Announcements Find Funding Large Grant Opportunities

Research Matters

PCORI funding announcement opening moved to cycle 3

PCORI funding announcement opening moves to June 9.

The opening of this PCORI Funding Announcement has been moved back to June 9, 2020.

This PCORI funding announcement invites applications for high-quality comparative effectiveness research (CER) projects that will examine a critical patient-centered research question that is also relevant to decision makers and other stakeholders. For this PFA, investigators should propose an individual-level or cluster randomized controlled trial of significant scale and scope, requiring funding in excess of $10 million in direct costs. The proposed trials should address important decisional dilemmas that require important new evidence about the comparative effectiveness of available interventions. Proposed studies should compare interventions that already have established evidence of efficacy or are in widespread use. Clinical interventions (such as medications, diagnostic tests, or procedures) and delivery system interventions are appropriate for study.


  • LOI: September 29, 2020
  • Full Application: January 12, 2021

More information.