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Historical analysis of Salmonella using pre-existing data: trends in outbreaks, genomics, and geographic factors

We will evaluate the genetic changes of beef-related Salmonella isolates in the NCBI database, across time and geographic regions. The goal is to determine how quickly or slowly Salmonella populations change over time with respect to beef food safety and to identify patterns across time and geographic regions that could inform risks

1. Validation of a time period (“moving window”) over which to evaluate data for emergence of new outbreak Salmonella strains

2. Phylogeographic analysis of beef-related Salmonella outbreak case studies to identify factors contributing to disease emergence

3. Genomic analysis of historical and modern Salmonella isolates from top beef serovars to understand how pathogenicity evolves over time.

Funder: Meat & Poultry Research & Education

Amount: $122,630

PI: Nusrat “Nikki” Shariat, College of Veterinary Medicine