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Announcements Find Funding Large Grant Opportunities

This program supports research on STEM education in one or more of three research areas: STEM learning and learning environments, broadening participation in STEM, and STEM workforce development.

Amount: $500,000 (Level I); $1,500,000 (Level II); $2,500,000 (Level III)

Due Date: 10/01/2026

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Announcements Find Funding Large Grant Opportunities

This NOFO invites applications from eligible organizations to establish a Data Coordination and Integration Center (DCIC) which will support the coordination and integration of data from both the HEAL INTERACT program and progressively facilitate broader integration of related musculoskeletal datasets and programs. The Center will lead efforts for managing and integrating complex pain-associated data types and information from the INTERACT Consortium and progressively related datasets. It will also establish a web-accessible information system and disseminate datasets that can facilitate hypothesis generation and be widely used throughout the research community. 

Amount: $4,000,000

Due Date: 10/06/2026

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Announcements Find Funding Large Grant Opportunities

This product-driven award mechanism intends to support the translation of promising preclinical findings into products for clinical applications, including prevention, detection, diagnosis, treatment, or quality of life, for a disease or condition related to one of the congressionally directed FY26 PRMRP topic areas and one of the FY26 PRMRP strategic goals. The program expects the research proposed will take an already established proof-of-concept or prototype through the final stages of preclinical development.

Amount: $5,600,000

Due Date: 07/23/2026 (LOIs); 08/06/2026 (Full Proposals)

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Announcements Find Funding Large Grant Opportunities

This award supports clinical research and/or clinical trials using a combination of scientific disciplines including occupational science, psychology, psychometrics, biostatistics and epidemiology, surveillance, implementation science, and population health. Applications must address and provide a solution to one of the congressionally directed FY26 PRMRP topic areas and one of the FY26 PRMRP strategic goals.

Amount: $4,200,000

Due Date: 07/23/2026 (LOIs); 08/06/2026 (Full Proposals)

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Announcements Find Funding Large Grant Opportunities

This award supports the rapid implementation of clinical trials with the potential to have significant impact on the treatment and management of a disease or condition addressed in one of the congressionally directed FY26 PRMRP topic areas and FY26 PRMRP strategic goals.

Amount: $800,000 (Planning); $6M (Level 1); $10M (Level 2); $20M (Level 3)

Due Date: 07/23/2026 (Pre-Proposals); 09/22/2026 (Invited Full Proposals)

This award supports the rapid implementation of clinical trials with the potential to have significant impact on the treatment and management of a disease or condition addressed in one of the congressionally directed FY26 PRMRP topic areas and FY26 PRMRP strategic goals.

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Announcements Find Funding Large Grant Opportunities

This NOFO invites applications which include at least two related, synergistic Research Projects that share a common central theme, focus, and/or overall objective; an Administrative Core; and optional Scientific Core(s). Applications must address scientific areas relevant to the NIAID mission.

Amount: Unspecified

Due Date: 09/26/2026

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Announcements Find Funding Large Grant Opportunities

The BCRP seeks to accelerate high-impact research with clinical relevance, encourage innovation and stimulate creativity, and facilitate productive collaborations. The intent of the Breakthrough Award is to support promising research with high potential to lead to or make breakthroughs in breast cancer. The FY26 Breakthrough Award mechanism contains four different funding levels designed to support major (but not all) stages of research that will lead to clinical application.

Amount: $21,000,000

Due Date: 06/12/2026 (Pre-Proposals); 09/30/2026 (Invited Full Proposals)

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Announcements Find Funding Large Grant Opportunities

This program supports individuals who are early in their careers with significant potential to effect meaningful change in breast cancer.

Amount: $4,900,000

Due Date: 06/24/2026 (LOI); 07/08/2026 (Full Applications)

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Announcements Find Funding Large Grant Opportunities

This award supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of cancer within at least one of the FY26 PRCRP Topic Areas. Clinical trials proposed may evaluate promising new products, pharmacologic agents, devices, clinical guidance, and/or emerging approaches and technologies.

Amount: $4,500,000

Due Date: 06/26/2026 (Pre-Proposals); 08/10/2026 (Full Proposals)

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Announcements Find Funding Large Grant Opportunities

This program supports the formation of one Resource Center (RC) that will support promising strategies and products for tissue engineering and regenerative medicine (TE/RM). The RC will capitalize on their available clinical, scientific, industrial, regulatory, and commercialization expertise to select, support, and guide Interdisciplinary Translational Projects (ITPs) in the areas of therapeutics (including adult stem cell-based treatments), sensors, and diagnostics.

Amount: $13,680,000

Due Date: 07/10/2026

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