Research Insights
Large Grant Opportunities
The Office of Research hosts a listserv that shares large funding opportunities and internal limited submissions competition announcements weekly, in addition to maintaining a calendar of current limited submissions opportunities. Sign up for the Large Grant Opportunities and Limited Submissions listserv to receive weekly updates.
NSF: EDU Core Research (ECR:Core) Thursday, May 21, 2026 - This program supports research on STEM education in one or more of three research areas: STEM learning and learning environments, broadening participation in STEM, and STEM workforce development. Amount: $500,000 (Level I); $1,500,000 (Level II); $2,500,000 (Level III) Due Date: 10/01/2026 More information
NIH: HEAL INITIATIVE INTERACT Data Coordination and Integration Center (U24 Clinical Trial Not Allowed) Thursday, May 21, 2026 - This NOFO invites applications from eligible organizations to establish a Data Coordination and Integration Center (DCIC) which will support the coordination and integration of data from both the HEAL INTERACT program and progressively facilitate broader integration of related musculoskeletal datasets and programs. The Center will lead efforts for managing and integrating complex pain-associated data types and information […]
DoD: Peer Reviewed Medical, Technology/Therapeutic Development Award Tuesday, May 12, 2026 - This product-driven award mechanism intends to support the translation of promising preclinical findings into products for clinical applications, including prevention, detection, diagnosis, treatment, or quality of life, for a disease or condition related to one of the congressionally directed FY26 PRMRP topic areas and one of the FY26 PRMRP strategic goals. The program expects the […]
DoD: Peer Reviewed Medical, Lifestyle and Applied Health Research Award Tuesday, May 12, 2026 - This award supports clinical research and/or clinical trials using a combination of scientific disciplines including occupational science, psychology, psychometrics, biostatistics and epidemiology, surveillance, implementation science, and population health. Applications must address and provide a solution to one of the congressionally directed FY26 PRMRP topic areas and one of the FY26 PRMRP strategic goals. Amount: $4,200,000 […]
DoD: Peer Reviewed Medical Research Program Clinical Trial Award Tuesday, May 12, 2026 - This award supports the rapid implementation of clinical trials with the potential to have significant impact on the treatment and management of a disease or condition addressed in one of the congressionally directed FY26 PRMRP topic areas and FY26 PRMRP strategic goals. Amount: $800,000 (Planning); $6M (Level 1); $10M (Level 2); $20M (Level 3) Due […]
NIH: NIAID Investigator Initiated Program Project Applications (P01 Clinical Trial Not Allowed) Tuesday, May 12, 2026 - This NOFO invites applications which include at least two related, synergistic Research Projects that share a common central theme, focus, and/or overall objective; an Administrative Core; and optional Scientific Core(s). Applications must address scientific areas relevant to the NIAID mission. Amount: Unspecified Due Date: 09/26/2026 More information
DoW: Breast Cancer Research Program (BCRP) Breakthrough Award Level 4 Thursday, May 7, 2026 - The BCRP seeks to accelerate high-impact research with clinical relevance, encourage innovation and stimulate creativity, and facilitate productive collaborations. The intent of the Breakthrough Award is to support promising research with high potential to lead to or make breakthroughs in breast cancer. The FY26 Breakthrough Award mechanism contains four different funding levels designed to support […]
DoW: Breast Cancer Research Program Era of Hope Scholar Award Thursday, May 7, 2026 - This program supports individuals who are early in their careers with significant potential to effect meaningful change in breast cancer. Amount: $4,900,000 Due Date: 06/24/2026 (LOI); 07/08/2026 (Full Applications) More information
DoW: Peer Reviewed Cancer Clinical Trial Award Thursday, May 7, 2026 - This award supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of cancer within at least one of the FY26 PRCRP Topic Areas. Clinical trials proposed may evaluate promising new products, pharmacologic agents, devices, clinical guidance, and/or emerging approaches and technologies. Amount: $4,500,000 Due […]
NIH: Accelerating Product Excellence in Innovation and for Clinical Adoption (APEx) (U24 Clinical Trial Not Allowed) Thursday, May 7, 2026 - This program supports the formation of one Resource Center (RC) that will support promising strategies and products for tissue engineering and regenerative medicine (TE/RM). The RC will capitalize on their available clinical, scientific, industrial, regulatory, and commercialization expertise to select, support, and guide Interdisciplinary Translational Projects (ITPs) in the areas of therapeutics (including adult stem […]
NEH: Landmarks of American History and Culture and Summer Institutes Thursday, May 7, 2026 - The purpose of this program is to support humanities education through professional development for K-12 teachers and higher education faculty members. Amount: Up to $230,000 Due Date: 06/25/2026 More information
USDA NIFA: Specialty Crop Research Initiative Thursday, April 30, 2026 - This program’s purpose is to address the critical needs of the specialty crops industries by awarding grants to support research and extension that address key challenges of national, regional, and multi-state importance in sustaining all components of food and agriculture, including conventional and organic food production systems. Applicants are strongly encouraged to propose a unique […]
NEH Curriculum Development: Western Civilization Thursday, April 30, 2026 - This program supports formal education by strengthening the teaching and study of the humanities at institutions of higher education. For 2026, projects must be focused on Western civilization, American history, American government and civics, and/or the Great Books tradition. Amount: $750,000 Due Date: 06/25/2026 More Information
NIH: Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2024, 2025, and 2026 (P50 Clinical Trial Required) Monday, April 13, 2026 - This program will fund P50 SPORE grants to support state-of-the-art investigator-initiated translational research that will contribute to improved prevention, early detection, diagnosis, and treatment of an organ-specific cancer or a highly related group of cancers. For the purpose of this NOFO, a group of highly related cancers are those that are derived from the same […]
NEH: Media Projects Thursday, March 26, 2026 - The purpose of this program is to support the development, production, and distribution of radio programs, podcasts, and documentary films that engage general audiences with humanities ideas in creative and appealing ways. Amount: Up to $75,000 (Development); Up to $700,000 (Production) Due Date: 06/25/2026 More Information:
NEH: Collections Stewardship Thursday, March 19, 2026 - The goal of this program is to advance the preservation and availability of physical and digital collections important for research, teaching, and public engagement in the humanities. Amount: $50,000 – $500,000 Due Date: 05/11/2026; 12/15/2026 More Information:
Department of State: Advancing Global Health Tuesday, March 10, 2026 - The Department of State invites eligible applicants to advance the America First Global Health Strategy through its new Advancing Global Health (AGH) program, which aims to save lives, strengthen health systems, enhance efficiency, foster self-reliance, and ensure U.S. investments benefit American safety, strength, and prosperity. Amount: $500,000 – $250,000,000 Due Date: 05/31/2026 (Window 1); 11/14/2026 (Window 2); […]
NIH: Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Women, and Persons with Disabilities (UG3/UH3 – Clinical Trial Optional) Friday, February 27, 2026 - This program leverages the NICHD clinical research network infrastructure relevant to infants, children, women, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. Amount: $6,250,000 Due Date: 07/15/2026 More information
NSF: Mid-scale Research Infrastructure-1 (Mid-scale RI-1) Friday, February 27, 2026 - This program supports the design and implementation of research infrastructure — including equipment, cyberinfrastructure, large-scale datasets and personnel — whose total project costs are under $20 million. Amount: $4,000,000 – $19,999,999 Due Date: 09/01/2026 (Pre-Proposals); 02/08/2027 (Full Proposals) More information
NIH: National Centers for Cryo-electron Tomography (cryoET) (R24 -Clinical Trial Not Allowed) Thursday, February 12, 2026 - This Notice of Funding Opportunity (NOFO) is for support of National Centers for Cryoelectron Tomography (CryoET) to provide nationwide access to advanced cryoET instrumentation and technical support, and to assist investigators in acquiring the skills needed to perform cryoET studies. Amount: Unspecified Due Date: 01/26/2027 More Information:
Children’s Cancer Research Fund 2026 Accelerating Hope: Clinical Trials for Hard-to-Treat Cancers Award Thursday, February 5, 2026 - This grant mechanism provides support for clinical trials focused on hard-to-treat childhood cancers. Amount: $1,000,000 Due Date: 08/07/2026 (LOI); 11/16/2026 (Full Proposal) More Information:
NSF: Mathematical Foundations of Artificial Intelligence Monday, November 24, 2025 - This program supports research collaborations between mathematicians, statisticians, computer scientists, engineers and social behavior scientists to establish innovative and principled design and analysis approaches for AI technology. Amount: $500,000 – $1,500,000 Due Date: 10/09/2026 More Information
NSF: Expeditions in Computing (Expeditions) Friday, November 14, 2025 - This program supports long-term, multi-institutional research with the potential to transform computer and information science and engineering. Amount: Up to $15,000,000 Due Date: 06/22/2026 (Pre-Proposals) More Information
NSF: Expeditions in Computing (Expeditions) Thursday, May 8, 2025 - NSF: Expeditions in Computing (Expeditions) This program provides the Computer and Information Science and Engineering (CISE) research and education community with the opportunity to pursue ambitious, fundamental research agendas that promise to define the future of computing and information. Amount: $15,000,000 Due Date: 06/22/2026 (Pre-Proposals) More Information
NSF: Biodiversity on a Changing Planet (BoCP) Thursday, October 21, 2021 - The Biodiversity on a Changing Planet program is a cross directorate and international program led by NSF that invites submission of interdisciplinary proposals addressing grand challenges in biodiversity science within the context of unprecedented environmental change.
CDC: Vector-Borne Disease Regional Centers of Excellence Thursday, October 21, 2021 - The purpose of this NOFO is to support research to improve national capacity to address the growing problem of vector-borne diseases via continued support for regional Centers of Excellence for Vector-Borne Diseases.
NSF: Harnessing the Data Revolution (HDR): Transdisciplinary Research in Principles of Data Science Phase II (TRIPODS) Monday, October 18, 2021 - NSF's Harnessing the Data Revolution Big Idea is a national-scale activity to enable new modes of data-driven discovery that will allow fundamental questions to be asked and answered at the frontiers of science and engineering.
NSF: Computer and Information Science and Engineering (CISE) Community Research Infrastructure Program Monday, October 18, 2021 - The Computer and Information Science and Engineering Community Research Infrastructure program drives discovery and learning in the core CISE disciplines by funding the creation and enhancement of world-class research infrastructure.
NIH: Development of Microbiome-Related Approaches for Diagnosis/Mitigation/Treatment of Radiation Injuries (U01 Clinical Trial Not Allowed) Monday, October 11, 2021 - The purpose of this FOA is to support research that will advance the understanding of how the microbiome affects radiation injury.
DOC: US Marine Life Observations: Coordinated Marine Biodiversity Observation Network (MBON) and Animal Telemetry Network (ATN) Activities to Ensure Resilient, Productive Ecosystems and Human Communities in the Face of Change Monday, October 11, 2021 - This program supports proposals that: (1) build upon the foundation established by MBON, ATN and the US IOOS Regional Associations to work across sectors and disciplines towards an integrated, sustained marine life observing capability for the U.S. ocean, coasts and Great Lakes, from estuaries to the deep ocean.
NIH: Systems Biology for Infectious Diseases (U19 Clinical Trial Not Allowed) Monday, October 11, 2021 - The purpose of the FOA is to support research that employs systems biology approaches to human pathogens.
NIH: SPARC Human Open Research Neural Engineering Technologies (HORNET) Initiative (U41) Monday, October 11, 2021 - This U41 opportunity will fund centers to create interoperable open-source modules that can be combined into custom profiles for new exploratory and clinical neuromodulation studies in the peripheral nervous system, and for potential applicability in the central nervous system.
NIH: Pediatric Obesity Discovery Science Research to Improve Understanding of Risk and Causal Mechanisms for Obesity in Early Life (R01) Monday, October 11, 2021 - The purpose of this FOA is to support innovative, discovery research studies to better characterize early-life risk factors and elucidate underlying causal mechanisms through which these risk factors contribute to the development of obesity during infancy and early childhood.
NSF: Integrative Research in Biology (IntBIO) Saturday, September 25, 2021 - This solicitation invites submission of collaborative proposals that tackle bold questions in biology and require an integrated approach to make substantive progress.
NSF: Cyberinfrastructure for Sustained Scientific Innovation (CSSI) Saturday, September 25, 2021 - This solicitation expands the Cyberinfrastructure for Sustained Scientific Innovation program by adding a new project class: Transition to Sustainability.
NSF: Biology Integration Institutes (BII) Tuesday, September 21, 2021 - The NSF Directorate for Biological Sciences program for Biology Integration Institutes (BII) supports diverse and collaborative teams of researchers investigating questions that span multiple disciplines within and beyond biology.
NSF: EHR Core Research – Resource Coordination Hub (ECR Hub) Monday, September 13, 2021 - NSF seeks proposals to create an EHR Core Research (ECR) Resource Coordination Hub (ECR Hub) that will be an intellectual partner to the ECR:Core and the ECR:BCSER grantee communities and the NSF to enhance the overall influence and reach of ECR STEM education research investments.
DOE: Natural Gas Demand Response Pilot Program Monday, September 13, 2021 - FOA soliciting cooperative agreements for the development of multiple regional natural gas demand response pilot programs in collaboration with utilities, local distribution companies and public utility commissions.
NEH: Digital Humanities Advancement Grants Monday, September 13, 2021 - computationally challenging digital projects, leading to work that can scale to enhance scholarly research, teaching and public programming in the humanities.
NSF: Facility and Instrumentation Request Process (FIRP) Monday, September 13, 2021 - The Facility and Instrumentation Request Process (FIRP) solicitation describes the mechanism by which the research community can propose projects that require access to instrumentation and facilities sponsored by the FARE Program.
NIH: National Cancer Institute Youth Enjoy Science Research Education Program (R25) Friday, September 3, 2021 - This funding opportunity seeks to facilitate the education of students from diverse backgrounds underrepresented in biomedical research who will become knowledgeable about cancer, and available to focus on cancer later in their careers.
NSF: Mathematical Sciences Research Institutes Tuesday, July 6, 2021 - The goals of the Mathematical Sciences Research Institutes program include advancing research in the mathematical sciences, increasing the impact of the mathematical sciences in other disciplines, and expanding the talent base engaged in mathematical research in the United States.
FY2021 Vannevar Bush Faculty Fellowship Friday, July 10, 2020 - This FOA seeks distinguished researchers for the purpose of conducting innovative basic research in areas of interest to the DoD and fostering long-term relationships between the VBFF Fellows and the DoD.
Tobacco Use and HIV in Low and Middle-Income Countries (U01 Clinical Trial Optional) Friday, July 10, 2020 - This FOA supports the development and evaluation of tobacco cessation interventions tailored to HIV-positive populations, including those with comorbidities such as tuberculosis (TB), in low-resource settings in low- and middle-income countries.
Limited Submission: Continuation of the Human Pancreas Analysis Program (HPAP) for Type 1 Diabetes (HPAP-T1D) (U01 Clinical Trial Not Allowed) Friday, July 10, 2020 - This FOA will support one team of investigators with combined expertise in human pancreas physiology and pathophysiology; collection, processing and multimodal analysis of human pancreatic tissues; and biological database building, curation and management.
Network of the National Library of Medicine Evaluation Center (U24) (Clinical Trial Not Allowed) Monday, July 6, 2020 - The NNLM Evaluation Center (NEC) will coordinate the assessment of the impact, efficacy and value of NNLM activities, services, and resources. A special focus will be placed on assessing community engagement and measuring its impact on persons who experience health disparities, and populations underrepresented in biomedical research.
Technical Assistance and Dissemination to Improve Services and Results for Children with Disabilities and Demonstration and Training Programs Monday, July 6, 2020 - The purpose of the program is to promote academic achievement and to improve results for children with disabilities by providing TA, supporting model demonstration projects, disseminating useful information, and implementing activities that are supported by scientifically based research.
Pediatric Biospecimen Procurement Center (BPC) Supporting the Developmental Gene Expression (dGTEx) Project (U24 Clinical Trial Not Allowed) Monday, July 6, 2020 - The purpose of this funding opportunity is for support of a Biospecimen Procurement Center (BPC) to enroll suitable pediatric donors and provide high quality tissue samples for analyses to the Laboratory, Data Analysis, and Coordinating Center.
Laboratory, Data Analysis, and Coordinating Center (LDACC) for the Developmental Genotype-Tissue Expression Project(U24) (Clinical Trial Not Allowed) Monday, July 6, 2020 - The LDACC will perform 2 major functions: a molecular laboratory to process tissue samples for sequencing and biobanking, and a data analysis and coordinating center to ensure coordination, monitor study progress and laboratory performance, perform basic analysis of data for gene expression analyses, and harmonize and submit datasets to be deposited in repositories such as the AnVIL (Analysis, Visualization, and Informatics Lab-space).
NIH: Hybrid Effectiveness-Implementation Trials for Heart, Lung, Blood, and Sleep Diseases in the Inpatient Setting (U01 – Clinical Trials Required) Friday, June 19, 2020 - This FOA supports hybrid effectiveness-implementation trials for heart, lung, blood, and sleep (HLBS) diseases in the inpatient setting and applications that propose a multidisciplinary research team that includes expertise in inpatient clinical research, implementation research, and biostatistics.
NIH: NIDA Avant-Garde Award Program for HIV/AIDS and Substance Use Disorder Research (DP1, Clinical Trial Optional) Friday, June 5, 2020 - Supports exceptionally creative scientists, who propose high-impact research that will open new areas of HIV/AIDS research in the context of substance use disorders and/or lead to new avenues for prevention and treatment of HIV/AIDS in people who use drugs.
NIH: Regenerative Medicine Innovation Project (RMIP) Investigator-Initiated Clinical Trials (UG3/UH3 Clinical Trial Required) Friday, June 5, 2020 - Seeks meritorious clinical trials proposing to explore and enable the development of safe and effective regenerative medicine interventions using adult stem cells.
DoD Peer Reviewed Alzheimer’s, Accelerating Diagnostics for Traumatic Brain Injury Research Award Friday, May 22, 2020 - Supports high-impact, human-based development of robust diagnostic and/or prognostic biomarkers for chronic TBI as they pertain to AD/ADRD.
NSF: Discovery Research PreK-12 (DRK-12) Wednesday, May 13, 2020 - This program seeks to significantly enhance the learning and teaching of science, technology, engineering, mathematics and computer science by preK-12 students and teachers.
NIH: Coordinating Unit to Support the Kidney, Urology and Hematology (KUH) Innovative Science Accelerator Program (ISAC-CU) (U24 Clinical Trial Not Allowed) Friday, May 8, 2020 - The purpose of this FOA is to establish a Coordinating Unit to support the Kidney, Urology and Hematology Innovative Science Accelerator Program.