboration with utilities, local distribution companies and public utility commissions.
NEH: Digital Humanities Advancement Grants Monday, September 13, 2021 - computationally challenging digital projects, leading to work that can scale to enhance scholarly research, teaching and public programming in the humanities.
NSF: Facility and Instrumentation Request Process (FIRP) Monday, September 13, 2021 - The Facility and Instrumentation Request Process (FIRP) solicitation describes the mechanism by which the research community can propose projects that require access to instrumentation and facilities sponsored by the FARE Program.
NIH: National Cancer Institute Youth Enjoy Science Research Education Program (R25) Friday, September 3, 2021 - This funding opportunity seeks to facilitate the education of students from diverse backgrounds underrepresented in biomedical research who will become knowledgeable about cancer, and available to focus on cancer later in their careers.
NSF: Mathematical Sciences Research Institutes Tuesday, July 6, 2021 - The goals of the Mathematical Sciences Research Institutes program include advancing research in the mathematical sciences, increasing the impact of the mathematical sciences in other disciplines, and expanding the talent base engaged in mathematical research in the United States.
FY2021 Vannevar Bush Faculty Fellowship Friday, July 10, 2020 - This FOA seeks distinguished researchers for the purpose of conducting innovative basic research in areas of interest to the DoD and fostering long-term relationships between the VBFF Fellows and the DoD.
Tobacco Use and HIV in Low and Middle-Income Countries (U01 Clinical Trial Optional) Friday, July 10, 2020 - This FOA supports the development and evaluation of tobacco cessation interventions tailored to HIV-positive populations, including those with comorbidities such as tuberculosis (TB), in low-resource settings in low- and middle-income countries.
Limited Submission: Continuation of the Human Pancreas Analysis Program (HPAP) for Type 1 Diabetes (HPAP-T1D) (U01 Clinical Trial Not Allowed) Friday, July 10, 2020 - This FOA will support one team of investigators with combined expertise in human pancreas physiology and pathophysiology; collection, processing and multimodal analysis of human pancreatic tissues; and biological database building, curation and management.
Network of the National Library of Medicine Evaluation Center (U24) (Clinical Trial Not Allowed) Monday, July 6, 2020 - The NNLM Evaluation Center (NEC) will coordinate the assessment of the impact, efficacy and value of NNLM activities, services, and resources. A special focus will be placed on assessing community engagement and measuring its impact on persons who experience health disparities, and populations underrepresented in biomedical research.
Technical Assistance and Dissemination to Improve Services and Results for Children with Disabilities and Demonstration and Training Programs Monday, July 6, 2020 - The purpose of the program is to promote academic achievement and to improve results for children with disabilities by providing TA, supporting model demonstration projects, disseminating useful information, and implementing activities that are supported by scientifically based research.
Pediatric Biospecimen Procurement Center (BPC) Supporting the Developmental Gene Expression (dGTEx) Project (U24 Clinical Trial Not Allowed) Monday, July 6, 2020 - The purpose of this funding opportunity is for support of a Biospecimen Procurement Center (BPC) to enroll suitable pediatric donors and provide high quality tissue samples for analyses to the Laboratory, Data Analysis, and Coordinating Center.
Laboratory, Data Analysis, and Coordinating Center (LDACC) for the Developmental Genotype-Tissue Expression Project(U24) (Clinical Trial Not Allowed) Monday, July 6, 2020 - The LDACC will perform 2 major functions: a molecular laboratory to process tissue samples for sequencing and biobanking, and a data analysis and coordinating center to ensure coordination, monitor study progress and laboratory performance, perform basic analysis of data for gene expression analyses, and harmonize and submit datasets to be deposited in repositories such as the AnVIL (Analysis, Visualization, and Informatics Lab-space).
NIH: Hybrid Effectiveness-Implementation Trials for Heart, Lung, Blood, and Sleep Diseases in the Inpatient Setting (U01 – Clinical Trials Required) Friday, June 19, 2020 - This FOA supports hybrid effectiveness-implementation trials for heart, lung, blood, and sleep (HLBS) diseases in the inpatient setting and applications that propose a multidisciplinary research team that includes expertise in inpatient clinical research, implementation research, and biostatistics.