This program aims to cultivate and grow the earliest foundations of convergent approaches for addressing a specific and compelling problem. Proposals should explore novel avenues not previously investigated that are at the forefront of advancing science through deep integration.
Amount: $1,200,000 (Phase I); $2,400,000 (Phase II)
Due Date: 02/10/2025
This program supports multidisciplinary research programs focused on discovery to early development research to inform new approaches to prevent, diagnose, and treat antibiotic-resistant bacterial infections.
Amount: $11,325,000
Due Date: 02/24/2025 (LOI); 03/26/2025 (Full Proposal)
This program supports a series of one-week residential, virtual, and combined format workshops across the nation to enhance how K-12 educators and higher education faculty and humanities professionals incorporate place-based approaches to humanities teaching and scholarship.
Amount: $190,000
Due Date: 01/06/2025 (Optional Draft); 12/12/2025 (Full Proposal)
This program aims to establish Centers for Accelerating Phage Therapy to combat ESKAPE pathogens. These Centers will develop preclinical assays, tools, and models and conduct essential studies that facilitate robust phage therapeutics against ESKAPE pathogens, contributing significantly to the fight against antibiotic resistance.
Amount: $9,060,000
Due Date: 12/27/2024 (LOI); 01/28/2025 (Full Proposal)
This program is soliciting applications to pilot the establishment of an integrated resource for users to explore, analyze, and download processed deidentified human brain single-cell transcriptomics and epigenomics data that is harmonized across reference and disease datasets.
Amount: $4,530,000
Due Date: 01/14/2025 (LOI); 02/14/2025 (Full Proposal)
This program offers the opportunity to address research issues and answer engineering challenges associated with complex systems and networks that are not achievable by a single principal investigator or by short-term projects and can only be achieved by interdisciplinary research teams.
Amount: $1,000,000 – $1,500,000
Due Date: 01/22/2025
The overarching goal of this program is to address the challenges and opportunities in associating gene(s) to function, as well as to understand the biological processes relevant for plant transformation in plant systems of relevance to the Biological and Environmental Research mission.
Amount: $750,000 – $3,000,000
Due Date: 12/02/2024 (Pre-Applications); 02/10/2025 (Full Proposals)
This program supports innovative basic research projects that contribute to the advancement of social science and provides new methods and understandings on social and behavioral questions of security and defense-related interest.
Amount: up to $5,000,000
Due Date: 11/29/2024 (White Papers); 02/28/2025 (Full Proposals)
The goal of the Centers is to support collaborative research projects that bridge current personalized medicine efforts in human subjects with advances in animal genomics and genetic manipulation technologies, including the creation of interspecies somatic hybrids.
Amount: $9,437,500
Due Date: 12/15/2024
This program helps cultural institutions meet the complex challenge of preserving large and diverse holdings of humanities materials for future generations by supporting environmentally sustainable preventive care measures.
Amount: $50,000 – $350,000
Due Date: 12/05/2024 (Optional Draft); 01/10/2025 (Full Proposal)
