Research Insights
Large Grant Opportunities
Sign up for the large grant opportunities and limited submissions listserv. The Office of Research hosts a listserv that shares large funding opportunities and internal competition announcements weekly as well as a calendar of current limited submissions opportunities.
Patient-Centered Outcomes Research Institute: Addressing Violence and Trauma Topical PCORI Funding Announcement — Cycle 2 2025 Wednesday, April 9, 2025 - This program funds high-quality, patient-centered comparative clinical effectiveness research projects that address violence and trauma within the following 3 Special Areas of Emphasis: Intentional Trauma; Unintentional Trauma; Substance Use and Trauma. Amount: Up to $12,000,000 Due Date: 05/13/2025 (LOI) More Information
Patient-Centered Outcomes Research Institute: Intellectual and Developmental Disabilities Topical PCORI Funding Announcement — Cycle 2 2025 Friday, April 4, 2025 - This program seeks to fund high-quality patient-centered comparative clinical effectiveness research projects that focus on people with intellectual and developmental disabilities. Amount: Up to $12,000,000 Due Date: 05/13/2025 (LOI) More Information
NOAA: Joint Hydrographic Center 2025 Friday, April 4, 2025 - This purpose of this program is to solicit proposals for a single cooperative agreement between NOAA and an institution of higher learning to operate and maintain a Joint Hydrographic Center. Amount: $47,500,000 Due Date: 05/27/2025 More Information
NFWF: National Coastal Resilience Fund Friday, April 4, 2025 - This program will make investments in planning, design, and implementation of nature-based solutions to enhance protection for coastal communities from the impacts of storms, floods, and other natural hazards while improving habitats for fish and wildlife. Amount: $100,000 – $10,000,000 Due Date: 05/06/2025 (Pre-Proposals); 07/17/2025 (Invited Full Proposals) More Information
William T. Grant Foundation: Research Grants on Improving the Use of Research Evidence Wednesday, March 26, 2025 - This program supports research on strategies focused on improving the use, usefulness, and impact of evidence in ways that benefit young people ages 5-25 in the United States. Amount: $100,000 – $1,000,000 (Major Research Grants) Due Date: 05/07/2025 More Information
DoD: FY2026 Multidisciplinary Research Program of the University Research Initiative (MURI) Wednesday, March 26, 2025 - This program addresses high-risk basic research and attempts to understand or achieve something that has never been done before. Amount: Typically, up to $1,500,000 per year Due Date: 05/02/2026 (White Papers); 09/05/2025 (Full Proposals) More Information
DoD: Bilateral Academic Research Initiative (Bari) Program Ministry Of Trade, Industry And Energy (MOTIE) Wednesday, March 19, 2025 - This program addresses high risk basic research as an international collaboration. The goal of this program is to produce significant scientific breakthroughs and knowledge that will be critical steps in enabling revolutions in robotics technology and stimulate the emergence of new industries. Amount: $6,000,000 Due Date: 05/30/2025 (White Papers) More Information
Helmsley Charitable Trust: Understanding and Targeting Innate Immunity in Type 1 Diabetes Pathogenesis Wednesday, March 19, 2025 - This program seeks to support studies that aim to evaluate or modulate the function of innate immune cells and pathways in Type 1 Diabetes, with an emphasis on human disease during relatively early stages of disease (i.e., autoantibody positivity through early onset of clinical disease). Amount: $900,000 (Lab-based studies); $1,500,000 (Clinic-based studies) Due Date: 4/30/2025 (Concept Notes) […]
Michael J. Fox Foundation: Aligning Science Across Parkinson’s: Collaborative Research Network – Scientific Track Friday, March 14, 2025 - This Initiative invites applications from collaborative teams to join the ASAP Collaborative Research Network (CRN). For this cycle, applications within the Scientific Track that focus on dissecting the mechanisms that contribute to Parkinson’s disease heterogeneity will be considered. Amount: $9,000,000 Due Date: 03/20/2025 (LOI); 08/07/2025 (Invited Proposals) More Information
Michael J. Fox Foundation: Aligning Science Across Parkinson’s: Collaborative Research Network – Technical Track Friday, March 14, 2025 - This Initiative invites applications from collaborative teams to join the ASAP Collaborative Research Network (CRN), which works to address high-priority research questions in an effort to advance our understanding of Parkinson’s disease (PD) and drive new ideas into the R&D pipeline. For this cycle, applications within the Technical Track that focus on the development of […]
NEH: Humanities Initiatives at Colleges and Universities Friday, March 14, 2025 - This program strengthens the teaching and study of the humanities at institutions of higher education by developing new or improving existing humanities programs, educational resources, or coursework. Amount: $150,000 Due Date: 03/25/2025 (Optional Draft); 05/06/2025 (Full Proposal) More Information
Wellcome Leap: Cutting Alzheimer’s Risk through Endocrinology (CARE) program Wednesday, February 26, 2025 - CARE is focused on the intersection of neuroendocrine risks and neurodegeneration so as to identify personalized preventative strategies and treatments, with the ultimate goal of cutting women’s lifetime risk of Alzheimer’s in half. Amount: Unspecified Due Date: 03/14/2025 (Abstracts); 04/28/2025 (Full Proposals) More Information
NSF: Growing Convergence Research (GCR) Friday, February 21, 2025 - This program aims to cultivate and grow the earliest foundations of convergent approaches for addressing a specific and compelling problem. Proposals should explore novel avenues not previously investigated that are at the forefront of advancing science through deep integration. Amount: $1,200,000 (Phase I); $2,400,000 (Phase II) Due Date: 02/09/2026 More Information
NIH: Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) (U54 Clinical Trial Optional) Friday, February 21, 2025 - This program aims to achieve a stronger national cancer program and address challenges in cancer and cancer disparities research, education, and outreach, as well as cancer’s impact on underserved populations. Amount: $12,835,000 – $16,610,000 Due Date: 10/09/2025More Information
DOD: Fiscal Year (FY) 2025 INnovations in Qubit Science for Fault Tolerant Quantum Computing (INQS) Program Friday, February 21, 2025 - This program invites proposals for basic research into solid-state qubits for quantum computing at various stages of maturity. Amount: $300,000 – $3,750,000 Due Date: 03/27/2025 (White Papers); 05/12/2025 (Full Proposals) More Information
The Mark Foundation for Cancer Research: Early Detection Award Wednesday, February 12, 2025 - This program supports projects focused on accelerating the development of effective new approaches to the early detection of cancer. These projects will advance our understanding of the origins and risk stratifications of recalcitrant cancers and accelerate the development of technological and methodological innovation in early cancer detection and interception. Amount: $2,000,000 Due Date: 03/10/2025 (LOI); 06/17/2025 (Full […]
NEH: Humanities Initiatives at Colleges and Universities Wednesday, January 29, 2025 - This program strengthens the teaching and study of the humanities at institutions of higher education by developing new or improving existing humanities programs, educational resources, or coursework. Amount: Up to $150,000 Due Date: 03/25/2025 (Optional Draft); 05/06/2025 (Full Proposal) More Information
NIH: Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Individuals, and Persons with Disabilities (UG3/UH3 – Clinical Trial Optional) Friday, January 17, 2025 - This program’s purpose is to leverage NICHD clinical research network infrastructure relevant to infants, children, women, pregnant and lactating individuals, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. Amount: $6,250,000 DueDate: 07/15/2025 More Information
NIH: Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimer’s Disease and Related Dementias (R01 Clinical Trial Not Allowed) Wednesday, January 8, 2025 - The central goal of this NOFO is to establish robust proof of concept in mouse models or cell-based models of AD/ADRD that will enable rational drug repositioning and the development of precision combination therapies for the treatment and prevention of AD/ADRD. Amount: $7,550,000 Due Date: 06/09/2025; 10/06/2025 More Information
NIH: Alzheimer’s Drug-Development Program (U01 Clinical Trial Optional) Friday, December 13, 2024 - This program invites applications proposing pre-clinical and early stage clinical (Phase I) development of novel small-molecule and biologic drug candidates that aim to prevent Alzheimer’s disease, slow its progression, or treat its cognitive and behavioral symptoms. Amount: $11,325,000 Due Date: 05/05/2025 (LOI); 06/05/2025 (Full Proposal) More information
NSF-NEH: Dynamic Language Infrastructure – Documenting Endangered Languages Senior Research Grants Friday, December 13, 2024 - This partnership between the NSF and NEH supports projects to develop and advance knowledge concerning dynamic language infrastructure in the context of endangered human languages — languages that are both understudied and at risk of falling out of use. Amount: $450,000 Due Date: 09/15/2025 More information
NIH: NIDA Avant-Garde Program for HIV and Substance Use Disorder Research (DP1) Wednesday, December 4, 2024 - This program supports exceptionally creative scientists, who propose high-impact studies that open new areas of HIV research in the context of substance use and Substance Use Disorders (SUD) and/or lead to new avenues for prevention and treatment of HIV in people with SUD. Amount: $5,285,000 Due Date: 07/15/2025 (LOI); 08/15/2025 (Full Proposal) More Information
National Archives: Archival Projects Wednesday, December 4, 2024 - This program supports archival projects that significantly improve online public discovery and use of historical records collections. Amount: $150,000 Due Date: 02/18/2025 (Optional Draft); 05/07/2025 (Full Proposal) More Information
Georgia Network for Electric Mobility Seed Grants Tuesday, November 26, 2024 - This program supports interdisciplinary research in e-mobility related topics along the electric vehicle/mobility value chain such as battery manufacturing and rare earth materials mining, supply chain and logistics, vehicle manufacturing, charging infrastructure and utilities, sales and consumer knowledge, and battery and EV components/materials recycling. Amount: $40,000 up to $60,000 per award Proposal due date: December 18, […]
NEH: Landmarks of American History and Culture Wednesday, November 13, 2024 - This program supports a series of one-week residential, virtual, and combined format workshops across the nation to enhance how K-12 educators and higher education faculty and humanities professionals incorporate place-based approaches to humanities teaching and scholarship. Amount: $190,000 Due Date: 01/06/2025 (Optional Draft); 12/12/2025 (Full Proposal) More Information
NSF: Computer and Information Science and Engineering (CISE): Core Programs, Large Projects Wednesday, September 18, 2024 - This solicitation invites proposals on bold new scientific ideas tackling ambitious fundamental research problems that cross the boundaries of two or more CISE core programs, which range from Computing and Communications to Computer and Network Systems, to Information and Intelligence Systems. Amount: $3,000,000 – $5,000,000 Due Date: 09/29/2025 More Information
NIH: Building Interdisciplinary Research Careers in Women’s Health (BIRCWH) (K12 Clinical Trial Optional) Monday, March 18, 2024 - This program supports mentored research career development of junior faculty members who have recently completed clinical training or postdoctoral fellowships, and who will be engaged in interdisciplinary basic, translational, data science, behavioral, clinical, and/or health services research relevant to the health of women and, where appropriate, the use of both sexes to better understand the […]
NIH: Individually Measured Phenotypes to Advance Computational Translation in Mental Health Wednesday, May 10, 2023 - Supports the work of the research projects funded under the Individually Measured Phenotypes to Advance Computational Translation in Mental Health (IMPACT-MH) initiative described in the companion announcement RFA-MH-23-105. Amount: $18,875,000 Due Date: 6/14/23 More Information
NEH: Digital Projects for the Public Wednesday, March 22, 2023 - This program supports projects that interpret and analyze humanities content in primarily digital platforms and formats, such as websites, mobile applications and tours, interactive touch screens and kiosks, games, and virtual environments. Amount: $400,000 Due Date: 6/14/23 More Information
NIH: Development of Novel Nonsteroidal Contraceptive Methods Tuesday, October 18, 2022 - Supports multidisciplinary research approaches for the development of novel nonsteroidal contraceptive products for men and women that act prior to fertilization. Amount: $3,020,000 Due Date: 3/29/23 More information
NIH: BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs Wednesday, March 16, 2022 - Supports interdisciplinary teams to elucidate the contributions of dynamic circuit activity to a specific behavioral or neural system.
NSF: Biodiversity on a Changing Planet (BoCP) Thursday, October 21, 2021 - The Biodiversity on a Changing Planet program is a cross directorate and international program led by NSF that invites submission of interdisciplinary proposals addressing grand challenges in biodiversity science within the context of unprecedented environmental change.
CDC: Vector-Borne Disease Regional Centers of Excellence Thursday, October 21, 2021 - The purpose of this NOFO is to support research to improve national capacity to address the growing problem of vector-borne diseases via continued support for regional Centers of Excellence for Vector-Borne Diseases.
NSF: Harnessing the Data Revolution (HDR): Transdisciplinary Research in Principles of Data Science Phase II (TRIPODS) Monday, October 18, 2021 - NSF's Harnessing the Data Revolution Big Idea is a national-scale activity to enable new modes of data-driven discovery that will allow fundamental questions to be asked and answered at the frontiers of science and engineering.
NSF: Computer and Information Science and Engineering (CISE) Community Research Infrastructure Program Monday, October 18, 2021 - The Computer and Information Science and Engineering Community Research Infrastructure program drives discovery and learning in the core CISE disciplines by funding the creation and enhancement of world-class research infrastructure.
NIH: Development of Microbiome-Related Approaches for Diagnosis/Mitigation/Treatment of Radiation Injuries (U01 Clinical Trial Not Allowed) Monday, October 11, 2021 - The purpose of this FOA is to support research that will advance the understanding of how the microbiome affects radiation injury.
DOC: US Marine Life Observations: Coordinated Marine Biodiversity Observation Network (MBON) and Animal Telemetry Network (ATN) Activities to Ensure Resilient, Productive Ecosystems and Human Communities in the Face of Change Monday, October 11, 2021 - This program supports proposals that: (1) build upon the foundation established by MBON, ATN and the US IOOS Regional Associations to work across sectors and disciplines towards an integrated, sustained marine life observing capability for the U.S. ocean, coasts and Great Lakes, from estuaries to the deep ocean.
NIH: Systems Biology for Infectious Diseases (U19 Clinical Trial Not Allowed) Monday, October 11, 2021 - The purpose of the FOA is to support research that employs systems biology approaches to human pathogens.
NIH: SPARC Human Open Research Neural Engineering Technologies (HORNET) Initiative (U41) Monday, October 11, 2021 - This U41 opportunity will fund centers to create interoperable open-source modules that can be combined into custom profiles for new exploratory and clinical neuromodulation studies in the peripheral nervous system, and for potential applicability in the central nervous system.
NIH: Pediatric Obesity Discovery Science Research to Improve Understanding of Risk and Causal Mechanisms for Obesity in Early Life (R01) Monday, October 11, 2021 - The purpose of this FOA is to support innovative, discovery research studies to better characterize early-life risk factors and elucidate underlying causal mechanisms through which these risk factors contribute to the development of obesity during infancy and early childhood.
NSF: Integrative Research in Biology (IntBIO) Saturday, September 25, 2021 - This solicitation invites submission of collaborative proposals that tackle bold questions in biology and require an integrated approach to make substantive progress.
NSF: Cyberinfrastructure for Sustained Scientific Innovation (CSSI) Saturday, September 25, 2021 - This solicitation expands the Cyberinfrastructure for Sustained Scientific Innovation program by adding a new project class: Transition to Sustainability.
NSF: Biology Integration Institutes (BII) Tuesday, September 21, 2021 - The NSF Directorate for Biological Sciences program for Biology Integration Institutes (BII) supports diverse and collaborative teams of researchers investigating questions that span multiple disciplines within and beyond biology.
NSF: EHR Core Research – Resource Coordination Hub (ECR Hub) Monday, September 13, 2021 - NSF seeks proposals to create an EHR Core Research (ECR) Resource Coordination Hub (ECR Hub) that will be an intellectual partner to the ECR:Core and the ECR:BCSER grantee communities and the NSF to enhance the overall influence and reach of ECR STEM education research investments.
DOE: Natural Gas Demand Response Pilot Program Monday, September 13, 2021 - FOA soliciting cooperative agreements for the development of multiple regional natural gas demand response pilot programs in collaboration with utilities, local distribution companies and public utility commissions.
NEH: Digital Humanities Advancement Grants Monday, September 13, 2021 - computationally challenging digital projects, leading to work that can scale to enhance scholarly research, teaching and public programming in the humanities.
NSF: Facility and Instrumentation Request Process (FIRP) Monday, September 13, 2021 - The Facility and Instrumentation Request Process (FIRP) solicitation describes the mechanism by which the research community can propose projects that require access to instrumentation and facilities sponsored by the FARE Program.
NIH: National Cancer Institute Youth Enjoy Science Research Education Program (R25) Friday, September 3, 2021 - This funding opportunity seeks to facilitate the education of students from diverse backgrounds underrepresented in biomedical research who will become knowledgeable about cancer, and available to focus on cancer later in their careers.
NSF: Mathematical Sciences Research Institutes Tuesday, July 6, 2021 - The goals of the Mathematical Sciences Research Institutes program include advancing research in the mathematical sciences, increasing the impact of the mathematical sciences in other disciplines, and expanding the talent base engaged in mathematical research in the United States.
FY2021 Vannevar Bush Faculty Fellowship Friday, July 10, 2020 - This FOA seeks distinguished researchers for the purpose of conducting innovative basic research in areas of interest to the DoD and fostering long-term relationships between the VBFF Fellows and the DoD.
Tobacco Use and HIV in Low and Middle-Income Countries (U01 Clinical Trial Optional) Friday, July 10, 2020 - This FOA supports the development and evaluation of tobacco cessation interventions tailored to HIV-positive populations, including those with comorbidities such as tuberculosis (TB), in low-resource settings in low- and middle-income countries.
Limited Submission: Continuation of the Human Pancreas Analysis Program (HPAP) for Type 1 Diabetes (HPAP-T1D) (U01 Clinical Trial Not Allowed) Friday, July 10, 2020 - This FOA will support one team of investigators with combined expertise in human pancreas physiology and pathophysiology; collection, processing and multimodal analysis of human pancreatic tissues; and biological database building, curation and management.
Network of the National Library of Medicine Evaluation Center (U24) (Clinical Trial Not Allowed) Monday, July 6, 2020 - The NNLM Evaluation Center (NEC) will coordinate the assessment of the impact, efficacy and value of NNLM activities, services, and resources. A special focus will be placed on assessing community engagement and measuring its impact on persons who experience health disparities, and populations underrepresented in biomedical research.
Technical Assistance and Dissemination to Improve Services and Results for Children with Disabilities and Demonstration and Training Programs Monday, July 6, 2020 - The purpose of the program is to promote academic achievement and to improve results for children with disabilities by providing TA, supporting model demonstration projects, disseminating useful information, and implementing activities that are supported by scientifically based research.
Pediatric Biospecimen Procurement Center (BPC) Supporting the Developmental Gene Expression (dGTEx) Project (U24 Clinical Trial Not Allowed) Monday, July 6, 2020 - The purpose of this funding opportunity is for support of a Biospecimen Procurement Center (BPC) to enroll suitable pediatric donors and provide high quality tissue samples for analyses to the Laboratory, Data Analysis, and Coordinating Center.