The central goal of this NOFO is to establish robust proof of concept in mouse models or cell-based models of AD/ADRD that will enable rational drug repositioning and the development of precision combination therapies for the treatment and prevention of AD/ADRD.
Amount: $7,550,000
Due Date: 06/09/2025; 10/06/2025
This program supports research to advance the development of safe and effective medications for the treatment of Substance Use Disorders (SUD). The goal is to fund studies that will have high impact and quickly yield the necessary results to advance medications closer to FDA approval.
Amount: $22,650,000
Due Date: 03/10/2025 (LOI); 04/10/2025 (Full Proposal)
This program supports work that enables scientists and scientific discovery by improving the security, robustness, and trustworthiness of cyberinfrastructure.
Amount: Varies by award type
Due Date: 04/02/2025
This program encourages multi-PI, multi-institutional research to submit proposals on transformative approaches and solutions in materials, devices, theory, and systems to realize the innovative REsearch in FLoquet Engineered QuanTum Systems (REFLEQTS).
Amount: $3,000,000
Due Date: 01/24/2025 (Expression of Interest); 03/14/2025 (Full Proposal)
This program invites applications proposing pre-clinical and early stage clinical (Phase I) development of novel small-molecule and biologic drug candidates that aim to prevent Alzheimer’s disease, slow its progression, or treat its cognitive and behavioral symptoms.
Amount: $11,325,000
Due Date: 05/05/2025 (LOI); 06/05/2025 (Full Proposal)
This partnership between the NSF and NEH supports projects to develop and advance knowledge concerning dynamic language infrastructure in the context of endangered human languages — languages that are both understudied and at risk of falling out of use.
Amount: $450,000
Due Date: 09/15/2025
This program supports exceptionally creative scientists, who propose high-impact studies that open new areas of HIV research in the context of substance use and Substance Use Disorders (SUD) and/or lead to new avenues for prevention and treatment of HIV in people with SUD.
Amount: $5,285,000
Due Date: 07/15/2025 (LOI); 08/15/2025 (Full Proposal)
This program supports archival projects that significantly improve online public discovery and use of historical records collections.
Amount: $150,000
Due Date: 02/18/2025 (Optional Draft); 05/07/2025 (Full Proposal)
This program supports interdisciplinary research in e-mobility related topics along the electric vehicle/mobility value chain such as battery manufacturing and rare earth materials mining, supply chain and logistics, vehicle manufacturing, charging infrastructure and utilities, sales and consumer knowledge, and battery and EV components/materials recycling.
Amount: $40,000 up to $60,000 per award
Proposal due date: December 18, 2024 through InfoReady. Funds must be used by December 30, 2025.
This program supports multidisciplinary research programs focused on discovery to early development research to inform new approaches to prevent, diagnose, and treat antibiotic-resistant bacterial infections.
Amount: $11,325,000
Due Date: 02/24/2025 (LOI); 03/26/2025 (Full Proposal)
