Research Insights

Large Grant Opportunities

Sign up for the large grant opportunities and limited submissions listserv. The Office of Research hosts a listserv that shares large funding opportunities and internal competition announcements weekly as well as a calendar of current limited submissions opportunities.

DOE: Concentrating Solar Flux to Heat and Power Monday, April 15, 2024 - This FOA will help decarbonize the energy system and high-temperature industrial processes in the US through innovation and advancement in concentrating solar-thermal power technologies. Amount: $750,000 – $10,000,000 Due Date: 05/16/2024 (Concept Paper); 08/08/2024 (Full Proposal) More Information
NIH: Precision Mental Health: Develop Tools to Inform Treatment Selection in Depression (UG3/UH3 Clinical Trial Optional) Monday, April 15, 2024 - The purpose is to create a pipeline to accelerate the development and early validation of predictive tools and/or biomarkers to inform individual-level treatment selection among two or more existing therapeutics for depression. Amount: $12,835,000 Due Date: 09/18/2024 (LOI); 10/18/2024 (Full Proposal) More Information
NIH: Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional) Monday, April 15, 2024 - This program funds RDCRCs, which are intended to advance and improve diagnosis, management, and treatment of numerous, diverse rare diseases through highly collaborative, multi-site, patient-centric, translational, and clinical research. Amount: $7,550,000 Due Date: 07/12/2024 (LOI); 08/13/2024 (Full Proposal) MoreInformation
NIH: Cell and Gene Therapies for HIV Cure: Developing a Pipeline (P01 Clinical Trial Not Allowed) Monday, April 15, 2024 - This program supports multi-project research programs for the development, characterization, and advancement of gene- and cell-based approaches to achieve long-term remission or elimination of HIV. Applications should include basic science discovery as well as preclinical research activities. Amount: $16,610,000 Due Date: 06/30/2024 (LOI); 07/30/2024 (Full Proposal) More Information
NEH: Digital Projects for the Public Monday, April 15, 2024 - This program supports projects that interpret and analyze humanities content in primarily digital platforms and formats, such as websites, mobile applications and tours, interactive touch screens and kiosks, games, and virtual environments. Amount: $30,000 (Discovery); $100,000 (Prototyping); $400,000 (Production) Due Date: 05/01/2024 (Optional Draft); 06/12/2024 (Full Proposal) More Information
NIH: Tools and resources to understand the vascular pathophysiology of in vivo neuroimaging findings in ARIA (U24 – Clinical Trials Not Allowed) Wednesday, April 3, 2024 - This program promotes the development and distribution of innovative technologies, methods, protocols, and biomedical materials that enhance combined human neuropathology and neuroimaging research aimed at understanding the vascular pathogenesis and pathophysiology of anti-Aβ monoclonal antibody induced Amyloid Related Imaging Abnormalities. Amount: $7,550,000 Due Date: 04/30/2024 (LOI); 05/31/2024 (Full Proposal) More Information
NIH: Specialized Programs of Research Excellence (SPOREs) in Cancer Health Disparities and Minority Health (CHD-MH) (U54 Clinical Trial Optional) Wednesday, April 3, 2024 - This program will fund a network of multidisciplinary, multi-institutional SPOREs uniquely focused on health disparities and/or minority health translational research for improved prevention, early detection, diagnosis, and treatment of cancer in populations who are underserved and/or underrepresented. Amount: $12,080,000 Due Date: 08/26/2024 (LOI); 09/26/2024 (Full Proposal) More Information
NIH: Centers for Research in Emerging Infectious Diseases (CREID) Network Coordination Center (U01 Clinical Trial Not Allowed) Wednesday, April 3, 2024 - This program invites applications for the CREID Network Coordination Center to serve to lead, advance, facilitate, and coordinate critical and collaborative scientific, data and resource management, communication, and administrative activities during both outbreak and non-outbreak periods among the CREID Network research centers. Amount: $11,325,000 Due Date: 05/21/2024 (LOI); 06/21/2024 (Full Proposal) More Information
NIH: Centers for Research in Emerging Infectious Diseases (CREID) Network (U01 Clinical Trial Not Allowed) Wednesday, April 3, 2024 - Through this program, multi- and interdisciplinary teams of domestic and international investigators will conduct innovative, collaborative, hypothesis-driven One Health-based research, undertake outbreak-related research in their geographical areas, and work across the CREID Network. Amount: $6,417,500 Due Date: 05/21/2024 (LOI); 06/21/2024 (Full Proposal) More Information
NIH: AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional) Wednesday, March 27, 2024 - These Centers support innovative, interdisciplinary research in several areas, including basic, neuro-HIV, behavioral and social, biostatistics and data science, and integrated biobehavioral, clinical, translational, and implementation science. Amount: $11,325,000 Due Date: 07/25/2024 (LOI); 08/26/2024 (Full Proposal) More Information
NIH Director’s Pioneer Award Program (DP1 Clinical Trial Optional) Wednesday, March 27, 2024 - This program supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. Amount: $5,285,000 Due Date: 08/09/2024 (LOI); 09/09/2024 (Full Proposal) More Information
NIH: Nathan Shock Centers of Excellence in Basic Biology of Aging (P30 Clinical Trial Not Allowed) Wednesday, March 20, 2024 - These Center grants will provide funding for leadership, training, research, and outreach activities that will increase and disseminate scientific knowledge in areas supported by the NIA’s Division of Aging Biology. Amount: $8,305,000 Due Date: 05/15/2024 More Information
USDA: Agriculture and Food Research Initiative – Sustainable Agricultural Systems Wednesday, March 20, 2024 - This is USDA’s flagship competitive grant program and provides funding for fundamental and applied research, education, and extension projects in the food and agricultural sciences. Amount: $50,000 – $10,000,000 Due Date: 06/06/2024 More Information
NSF: Global Centers Wednesday, March 20, 2024 - This program funds international, interdisciplinary collaborative research centers that will apply best practices of broadening participation and community engagement to develop use-inspired bioeconomy research to address one or more global challenges identified by the scientific community. Amount: $5,000,000 Due Date: 06/11/2024 More Information
NEH: Cultural and Community Resilience Wednesday, March 20, 2024 - This program supports community-based efforts to address the impacts of climate change and COVID-19 by safeguarding cultural resources and fostering cultural resilience through identifying, documenting, and/or collecting cultural heritage and community experiences. Amount: $150,000 Due Date: 05/21/2024 More Information
NIH: Building Interdisciplinary Research Careers in Women’s Health (BIRCWH) (K12 Clinical Trial Optional) Monday, March 18, 2024 - This program supports mentored research career development of junior faculty members who have recently completed clinical training or postdoctoral fellowships, and who will be engaged in interdisciplinary basic, translational, data science, behavioral, clinical, and/or health services research relevant to the health of women and, where appropriate, the use of both sexes to better understand the […]
NSF: Ideas Lab: Advancing Cell-Free Systems Toward Increased Range of Use-Inspired Applications Monday, March 18, 2024 - This initiative will accelerate the adoption of cell-free systems, enable new applications of this technology and contribute to the growth of the U.S. bioeconomy. Amount: $11,250,000 Due Date: 05/17/2024 (Preliminary Proposal); 09/20/2024 (Full Proposal) More Information
NEH: Preservation and Access Education and Training Monday, March 18, 2024 - This program supports training that develops knowledge and skills among professionals responsible for preserving and establishing access to humanities collections. Amount: $350,000 Due Date: 04/09/2024 (Optional Draft); 05/21/2024 (Full Proposal) More Information
NEH: Research and Development Monday, March 18, 2024 - This program supports projects that address major challenges in preserving or providing access to humanities collections and resources. Amount: $100,000 (Tier 1); $350,000 (Tier 2) Due Date: 04/09/2024 (Optional Draft); 05/21/2024 (Full Proposal) More Information
NEH: Humanities Initiatives at Colleges and Universities Monday, March 18, 2024 - This program supports the development of new, or enhancement of existing, programs, educational resources, or courses that explore, interpret, and preserve the diversity of human cultures, ideas, and practices, past and present. Amount: $150,000 Due Date: 03/26/2024 (Optional Draft); 05/07/2024 (Full Proposal) More Information
NIH: Developing Digital Therapeutics for Substance Use Disorders (UG3/UH3 Clinical Trial optional) Monday, March 11, 2024 - The purpose of this program is to accelerate the development of Digital Therapeutics to treat Substance Use Disorders. Amount: $1,510,000 (UG3 Phase); Unspecified (UH3 Phase) Due Date: 06/17/2024 (LOI); 07/17/2024 (Full Proposal) More Information
NSF: Ideas Lab: Use-Inspired Acceleration of Protein Design Monday, March 11, 2024 - This program will accelerate the translation of novel approaches to protein design and enable new applications of importance to the U.S. bioeconomy. Amount: $3,750,000 Due Date: 04/23/2024 (Preliminary Proposal); 08/30/2024 (Full Proposal) More Information
NSF: Ideas Lab: Breaking the Low Latency Barrier for Verticals in Next-G Wireless Networks Monday, February 26, 2024 - The vision of this program is to support R&D that will dramatically reduce the E2E latencies cost-effectively to spur a great number of emerging vertical industries that will transform the way we live and interact with each other. Amount: $7,400,000 Due Date: 04/18/2024 (Preliminary Proposals); 09/30/2024 (Full Proposals) More Information
NSF: Multi-Messenger Coordination for Windows on the Universe Monday, February 26, 2024 - This one-time funding opportunity will support the development of frameworks and networks to optimize electromagnetic follow-up observations of gravitational wave events or high-energy particle detections. Amount: $1,500,000 – $2,500,000 Due Date: 05/13/2024 More Information
NIH: Consortium for Palliative Care Research Across the Lifespan (U54 Clinical Trial Optional) Monday, February 26, 2024 - This NOFO invites applications proposing the development of a specialized center to provide resources, expertise, and coordination to advance innovative, high-quality research on palliative care for those living with serious illnesses across the lifespan. Amount: $9,500,000 Due Date: 05/31/2024 (LOI); 07/02/2024 (Full Proposal) More Information
NSF: Accelerating Computing-Enabled Scientific Discovery (ACED) Monday, February 19, 2024 - This program seeks to harness computing to accelerate scientific discovery, while driving new computing advancements. The intent is to catalyze advancements that benefit scientific disciplines through computational technologies and foster novel computing technologies. Amount: $3,000,000 Due Date: 05/13/2024 (Track 1); 01/14/2025 (Track II) More Information
NSF: Sustainable Regional Systems Research Networks Wednesday, February 7, 2024 - The goal of this solicitation is to fund convergent research and education that will advance sustainable regional systems science, engineering, and education to facilitate the transformation of current regional systems to enhance sustainability. Amount: $15,000,000 Due Date: 05/14/2024 More information
High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional) Friday, January 26, 2024 - This opportunity supports high priority research at the intersection of HIV and substance use, and invites research projects with the potential to open new areas of basic and clinical HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use addictive substances. Amount: $11,325,000 Due Date: 08/15/2024 More […]
NEH: Dangers and Opportunities of Technology: Perspectives from the Humanities Thursday, January 18, 2024 - This program supports research that examines technology and its relationship to society through the lens of the humanities, with a focus on the dangers and/or opportunities presented by technology. NEH is particularly interested in projects that examine the role of technology in shaping current social and cultural issues Amount: $150,000 Due Date: 09/12/2024 More information
NIH: Research on the Impact of and Methods for Implementing Regional Genomic Medicine eConsult Services (U01 Clinical Trials Optional) Thursday, January 11, 2024 - This Notice of Funding Opportunity (NOFO) solicits applications for sites to conduct research on the impact of and methods for implementing regional clinician-to-clinician genomic medicine eConsult services. Amount: $7,353,700 Due Date: 04/30/2024 (LOI); 05/30/2024 (Full Proposal)  More information
NIH: Centers of Excellence for Translational Research (CETR) (U19 Clinical Trial Not Allowed) Wednesday, December 20, 2023 - This program will support multidisciplinary translational research Centers focused on generating, validating, and advancing medical countermeasures against bacteria or fungi listed in the NOFO with known and emerging resistance to current therapies. Amount: $37,750,000 Due Date: 03/29/2024 (LOI);04/30/2024 (Full Proposal) More information
NIH: NIDA Core “Center of Excellence” Grant Program (P30 Clinical Trial Optional) Wednesday, December 6, 2023 - This program enhances and extends existing research relevant to substance use/misuse and addiction and HIV. Centers are expected to transform the scientific field of study by facilitating research, providing administrative support and a rigorous research climate that promotes new and creative directions. Amount: Unspecified Due Date: 08/25/2024 (LOI); 09/25/2024 (Full Proposal) More Information
NEH: Dangers and Opportunities of Technology: Perspectives from the Humanities Thursday, November 9, 2023 - This program supports research that examines technology and its relationship to society through the lens of the humanities, with a focus on the dangers and/or opportunities presented by technology. NEH is particularly interested in projects that examine the role of technology in shaping current social and cultural issues. Amount: $150,000 Due Date: 09/12/2024 More Information
NIH: Individually Measured Phenotypes to Advance Computational Translation in Mental Health Wednesday, May 10, 2023 - Supports the work of the research projects funded under the Individually Measured Phenotypes to Advance Computational Translation in Mental Health (IMPACT-MH) initiative described in the companion announcement RFA-MH-23-105. Amount: $18,875,000 Due Date: 6/14/23 More Information
NSF: Synthesis Center for Understanding Organismal Resilience Wednesday, March 29, 2023 - Brings together communities that leverage existing data to catalyze discoveries through synthesis, analysis, and integrative training focusing on organisms as integrated units of biological organization i.e., why they are structured as they are and function as they do. Amount: $20,000,000 Due Date: 1/12/24 (preliminary proposal), 7/15/24 (full proposal) More Information
NEH: Digital Projects for the Public Wednesday, March 22, 2023 - This program supports projects that interpret and analyze humanities content in primarily digital platforms and formats, such as websites, mobile applications and tours, interactive touch screens and kiosks, games, and virtual environments. Amount: $400,000 Due Date: 6/14/23 More Information
NIH: Development of Novel Nonsteroidal Contraceptive Methods Tuesday, October 18, 2022 - Supports multidisciplinary research approaches for the development of novel nonsteroidal contraceptive products for men and women that act prior to fertilization. Amount: $3,020,000 Due Date: 3/29/23 More information
NIH: BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs Wednesday, March 16, 2022 - Supports interdisciplinary teams to elucidate the contributions of dynamic circuit activity to a specific behavioral or neural system.
NSF: Biodiversity on a Changing Planet (BoCP) Thursday, October 21, 2021 - The Biodiversity on a Changing Planet program is a cross directorate and international program led by NSF that invites submission of interdisciplinary proposals addressing grand challenges in biodiversity science within the context of unprecedented environmental change.
CDC: Vector-Borne Disease Regional Centers of Excellence Thursday, October 21, 2021 - The purpose of this NOFO is to support research to improve national capacity to address the growing problem of vector-borne diseases via continued support for regional Centers of Excellence for Vector-Borne Diseases.
NSF: Harnessing the Data Revolution (HDR): Transdisciplinary Research in Principles of Data Science Phase II (TRIPODS) Monday, October 18, 2021 - NSF's Harnessing the Data Revolution Big Idea is a national-scale activity to enable new modes of data-driven discovery that will allow fundamental questions to be asked and answered at the frontiers of science and engineering.
NSF: Computer and Information Science and Engineering (CISE) Community Research Infrastructure Program Monday, October 18, 2021 - The Computer and Information Science and Engineering Community Research Infrastructure program drives discovery and learning in the core CISE disciplines by funding the creation and enhancement of world-class research infrastructure.
NIH: Development of Microbiome-Related Approaches for Diagnosis/Mitigation/Treatment of Radiation Injuries (U01 Clinical Trial Not Allowed) Monday, October 11, 2021 - The purpose of this FOA is to support research that will advance the understanding of how the microbiome affects radiation injury.
DOC: US Marine Life Observations: Coordinated Marine Biodiversity Observation Network (MBON) and Animal Telemetry Network (ATN) Activities to Ensure Resilient, Productive Ecosystems and Human Communities in the Face of Change Monday, October 11, 2021 - This program supports proposals that: (1) build upon the foundation established by MBON, ATN and the US IOOS Regional Associations to work across sectors and disciplines towards an integrated, sustained marine life observing capability for the U.S. ocean, coasts and Great Lakes, from estuaries to the deep ocean.
NIH: Systems Biology for Infectious Diseases (U19 Clinical Trial Not Allowed) Monday, October 11, 2021 - The purpose of the FOA is to support research that employs systems biology approaches to human pathogens.
NIH: SPARC Human Open Research Neural Engineering Technologies (HORNET) Initiative (U41) Monday, October 11, 2021 - This U41 opportunity will fund centers to create interoperable open-source modules that can be combined into custom profiles for new exploratory and clinical neuromodulation studies in the peripheral nervous system, and for potential applicability in the central nervous system.
NIH: Pediatric Obesity Discovery Science Research to Improve Understanding of Risk and Causal Mechanisms for Obesity in Early Life (R01) Monday, October 11, 2021 - The purpose of this FOA is to support innovative, discovery research studies to better characterize early-life risk factors and elucidate underlying causal mechanisms through which these risk factors contribute to the development of obesity during infancy and early childhood.
NSF: Integrative Research in Biology (IntBIO) Saturday, September 25, 2021 - This solicitation invites submission of collaborative proposals that tackle bold questions in biology and require an integrated approach to make substantive progress.
NSF: Cyberinfrastructure for Sustained Scientific Innovation (CSSI) Saturday, September 25, 2021 - This solicitation expands the Cyberinfrastructure for Sustained Scientific Innovation program by adding a new project class: Transition to Sustainability.
NSF: Biology Integration Institutes (BII) Tuesday, September 21, 2021 - The NSF Directorate for Biological Sciences program for Biology Integration Institutes (BII) supports diverse and collaborative teams of researchers investigating questions that span multiple disciplines within and beyond biology.
NSF: EHR Core Research – Resource Coordination Hub (ECR Hub) Monday, September 13, 2021 - NSF seeks proposals to create an EHR Core Research (ECR) Resource Coordination Hub (ECR Hub) that will be an intellectual partner to the ECR:Core and the ECR:BCSER grantee communities and the NSF to enhance the overall influence and reach of ECR STEM education research investments.
DOE: Natural Gas Demand Response Pilot Program Monday, September 13, 2021 - FOA soliciting cooperative agreements for the development of multiple regional natural gas demand response pilot programs in collaboration with utilities, local distribution companies and public utility commissions.
NEH: Digital Humanities Advancement Grants Monday, September 13, 2021 - computationally challenging digital projects, leading to work that can scale to enhance scholarly research, teaching and public programming in the humanities.
NSF: Facility and Instrumentation Request Process (FIRP) Monday, September 13, 2021 - The Facility and Instrumentation Request Process (FIRP) solicitation describes the mechanism by which the research community can propose projects that require access to instrumentation and facilities sponsored by the FARE Program.
NIH: National Cancer Institute Youth Enjoy Science Research Education Program (R25) Friday, September 3, 2021 - This funding opportunity seeks to facilitate the education of students from diverse backgrounds underrepresented in biomedical research who will become knowledgeable about cancer, and available to focus on cancer later in their careers.