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Announcements Find Funding Large Grant Opportunities

This program supports projects focused on accelerating the development of effective new approaches to the early detection of cancer. These projects will advance our understanding of the origins and risk stratifications of recalcitrant cancers and accelerate the development of technological and methodological innovation in early cancer detection and interception.

Amount: $2,000,000

Due Date: 03/10/2025 (LOI); 06/17/2025 (Full Proposal)

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Announcements Find Funding Large Grant Opportunities

This program strengthens the teaching and study of the humanities at institutions of higher education by developing new or improving existing humanities programs, educational resources, or coursework.

Amount: Up to $150,000

Due Date: 03/25/2025 (Optional Draft); 05/06/2025 (Full Proposal)

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Announcements Find Funding Large Grant Opportunities

This program’s purpose is to leverage NICHD clinical research network infrastructure relevant to infants, children, women, pregnant and lactating individuals, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies.

Amount$6,250,000

DueDate07/15/2025

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Announcements Find Funding Large Grant Opportunities

The central goal of this NOFO is to establish robust proof of concept in mouse models or cell-based models of AD/ADRD that will enable rational drug repositioning and the development of precision combination therapies for the treatment and prevention of AD/ADRD.

Amount: $7,550,000

Due Date: 06/09/2025; 10/06/2025

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Announcements Find Funding Internal Grants & Awards Funding

The Office of Research announces the FY 2026 cycle for the Faculty Seed Grants in the Sciences and Engineering.

The goal of the Faculty Seed Grants in the Sciences and Engineering is to enable faculty to launch new, promising lines of research for which resources are currently not available. These seed grants are intended to fund pilot research generating preliminary data that will be leveraged to compete for externally funded grant/contract opportunities and contribute to a sustainable program of research and scholarship. Basic and applied research in the social, life, physical sciences, and engineering are eligible for funding through this program. (Note: The Office of Research funds research grants in Humanities and Arts through a separate program managed by the Willson Center).

All faculty (tenure-track and non-tenure track) with research EFT (equivalent full-time) are eligible with the following exceptions: 1) Applicants may not have access to more than $25,000 in institutional or discretionary research funding (e.g., start-up, salary returns, or IDC returns) during the award year (i.e., FY26); 2) Tenured applicants may not have received more than $50,000 in institutional research support in the past three years (FY23 or later). Examples of institutional research support include bridge funding, a Presidential Seed Grant or other internal seed grant; and 3) An applicant may not have received a Faculty Seed Grant from this program within the last three years (an FY23 grant or later).

See the guidelines on the Office of Research Internal Grants webpage. Answers to frequently asked questions, award conditions, and other information are on the Faculty Seed Grants FAQs page.

The deadline for proposal submission is 11:59 pm on Saturday, March 1, 2025.

Grants for successful applications will be awarded with a start date of July 1, 2025 (FY26).

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Announcements Find Funding Large Grant Opportunities

This program invites applications proposing pre-clinical and early stage clinical (Phase I) development of novel small-molecule and biologic drug candidates that aim to prevent Alzheimer’s disease, slow its progression, or treat its cognitive and behavioral symptoms.

Amount: $11,325,000

Due Date: 05/05/2025 (LOI); 06/05/2025 (Full Proposal)

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Announcements Find Funding Large Grant Opportunities

This partnership between the NSF and NEH supports projects to develop and advance knowledge concerning dynamic language infrastructure in the context of endangered human languages — languages that are both understudied and at risk of falling out of use.

Amount: $450,000

Due Date: 09/15/2025

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Announcements Find Funding Large Grant Opportunities

This program supports exceptionally creative scientists, who propose high-impact studies that open new areas of HIV research in the context of substance use and Substance Use Disorders (SUD) and/or lead to new avenues for prevention and treatment of HIV in people with SUD.

Amount: $5,285,000

Due Date: 07/15/2025 (LOI); 08/15/2025 (Full Proposal)

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Announcements Find Funding Large Grant Opportunities

This program supports archival projects that significantly improve online public discovery and use of historical records collections.

Amount: $150,000

Due Date: 02/18/2025 (Optional Draft); 05/07/2025 (Full Proposal)

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Announcements Find Funding Large Grant Opportunities

This program supports interdisciplinary research in e-mobility related topics along the electric vehicle/mobility value chain such as battery manufacturing and rare earth materials mining, supply chain and logistics, vehicle manufacturing, charging infrastructure and utilities, sales and consumer knowledge, and battery and EV components/materials recycling.

Amount: $40,000 up to $60,000 per award

Proposal due date: December 18, 2024 through InfoReady. Funds must be used by December 30, 2025.

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