Research Insights

Large Grant Opportunities

Sign up for the large grant opportunities and limited submissions listserv. The Office of Research hosts a listserv that shares large funding opportunities and internal competition announcements weekly as well as a calendar of current limited submissions opportunities.

NEH: Humanities Connections Wednesday, May 31, 2023 - Seeks to expand the role of the humanities in undergraduate education at two- and four-year institutions by encouraging partnerships between humanities faculty and their counterparts in other areas of study. Amount: $150,000 Due Date: 9/7/23 More Information
NIH: Comprehensive Alcohol Research Centers Wednesday, May 31, 2023 - Seeks to fund an integrated, broad-based multidisciplinary, multi-investigator, long-term program of research and research support activities planned around a specific major research theme. Amount: $9,437,500 Due Date: 11/15/23 More Information
NIH: Assessment of TBI-related ADRD Pathology Related to Cognitive Impairment and Dementia Outcomes  Wednesday, May 31, 2023 - Invites applications for a multisite study to comprehensively characterize ADRD relevant pathology related to cognitive impairment and dementia outcomes in persons with a history of traumatic brain injury (TBI). Amount: $9,815,000 Due Date: 7/28/23 More Information
NIH: Specialized Alcohol Research Centers Wednesday, May 31, 2023 - Invites applications for specialized Alcohol Research Centers using the P50 mechanism. Amount: $8,682,500 Due Date: 11/15/23 More Information
NSF: Community Infrastructure for Research in Computer and Information Science and Engineering Wednesday, May 24, 2023 - Funds the creation and enhancement of world-class research infrastructure that develops accompanying user services and engagement needed to attract, nurture, and grow a robust research community. Amount: $5,000,000 Due Date: 9/8/23 More Information
NIH: Bioinformatics Resource Center (BRC) Wednesday, May 24, 2023 - The BRC Program will address bioinformatics needs in the research community to accelerate the development of diagnosis, prevention, and treatment of infectious diseases. Amount: $36,240,000 Due Date: 8/25/23 More Information
NIH: Analyzing Early Events in TB and TB/HIV Infection for Interventional Targets  Wednesday, May 24, 2023 - The purpose of this program is to support mechanistic studies of the early stage of Mycobacterium tuberculosis (Mtb) infection, with and without HIV, to identify interventional targets for vaccine and host-directed therapies. Amount: $5,033,333 Due Date: 10/11/23 More Information
NIH: Collaborative Opportunities for Multidisciplinary, Bold, and Innovative Neuroscience (COMBINE) Wednesday, May 24, 2023 - Aims to integrate the efforts of three to six PDs/PIs to pursue a bold, impactful, and challenging goal with defined 5-year outcomes within the scope of this program and the NINDS mission. Amount: $11,325,000 Due Date: 10/20/23 More Information
NEH: Public Humanities Projects Wednesday, May 17, 2023 - Funds projects that bring the ideas of the humanities to life for general audiences through public programming. Projects must engage humanities scholarship to analyze significant themes in disciplines such as history, literature, ethics, and art history and reach broad and diverse public audiences in non-classroom settings. Amount: $1,000,000 Due Date: 8/9/23 More Information
NEH: Climate Smart Humanities Organizations Wednesday, May 17, 2023 - Supports comprehensive assessment and strategic planning efforts by humanities organizations to mitigate physical and operational environmental impacts and adapt to a changing climate. Projects will result in climate action and adaptation planning documents or similar detailed assessments including prioritized, measurable actions and their expected outcomes. Amount: $300,000 Due Date: 9/14/23 More Information
NSF: Robert Noyce Teacher Scholarship Program Wednesday, May 17, 2023 - Invites innovative proposals that address the critical need for recruiting, preparing, and retaining highly effective elementary and secondary mathematics and science teachers and teacher leaders who persist as classroom teachers in high-need Local Education Agencies (LEA), (a.k.a. high-need school district). Amount: $3,250,000 Due Date: 8/29/23 More Information
NSF: Research Training Groups in the Mathematical Sciences Wednesday, May 10, 2023 - Aims to strengthen the nation’s scientific competitiveness by increasing the number of well-prepared U.S. citizens, nationals, and permanent residents who pursue careers in the mathematical sciences, be they in academia, government, or industry. Amount: $2,500,000 Due Date: 8/8/23 More Information
NIH: NINDS Sustainable Transformation of Institutional Research Rigor Wednesday, May 10, 2023 - Seeks proposals for programs that enhance research rigor and transparency practices within academic and research institutions to promote a culture of high-quality neuroscience research. Amount: $3,624,000 Due Date: 10/17/23 More Information
NIH: Individually Measured Phenotypes to Advance Computational Translation in Mental Health Wednesday, May 10, 2023 - Supports the work of the research projects funded under the Individually Measured Phenotypes to Advance Computational Translation in Mental Health (IMPACT-MH) initiative described in the companion announcement RFA-MH-23-105. Amount: $18,875,000 Due Date: 6/14/23 More Information
NEH: Media Projects Wednesday, May 10, 2023 - Supports the development, production, and distribution of radio programs, podcasts, documentary films, and documentary film series that engage general audiences with humanities ideas in creative and appealing ways. Amount: $1,000,000 Due Date: 8/9/23 More Information
NIH: HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices Wednesday, May 3, 2023 - Supports the development of safe and effective devices to treat pain with little or no addiction liability with the overall goal of optimizing therapeutic outcomes for these technologies. Amount: $11,325,000 Due Date: 6/13/23 More Information
NIH: Cancer Immunoprevention Network (CIP-Net) Research Projects Wednesday, April 26, 2023 - Invites proposals that develop a deeper understanding of basic mechanisms of immunoprevention, discover novel immunoprevention strategies, and foster a community of cancer immunoprevention researchers. Amount: $3,775,000 Due Date: 7/3/23 More Information
NSF: Centers for Chemical Innovation Wednesday, April 19, 2023 - Supports research centers focused on major, long-term fundamental chemical research challenges. CCIs that address these challenges will produce transformative research, lead to innovation, and attract broad scientific and public interest. Amount: $4,000,000 Due Date: 8/10/23 (preliminary proposal); 10/18/23 (full proposal) More Information
NIH: Centers of Excellence in Genomic Science (RM1 Clinical Trial Optional) Wednesday, April 19, 2023 - Establishes academic Centers for advanced genome research. Each CEGS award supports a multi-investigator, interdisciplinary team to develop integrated, transformative genomic approaches to address a biomedical problem. Amount: $15,855,000 Due Date: 6/23/23 More Information
NIH: Integration and Coordination Center (ICC) Wednesday, April 5, 2023 - The purpose of this FOA is to invite applications for an Integration and Coordination Center (ICC) for the Common Fund Data Ecosystem (CFDE) that will help build internal cohesion within the program. Amount: $14,345,000 Due Date: 6/28/23 More Information
NSF: Centers for Research and Innovation in Science, the Environment and Society (CRISES) Wednesday, April 5, 2023 - Seeks to build research capacity and infrastructure to address complex and compounding crises whose solutions require a human-centered approach to help generate effective and long-lasting solutions that benefit the entire U.S. public. Amount: Varies Due Date: 6/26/23 More Information
NSF: Mid-scale Research Infrastructure-2 Wednesday, April 5, 2023 - Seeks to implement unique and compelling Research Infrastructure projects that may include any combination of equipment, instrumentation, cyberinfrastructure, broadly used large-scale data sets, and commissioning and/or personnel. Amount: $20,000,000 – $99,999,999 Due Date: 5/15/23 (LOI); 6/20/23 (Preliminary Proposal); 12/18/23 (full proposal) More Information
NEH: Humanities Collections and Reference Resources Wednesday, March 29, 2023 - Supports projects that extend the reach of humanities collections and make their intellectual content widely accessible or create resources that facilitate the use of cultural materials for basic information or in-depth investigation.  Amount: $350,000 Due Date: 7/18/23 More Information
NSF: Synthesis Center for Understanding Organismal Resilience Wednesday, March 29, 2023 - Brings together communities that leverage existing data to catalyze discoveries through synthesis, analysis, and integrative training focusing on organisms as integrated units of biological organization i.e., why they are structured as they are and function as they do. Amount: $20,000,000 Due Date: 1/12/24 (preliminary proposal), 7/15/24 (full proposal) More Information
NIH: NIDA Avant-Garde Program for HIV and Substance Use Disorder Research Wednesday, March 29, 2023 - Supports exceptionally creative scientists, who propose high-impact studies that open new areas of HIV research in the context of substance use and Substance Use Disorders (SUD) and/or lead to new avenues for prevention and treatment of HIV in people with SUD. Amount: $5,285,000 Due Date: 8/15/23 More Information
NEH: Digital Projects for the Public Wednesday, March 22, 2023 - This program supports projects that interpret and analyze humanities content in primarily digital platforms and formats, such as websites, mobile applications and tours, interactive touch screens and kiosks, games, and virtual environments. Amount: $400,000 Due Date: 6/14/23 More Information
NIH: BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System Wednesday, March 22, 2023 - This FOA seeks applications for proof-of-concept testing and development of new technologies and novel approaches for recording and modulation of neural cells and circuits, to address major challenges and enable transformative understanding of dynamic signaling in the central nervous system. Amount: $3,020,000 Due Date: 6/30/23 More Information
NIH: National Centers for Cryoelectron Microscopy Wednesday, March 15, 2023 - This initiative will support national service centers for molecular structure determination by high resolution cryoelectron microscopy (cryoEM).  Amount: $49,075,000 Due Date: 6/30/23 More Information
NIH: Research Network to Promote Multidisciplinary Mechanistic and Translational Studies of Sickle Cell Disease Pain (U24, Clinical Trial Optional) Wednesday, March 8, 2023 - Funds a Research Network that promotes multidisciplinary mechanistic and translational studies of Sickle Cell Disease (SCD) pain to develop compelling research frameworks and models to study SCD pain that will support interdisciplinary collaborations. Amount: $4,530,000 Due Date: 10/1/23 More information
NIH: Exploratory Grants for Climate Change and Health Research Center Development Wednesday, March 8, 2023 - Solicits P20 planning grant applications to sustain a program of fundamental and applied research that examines the impacts of climate change on health and to develop action-oriented solutions to protect the health of individuals, communities, and nations from the hazards posed by climate change.  Amount: $3,850,500 Due Date: 11/7/23 More information
NIH: Networking/Infrastructure Project for Research on Determinants of Differences Among Human and Nonhuman Primate Species in Life Spans, Life Histories, and Other Aging Related Outcomes, and Prospects for Translation Wednesday, February 22, 2023 - Solicits R61/R33 applications proposing to establish and conduct a networking and infrastructure project to enhance the development of comparative research on determinants of differences among human and nonhuman primate life spans, life histories, and other aging-related outcomes, and prospects for translating findings from this research into development of human interventions.  Amount: $5,889,000 Due Date: 9/27/23 More Information
NIH/HHS: Team Science Approaches Integrating Experimental and Computational Brain Aging Models (R21/R33 Clinical Trial Not Allowed) Monday, February 13, 2023 - Supports interdisciplinary collaborations involving both experimental and computational researchers to simultaneously address a targeted research question in brain aging and Alzheimer’s disease with the goal of developing a sustainable interdisciplinary collaboration across experimental and computational laboratories to support projects that address key research questions in brain aging and AD/ADRD.  Amount: $3,775,000 Due Date: 9/22/23 More Information
NIH: NIDA Research Center of Excellence Grant Program (P50 Clinical Trial Optional) Friday, January 20, 2023 - Supports research Centers that (1) conduct substance use and addiction research in any area of NIDA’s mission, including the intersection of substance use/addiction and HIV, (2) foster outstanding innovative science, (3) are multidisciplinary, thematically integrated, synergistic, and (4) serve as national resource(s) to provide educational and outreach activities to relevant research communities, educational organizations, the […]
NIH: Development of Novel Nonsteroidal Contraceptive Methods Tuesday, October 18, 2022 - Supports multidisciplinary research approaches for the development of novel nonsteroidal contraceptive products for men and women that act prior to fertilization. Amount: $3,020,000 Due Date: 3/29/23 More information
NIH: NIMH Biobehavioral Research Awards for Innovative New Scientists (NIMH BRAINS) Tuesday, September 13, 2022 - Supports the research and research career advancement of outstanding, exceptionally productive scientists who are in the early, formative stages of their careers.
NIH: BRAIN Initiative: Engineering and optimization of molecular technologies for functional dissection of neural circuits (UM1 Clinical Trial Not Allowed) Wednesday, September 7, 2022 - Funds research to develop molecular tools of high impact that are targetable to brain cell types for the monitoring and manipulation of neural circuits.
NIH: BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs Wednesday, March 16, 2022 - Supports interdisciplinary teams to elucidate the contributions of dynamic circuit activity to a specific behavioral or neural system.
NSF Smart and Connected Communities (S&CC) Wednesday, December 8, 2021 - The S&CC program supports integrative research that addresses fundamental technological and social science dimensions of smart and connected communities and pilots solutions together with communities.
NSF: Biodiversity on a Changing Planet (BoCP) Thursday, October 21, 2021 - The Biodiversity on a Changing Planet program is a cross directorate and international program led by NSF that invites submission of interdisciplinary proposals addressing grand challenges in biodiversity science within the context of unprecedented environmental change.
CDC: Vector-Borne Disease Regional Centers of Excellence Thursday, October 21, 2021 - The purpose of this NOFO is to support research to improve national capacity to address the growing problem of vector-borne diseases via continued support for regional Centers of Excellence for Vector-Borne Diseases.
NSF: Harnessing the Data Revolution (HDR): Transdisciplinary Research in Principles of Data Science Phase II (TRIPODS) Monday, October 18, 2021 - NSF's Harnessing the Data Revolution Big Idea is a national-scale activity to enable new modes of data-driven discovery that will allow fundamental questions to be asked and answered at the frontiers of science and engineering.
NSF: Computer and Information Science and Engineering (CISE) Community Research Infrastructure Program Monday, October 18, 2021 - The Computer and Information Science and Engineering Community Research Infrastructure program drives discovery and learning in the core CISE disciplines by funding the creation and enhancement of world-class research infrastructure.
NIH: Development of Microbiome-Related Approaches for Diagnosis/Mitigation/Treatment of Radiation Injuries (U01 Clinical Trial Not Allowed) Monday, October 11, 2021 - The purpose of this FOA is to support research that will advance the understanding of how the microbiome affects radiation injury.
DOC: US Marine Life Observations: Coordinated Marine Biodiversity Observation Network (MBON) and Animal Telemetry Network (ATN) Activities to Ensure Resilient, Productive Ecosystems and Human Communities in the Face of Change Monday, October 11, 2021 - This program supports proposals that: (1) build upon the foundation established by MBON, ATN and the US IOOS Regional Associations to work across sectors and disciplines towards an integrated, sustained marine life observing capability for the U.S. ocean, coasts and Great Lakes, from estuaries to the deep ocean.
NIH: Systems Biology for Infectious Diseases (U19 Clinical Trial Not Allowed) Monday, October 11, 2021 - The purpose of the FOA is to support research that employs systems biology approaches to human pathogens.
NIH: SPARC Human Open Research Neural Engineering Technologies (HORNET) Initiative (U41) Monday, October 11, 2021 - This U41 opportunity will fund centers to create interoperable open-source modules that can be combined into custom profiles for new exploratory and clinical neuromodulation studies in the peripheral nervous system, and for potential applicability in the central nervous system.
NIH: Pediatric Obesity Discovery Science Research to Improve Understanding of Risk and Causal Mechanisms for Obesity in Early Life (R01) Monday, October 11, 2021 - The purpose of this FOA is to support innovative, discovery research studies to better characterize early-life risk factors and elucidate underlying causal mechanisms through which these risk factors contribute to the development of obesity during infancy and early childhood.
NSF: Integrative Research in Biology (IntBIO) Saturday, September 25, 2021 - This solicitation invites submission of collaborative proposals that tackle bold questions in biology and require an integrated approach to make substantive progress.
NSF: Cyberinfrastructure for Sustained Scientific Innovation (CSSI) Saturday, September 25, 2021 - This solicitation expands the Cyberinfrastructure for Sustained Scientific Innovation program by adding a new project class: Transition to Sustainability.
NSF: Biology Integration Institutes (BII) Tuesday, September 21, 2021 - The NSF Directorate for Biological Sciences program for Biology Integration Institutes (BII) supports diverse and collaborative teams of researchers investigating questions that span multiple disciplines within and beyond biology.
NSF: EHR Core Research – Resource Coordination Hub (ECR Hub) Monday, September 13, 2021 - NSF seeks proposals to create an EHR Core Research (ECR) Resource Coordination Hub (ECR Hub) that will be an intellectual partner to the ECR:Core and the ECR:BCSER grantee communities and the NSF to enhance the overall influence and reach of ECR STEM education research investments.
DOE: Natural Gas Demand Response Pilot Program Monday, September 13, 2021 - FOA soliciting cooperative agreements for the development of multiple regional natural gas demand response pilot programs in collaboration with utilities, local distribution companies and public utility commissions.
NEH: Digital Humanities Advancement Grants Monday, September 13, 2021 - computationally challenging digital projects, leading to work that can scale to enhance scholarly research, teaching and public programming in the humanities.
NSF: Facility and Instrumentation Request Process (FIRP) Monday, September 13, 2021 - The Facility and Instrumentation Request Process (FIRP) solicitation describes the mechanism by which the research community can propose projects that require access to instrumentation and facilities sponsored by the FARE Program.
NIH: National Cancer Institute Youth Enjoy Science Research Education Program (R25) Friday, September 3, 2021 - This funding opportunity seeks to facilitate the education of students from diverse backgrounds underrepresented in biomedical research who will become knowledgeable about cancer, and available to focus on cancer later in their careers.