NIH: Drug Discovery For Nervous System Disorders

Significant advances in neuroscience, genetics, and basic behavioral science, together with technological developments, have provided a rich knowledge base for identifying new molecular targets for drug discovery and developing rational pharmacotherapies for the treatment of a wide variety of nervous system disorders. With the wealth of potential new drug targets, the opportunity exists to accelerate the process of drug discovery and development to make quantum leaps toward novel and effective treatments for mental disorders and nervous system disorders associated with aging.

Through this Funding Opportunity Announcement (FOA) the  National Institute of Mental Health (NIMH) National Institute of Drug Abuse and the National Institute of Aging (NIA) encourage the submission of research grant applications that aim to translate this wealth of basic science findings into the conceptualization, discovery, and preclinical evaluation of innovative therapeutics for mental illnesses and nervous system disorders associated with aging, with the goal of accelerating the development of new treatments for these diseases.

The objective of this FOA is to stimulate research in the discovery, design, and preclinical testing of innovative and effective therapeutics aimed at prevention or treatment of nervous system disorders of primary interest to the NIMH, NIDA and NIA. Projects focused on novel approaches and targets are highly encouraged. Projects designed for target identification or elucidation of disease mechanisms are not covered under this announcement.

Deadlines vary by project type.

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