Category: Large Grant Opportunities

NSF’s Harnessing the Data Revolution (HDR) Big Idea is a national-scale activity to enable new modes of data-driven discovery that will allow fundamental questions to be asked and answered at the frontiers of science and engineering. Through this NSF-wide activity, HDR will generate new knowledge and understanding, and accelerate discovery and innovation. The HDR vision is realized through an interrelated set of efforts in foundations of data science; algorithms and systems for data science; data-intensive science and engineering; data cyberinfrastructure; and education and workforce development. Each of these efforts is designed to amplify the intrinsically multidisciplinary nature of the emerging field of data science. The HDR Big Idea will establish theoretical, technical and ethical frameworks that will be applied to tackle data-intensive problems in science and engineering, contributing to data-driven decision making that impacts society.

Amount: $10,000,000

Deadline: Nov. 16, 2021 (LOI); Jan. 18, 2022 (full application)

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The Computer and Information Science and Engineering (CISE) Community Research Infrastructure (CCRI) program drives discovery and learning in the core CISE disciplines of the three participating divisions—Computing and Communication Foundations (CCF), Computer and Network Systems (CNS), and Information and Intelligent Systems (IIS)—by funding the creation and enhancement of world-class research infrastructure. This research infrastructure will specifically support diverse communities of CISE researchers pursuing focused research agendas in computer and information science and engineering.

Amount: Up to $5,000,000

Deadline: Jan. 11, 2022 and June 23, 2022

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The purpose of this Funding Opportunity Announcement is to support research that will advance the understanding of how the microbiome affects radiation injury and to develop medical countermeasures (MCMs) that target the microbiome to prevent or mitigate radiation injury.

Amount: $2,642,500

Deadline: Feb. 9, 2022

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This program supports proposals that: (1) build upon the foundation established by MBON, ATN and the US IOOS Regional Associations to work across sectors and disciplines towards an integrated, sustained marine life observing capability for the U.S. ocean, coasts and Great Lakes, from estuaries to the deep ocean; (2) advance technologies for efficient and/or automated collection of species and associated habitat observations; (3) enable open access to biodiversity data and information; and (4) utilize these observations, technologies, and data to address place-based management, conservation and restoration needs.

Amount: $2,500,000

Deadline: Dec. 17, 2021

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The purpose of the Funding Opportunity Announcement is to support research that employs systems biology approaches to human pathogens. The approach will generate and integrate large datasets into models that guide in vitro, in vivo and clinical studies, with the goals of predicting disease severity, predicting responses to vaccines and therapeutics, and identifying candidate targets for interventions.

Amount: $11,325,000

Deadline: Dec. 14, 2021 (LOI); Jan. 14, 2022 (full application)

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This U41 opportunity will fund centers to create interoperable open-source modules that can be combined into custom profiles for new exploratory and clinical neuromodulation studies in the peripheral nervous system, and for potential applicability in the central nervous system. The centers will disseminate the open-source neuromodulation resources broadly.

Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project.

Deadline: Dec. 12, 2021 (LOI); Jan. 12, 2022 (full application)

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The purpose of this Funding Opportunity Announcement (FOA) is to support innovative, discovery research studies to better characterize early-life risk factors and elucidate underlying causal mechanisms through which these risk factors contribute to the development of obesity during infancy and early childhood. Studies should aim to understand biological mechanisms that mediate behavioral and/or metabolic risk for obesity development in young children and how risk may be modified by other contributors such as psychosocial, contextual and/or environmental factors. This FOA encourages multidisciplinary teams of scientists including, but not limited to, those with expertise in basic, translational, clinical and behavioral research.

Amount: $3,775,000

Deadline: Feb. 8, 2022 (LOI); March 8, 2022 (full application)

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This solicitation invites submission of collaborative proposals that tackle bold questions in biology and require an integrated approach to make substantive progress. Integrative biological research spans subdisciplines and incorporates cutting-edge methods, tools and concepts from each to produce groundbreaking biological discovery. The research should be synergistic and produce novel, holistic understanding of how biological systems function and interact across different scales of organization, e.g., from molecules to cells, tissues to organisms, species to ecosystems and the entire Earth.

Amount: $2,000,000

Deadline: Jan. 25, 2022

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The Cyberinfrastructure for Sustained Scientific Innovation (CSSI) umbrella program seeks to enable funding opportunities that are flexible and responsive to the evolving and emerging needs in cyberinfrastructure (CI). This solicitation expands the CSSI program by adding a new project class: Transition to Sustainability. The program continues to emphasize integrated CI services, quantitative metrics with targets for delivery and usage of these services, and community creation.

Amount: $600,000 – $5,000,000

Deadline: Dec. 8, 2021

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The NSF Directorate for Biological Sciences program for Biology Integration Institutes (BII) supports diverse and collaborative teams of researchers investigating questions that span multiple disciplines within and beyond biology. The goal is to stimulate creative integration of disparate fields using innovative experimental, theoretical and modeling approaches to discover underlying principles operating across multiple levels of life, from molecules to cells, organisms, species, ecosystems, biomes and the entire Earth. Submission to this opportunity requires early notification and coordination with the Office of Research. Interested faculty are advised to apply to the Major Integrative Proposal Planning (MIPP) Program from the Office of Research.

Amount: $12,500,000

Deadline: Jan. 12, 2022

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