Research Insights
Large Grant Opportunities
Sign up for the large grant opportunities and limited submissions listserv. The Office of Research hosts a listserv that shares large funding opportunities and internal competition announcements weekly as well as a calendar of current limited submissions opportunities.
NSF: Discovery Research PreK-12 Program Resource Center on Transformative Education Research and Translation (DRK-12 RC) Friday, September 13, 2024 - This Center will be an intellectual partner as NSF seeks to enhance the overall influence and reach of the DRK-12 Program’s research and development investments. The DRK-12 RC will support and recruit diverse, multi-sector constituencies with the goal of achieving the field-, knowledge-, and partnership-building aims of the DRK-12 program. Amount: $5,000,000 Due Date: 02/28/2025 More Information
USDA: Specialty Crop Research Initiative Friday, September 13, 2024 - The purpose of this program is to support research and extension that address key challenges of national, regional, and multi-state importance in sustaining all components of food and agriculture, including conventional and organic food production systems. Amount: $10,000,000 Due Date: 11/08/2024 (Pre-Proposal) More Information
NEH: Digital Humanities Advancement Grants Friday, September 13, 2024 - This program supports work that is innovative, experimental, and contributes to the critical infrastructure that underpins scholarly research, teaching, and public programming in the humanities. Amount: Up to $350,000 Due Date: 01/09/2025 More Information
NSF Trailblazer Engineering Impact Award Wednesday, September 4, 2024 - This program supports individual investigators who propose novel research projects with the potential to innovatively and creatively address national needs and/or grand challenges, advance US leadership, and catalyze the convergence of engineering and science domains. Amount: $3,000,000 Due Date: 11/15/2024 (LOI); 01/14/2025 (Pre-Proposal) More Information
IMLS: 21st Century Museum Professionals Program Wednesday, August 28, 2024 - This program supports projects that offer professional development to the current museum workforce, train and recruit future museum professionals, and identify and share effective practices in museum workforce education and training. Amount: $100,000 – $500,000 Due Date: 11/15/2024 More Information
NSF: Mid-scale Research Infrastructure-1 (Mid-scale RI-1) Wednesday, August 28, 2024 - This program supports either design or implementation of unique and compelling Research Infrastructure projects. Mid-scale implementation projects may include any combination of equipment, instrumentation, cyberinfrastructure, broadly used large scale datasets and the personnel needed to successfully commission the project. Amount: $400,000 – $20M Due Date: 11/18/2024 (Pre-Proposal); 03/19/2025 (Invited Full Proposals) More Information
NIH: Optimization of Genome Editing Therapeutics for Alzheimer’s Disease-Related Dementias (ADRD) (U01 – Clinical Trials Not Allowed) Wednesday, August 21, 2024 - This program supports the optimization of promising genome editing-based therapeutic leads for Alzheimer’s Disease-Related Dementias, by advancing therapeutic candidates towards IND-enabling studies Amount: $7,550,000 Due Date: 11/19/2024 More Information
IMLS: National Leadership Grants for Museums Wednesday, August 21, 2024 - This program supports projects that address critical needs of the museum field and that have the potential to advance practice in the profession to strengthen museum services for the American public. Amount: $50,000 – $750,000 Due Date: 11/15/2024 More Information
NSF: Regional Resilience Innovation Incubator Wednesday, August 21, 2024 - This program supports community-engaged team science to co-design high-impact solutions to climate-related societal challenges that leverage recent advances in fundamental climate change and Earth system science research. Amount: $500,000 (Phase 1); $15,000,000 (Phase 2) Due Date: 12/16/2024 (LOI); 01/16/2025 (Full Proposal) More Information
NEH: Scholarly Editions and Translations Tuesday, August 13, 2024 - This program supports collaborative teams who are editing, annotating, and translating foundational humanities texts that are vital to generating new scholarships but are inaccessible or only available in inadequate editions or translations. Amount: $300,000 Due Date: 09/30/2024 (Optional Draft);12/04/2024 (Full Proposal) More information
NIH: Tissue Chips in Space 2.0: Translational Multi-Organ Tissue Chip Systems for Drug Efficacy, Toxicity Testing, and Personalized Medicine in Human Health, Aging and Associated Diseases (UG3/UH3 Clinical Trial Not Allowed) Wednesday, July 31, 2024 - This program’s purpose is to develop multi-organ automated microphysiological systems for studying the effects of microgravity conditions on human body in low Earth orbit at the International Space Station National Laboratory. Amount: $5,662,500 Due Date: 09/16/2024 (LOI); 10/18/2024 (Full Proposal) More information
NIH: RNA Modifications Driving Oncogenesis (RNAMoDO; U01 Clinical Trial Not Allowed) Wednesday, July 31, 2024 - This initiative promotes fundamental studies in the emerging area of RNA modifications that underlie the oncogenic process, focusing on the central role of RNA modifications in translational reprogramming of cancer cells. Amount: $4,907,500 Due Date: 10/05/2024 (LOI); 11/04/2024 (Full Proposal) More information
NIH: Revolutionizing Innovative, Visionary Environmental Health Research (RIVER) (R35 Clinical Trial Optional) Wednesday, July 31, 2024 - This program supports outstanding investigators in the Environmental Health Sciences, giving them intellectual and administrative freedom, as well as sustained support to pursue their research in novel directions in order to achieve greater impacts. Amount: $7,248,000 Due Date: 10/01/2024 (LOI); 11/01/2024 (Full Proposal) More information
NIH: Translating Socioenvironmental Influences on Neurocognitive Development and Addiction Risk (TranSINDA) (U24 Clinical Trial Not Allowed) Wednesday, July 24, 2024 - This program invites applications for a Data Coordination Center (DCC) to serve as the organizational hub for the management and sharing of TranSINDA data, establish a modern data ecosystem that integrates TranSINDA data into appropriate data repositories under common data standards and serves as a resource for software tools for large scale data query, analysis, […]
NIH: Halting Tuberculosis (TB) Transmission (R01 Clinical Trial Optional) Wednesday, July 24, 2024 - This program aims to understand the critical drivers of tuberculosis (TB) transmission; develop effective methods to measure rates of TB transmission; and assess potential interventions to prevent TB transmission and detect infectious TB. Amount: $5,662,500 Due Date: 11/04/2024 (LOI); 12/04/2024 (Full Proposal) More information
NSF: Cyberinfrastructure for Sustained Scientific Innovation (CSSI) Friday, July 19, 2024 - This program enables science and engineering research and education by developing, creating, and supporting secure, advanced, scalable, and global research cyberinfrastructure (CI). The program emphasizes integrated CI services, quantitative metrics with targets for delivery and usage of these services, and community creation, and encourages broad, interdisciplinary proposals. Amount: $600,000 (Elements); $600,001 – $5,000,000 (Framework Implementations) […]
NSF: Computer and Information Science and Engineering (CISE): Core Programs, Large Projects Wednesday, July 10, 2024 - This solicitation invites proposals on bold new scientific ideas tackling ambitious fundamental research problems that cross the boundaries of two or more CISE core programs, which range from Computing and Communications to Computer and Network Systems, to Information and Intelligence Systems. Amount: $3,000,000 – $5,000,000 Due Date: 09/29/2025 More information
NIH: Translational Resource Centers to Build Bridges Between Substance Use Epidemiology/Etiology and Prevention Intervention Research (U24 Clinical Trials Not Allowed) Wednesday, July 10, 2024 - This program seeks innovative applications for Translational Resource Centers that will establish and support multidisciplinary research teams to conduct translational research between the fields of 1) substance use epidemiology and etiology and 2) substance use prevention intervention. Amount: $2,114,000 Deadline: 10/13/2024 (LOI);11/13/2024 (Full Proposal) More information
NIH: Individually Measured Phenotypes to Advance Computational Translation in Mental Health (IMPACT-MH) (U01 Clinical Trial Optional) Monday, July 1, 2024 - This program aims to stimulate and support research that will use behavioral measures and computational methods to define novel clinical signatures that can be used for individual-level prediction and clinical decision making in mental disorders. Amount: $18,875,000 Due Date: 09/18/2024 (LOI); 10/18/2024 (Full Proposal) More information
NIH: Alzheimer’s Drug-Development Program (U01 Clinical Trial Optional) Thursday, June 27, 2024 - This program invites applications proposing pre-clinical and early stage clinical (Phase I) development of novel small-molecule and biologic drug candidates that aim to prevent Alzheimer’s disease (AD), slow its progression, or treat its cognitive and behavioral symptoms. Amount: $11,325,000 Due Date: 02/05/2025 More information
NEH: Archaeological and Ethnographic Field Research Thursday, June 27, 2024 - This program provides funding for empirical research that answers significant humanities questions through archaeological and/or ethnographic methods. Amount: $150,000 Due Date: 07/15/2024 (Optional Draft); 09/25/2024 (Full Proposal) More information
NIH: Whole Person Research and Coordination Center (Whole Person RCC) U24 (Clinical Trial Not Allowed) Thursday, June 20, 2024 - This center will be integral in coordinating the initial and future research programs in whole person health research, with the goal of seamlessly integrating current and emerging biomedical knowledge about human health and forming a comprehensive, multi-scale human knowledge network. Amount: $11,325,000 Due Date: 10/01/2024 (LOI); 11/01/2024 (Invited Full Proposals) More information
DoD: Peer Reviewed Cancer Convergent Science Cancer Consortium Award Thursday, June 20, 2024 - This program’s goal is to improve mission readiness and quality of life by decreasing the burden of cancer on Service Members, their Families, Veterans, and the American public. Amount: $20,000,000 Due Date: 07/24/2024 (LOI); 10/15/2024 (Full Proposal) More information
Research Collaboration Network in Structural Racism Measurement and Modeling (U24 Clinical Trial Optional) Thursday, June 20, 2024 - This program invites applications to form an interdisciplinary network of scholars from a variety of disciplines to collaborate with each other in the measurement and modeling of structural racism to facilitate research on life course health and aging. Amount: $7,550,000 Due Date: 09/17/2024 (LOI); 10/17/2024 (Full Proposal) More information
NIH: Translational Resource Centers to Build Bridges Between Substance Use Epidemiology/Etiology and Prevention Intervention Research (U24 Clinical Trials Not Allowed) Thursday, June 13, 2024 - This program seeks innovative applications for Translational Resource Centers that will establish and support multidisciplinary research teams to conduct translational research between the fields of 1) substance use epidemiology and etiology and 2) substance use prevention intervention. Amount: $2,114,000 Due Date: 10/13/2024 More information
NSF: Computer and Information Science and Engineering (CISE): Core Programs, Large Projects Wednesday, June 12, 2024 - This solicitation invites proposals on bold new scientific ideas tackling ambitious fundamental research problems that cross the boundaries of two or more CISE core programs, which range from Computing and Communications to Computer and Network Systems, to Information and Intelligence Systems. Amount: $3,000,000 – $5,000,000 Due Date: 09/29/2025 More information
NSF: Accelerating Computing-Enabled Scientific Discovery (ACED) – Discovery Proposals Wednesday, June 12, 2024 - This program seeks to harness computing to accelerate scientific discovery, while driving new computing advancements. Amount: $3,000,000 Due Date: 01/14/2025 More information
DOE: Predictive Science Academic Alliance Program IV Wednesday, June 5, 2024 - This program’s goal is to engage the U.S. academic community in advancing science-based modeling and simulation technologies. This iteration adds a focus on the development and application of artificial intelligence (AI) and machine learning (ML) technologies to improve quantified predictive capabilities. Amount: $7,500,000 – $17,500,000 Due Date: 09/30/2024 More information
National Archives and Records Administration: Archival Projects Wednesday, June 5, 2024 - This program supports archival projects that significantly improve online public discovery and use of historical records collections. Amount: $150,000 Due Date: 08/15/2024 (Optional Draft); 11/07/2024 (Full Proposal) More information
NEH: Dialogues on the Experience of War Wednesday, June 5, 2024 - This program supports the development of humanities-focused discussion programs that enlarge the understanding of the meaning and experiences of military service and war. Amount: $100,000 Due Date: 08/01/2024 (Optional Draft); 09/17/2024 (Full Proposal) More information
NSF: Gen-4 Engineering Research Centers Wednesday, June 5, 2024 - This program aims to integrate engineering research and education with technological innovation to transform and improve national prosperity, health, and security. The program supports convergent research that will lead to strong societal impact. Amount: $26,000,000 Due Date: 09/03/2024 (LOI); 09/30/2024 (Pre-Proposal) More information
Alzheimer’s Drug Discovery Foundation: Prevention RFP Tuesday, May 21, 2024 - This program supports studies of cognitive symptoms due to health conditions, comparative effectiveness research, and epidemiological studies that probe whether the use or choice of drugs alters the risk for dementia or cognitive decline. Amount: $5,000,000 Due Date: 09/30/2024 (LOI); 12/09/2024 (Full Proposal) More information
Alzheimer’s Drug Discovery Foundation: Drug Development RFP Tuesday, May 21, 2024 - This program supports investigational new drug-enabling studies and early-phase clinical trials that test promising pharmacological interventions and devices for Alzheimer’s disease and related dementias. Amount: $5,000,000 Due Date: 09/30/2024 (LOI); 12/09/2024 (Full Proposal) More information
NSF: Molecular Foundations for Sustainability: Sustainable Polymers Enabled by Emerging Data Analytics (MFS-SPEED) Tuesday, May 21, 2024 - This program’s goal is to support fundamental research enabling the accelerated discovery and ultimate manufacturing of sustainable polymers using state-of-the-art data science, and to enhance development of a cross-disciplinary workforce skilled in this area. Amount: $2,000,000 Due Date: 01/16/2025 More information
NIH: Precision Mental Health: Develop Tools to Inform Treatment Selection in Depression (UG3/UH3 Clinical Trial Optional) Monday, April 15, 2024 - The purpose is to create a pipeline to accelerate the development and early validation of predictive tools and/or biomarkers to inform individual-level treatment selection among two or more existing therapeutics for depression. Amount: $12,835,000 Due Date: 09/18/2024 (LOI); 10/18/2024 (Full Proposal) More Information
NIH: Specialized Programs of Research Excellence (SPOREs) in Cancer Health Disparities and Minority Health (CHD-MH) (U54 Clinical Trial Optional) Wednesday, April 3, 2024 - This program will fund a network of multidisciplinary, multi-institutional SPOREs uniquely focused on health disparities and/or minority health translational research for improved prevention, early detection, diagnosis, and treatment of cancer in populations who are underserved and/or underrepresented. Amount: $12,080,000 Due Date: 08/26/2024 (LOI); 09/26/2024 (Full Proposal) More Information
NIH: Building Interdisciplinary Research Careers in Women’s Health (BIRCWH) (K12 Clinical Trial Optional) Monday, March 18, 2024 - This program supports mentored research career development of junior faculty members who have recently completed clinical training or postdoctoral fellowships, and who will be engaged in interdisciplinary basic, translational, data science, behavioral, clinical, and/or health services research relevant to the health of women and, where appropriate, the use of both sexes to better understand the […]
NSF: Ideas Lab: Advancing Cell-Free Systems Toward Increased Range of Use-Inspired Applications Monday, March 18, 2024 - This initiative will accelerate the adoption of cell-free systems, enable new applications of this technology and contribute to the growth of the U.S. bioeconomy. Amount: $11,250,000 Due Date: 05/17/2024 (Preliminary Proposal); 09/20/2024 (Full Proposal) More Information
NSF: Ideas Lab: Breaking the Low Latency Barrier for Verticals in Next-G Wireless Networks Monday, February 26, 2024 - The vision of this program is to support R&D that will dramatically reduce the E2E latencies cost-effectively to spur a great number of emerging vertical industries that will transform the way we live and interact with each other. Amount: $7,400,000 Due Date: 04/18/2024 (Preliminary Proposals); 09/30/2024 (Full Proposals) More Information
NIH: Centers of Excellence for Translational Research (CETR) (U19 Clinical Trial Not Allowed) Wednesday, December 20, 2023 - This program will support multidisciplinary translational research Centers focused on generating, validating, and advancing medical countermeasures against bacteria or fungi listed in the NOFO with known and emerging resistance to current therapies. Amount: $37,750,000 Due Date: 03/29/2024 (LOI);04/30/2024 (Full Proposal) More information
NIH: Individually Measured Phenotypes to Advance Computational Translation in Mental Health Wednesday, May 10, 2023 - Supports the work of the research projects funded under the Individually Measured Phenotypes to Advance Computational Translation in Mental Health (IMPACT-MH) initiative described in the companion announcement RFA-MH-23-105. Amount: $18,875,000 Due Date: 6/14/23 More Information
NEH: Digital Projects for the Public Wednesday, March 22, 2023 - This program supports projects that interpret and analyze humanities content in primarily digital platforms and formats, such as websites, mobile applications and tours, interactive touch screens and kiosks, games, and virtual environments. Amount: $400,000 Due Date: 6/14/23 More Information
NIH: Development of Novel Nonsteroidal Contraceptive Methods Tuesday, October 18, 2022 - Supports multidisciplinary research approaches for the development of novel nonsteroidal contraceptive products for men and women that act prior to fertilization. Amount: $3,020,000 Due Date: 3/29/23 More information
NIH: BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs Wednesday, March 16, 2022 - Supports interdisciplinary teams to elucidate the contributions of dynamic circuit activity to a specific behavioral or neural system.
NSF: Biodiversity on a Changing Planet (BoCP) Thursday, October 21, 2021 - The Biodiversity on a Changing Planet program is a cross directorate and international program led by NSF that invites submission of interdisciplinary proposals addressing grand challenges in biodiversity science within the context of unprecedented environmental change.
CDC: Vector-Borne Disease Regional Centers of Excellence Thursday, October 21, 2021 - The purpose of this NOFO is to support research to improve national capacity to address the growing problem of vector-borne diseases via continued support for regional Centers of Excellence for Vector-Borne Diseases.
NSF: Harnessing the Data Revolution (HDR): Transdisciplinary Research in Principles of Data Science Phase II (TRIPODS) Monday, October 18, 2021 - NSF's Harnessing the Data Revolution Big Idea is a national-scale activity to enable new modes of data-driven discovery that will allow fundamental questions to be asked and answered at the frontiers of science and engineering.
NSF: Computer and Information Science and Engineering (CISE) Community Research Infrastructure Program Monday, October 18, 2021 - The Computer and Information Science and Engineering Community Research Infrastructure program drives discovery and learning in the core CISE disciplines by funding the creation and enhancement of world-class research infrastructure.
NIH: Development of Microbiome-Related Approaches for Diagnosis/Mitigation/Treatment of Radiation Injuries (U01 Clinical Trial Not Allowed) Monday, October 11, 2021 - The purpose of this FOA is to support research that will advance the understanding of how the microbiome affects radiation injury.
DOC: US Marine Life Observations: Coordinated Marine Biodiversity Observation Network (MBON) and Animal Telemetry Network (ATN) Activities to Ensure Resilient, Productive Ecosystems and Human Communities in the Face of Change Monday, October 11, 2021 - This program supports proposals that: (1) build upon the foundation established by MBON, ATN and the US IOOS Regional Associations to work across sectors and disciplines towards an integrated, sustained marine life observing capability for the U.S. ocean, coasts and Great Lakes, from estuaries to the deep ocean.
NIH: Systems Biology for Infectious Diseases (U19 Clinical Trial Not Allowed) Monday, October 11, 2021 - The purpose of the FOA is to support research that employs systems biology approaches to human pathogens.
NIH: SPARC Human Open Research Neural Engineering Technologies (HORNET) Initiative (U41) Monday, October 11, 2021 - This U41 opportunity will fund centers to create interoperable open-source modules that can be combined into custom profiles for new exploratory and clinical neuromodulation studies in the peripheral nervous system, and for potential applicability in the central nervous system.
NIH: Pediatric Obesity Discovery Science Research to Improve Understanding of Risk and Causal Mechanisms for Obesity in Early Life (R01) Monday, October 11, 2021 - The purpose of this FOA is to support innovative, discovery research studies to better characterize early-life risk factors and elucidate underlying causal mechanisms through which these risk factors contribute to the development of obesity during infancy and early childhood.
NSF: Integrative Research in Biology (IntBIO) Saturday, September 25, 2021 - This solicitation invites submission of collaborative proposals that tackle bold questions in biology and require an integrated approach to make substantive progress.
NSF: Cyberinfrastructure for Sustained Scientific Innovation (CSSI) Saturday, September 25, 2021 - This solicitation expands the Cyberinfrastructure for Sustained Scientific Innovation program by adding a new project class: Transition to Sustainability.