Research Matters

Large Grant Opportunities

Sign up for the large grant opportunities and limited submissions listserv. The Office of Research hosts a listserv that shares large funding opportunities and internal competition announcements weekly as well as a calendar of current limited submissions opportunities.

PCORI funding announcement opening moved to cycle 3 Friday, March 27, 2020 - PCORI funding announcement opening moves to June 9.
Limited Submission: Asthma and Allergic Diseases Cooperative Research Centers (U19 Clinical Trial Optional) Friday, March 27, 2020 - The purpose of this FOA is to invite applications from single institutions or consortia of institutions to participate in the Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program.
NIH: Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry – Study Sites (U01 Clinical Trial Not Allowed) Friday, March 27, 2020 - The goal of this FOA is to establish Centers for PRS Methods and Analysis for Populations of Diverse Ancestry to collaboratively generate and refine PRS for populations of diverse ancestry by integrating existing datasets with genomic and phenotype data for a range of complex diseases and traits.
NIH: Polygenic Risk Score (PRS) Methods and Analysis for Populations of Diverse Ancestry – Coordinating Center (U01 Clinical Trial Not Allowed) Friday, March 27, 2020 - The goal of this FOA is to establish a Coordinating Center for PRS Methods and Analysis for Populations of Diverse Ancestry.
NIJ: Longitudinal Research on Delinquency and Crime, Fiscal Year 2020 Friday, March 27, 2020 - Funding to conduct an expansion or extension of longitudinal research studies that focus on delinquency and crime throughout the life-course.
DOE: Joint FY20 Bioenergy and Advanced Manufacturing FOA BOTTLE: Bio-Optimized Technologies to keep Thermoplastics out of Landfills and the Environment Friday, March 20, 2020 - This FOA will support high-impact technology R&D to enable the development of technologies that overcome the challenges associated with plastic waste.
CDC: Expanding Efforts and Strategies to Protect and Improve Public Health in Vietnam Friday, March 13, 2020 - This NOFO seeks to build upon activities funded by CDC to support USG global health priorities in Vietnam through implementation of programs and activities that focus on strengthening public health programs.
NIH: NHGRI Technology Development Coordinating Center (U24 Clinical Trial Not Allowed) Friday, March 13, 2020 - This program will establish a Technology Development Coordinating Center for the National Human Genome Research Institute (NHGRI).
NIH: Exploring the use of Real-World Data to Generate Real-World Evidence in Regulatory Decision-Making (U01) Clinical Trials Optional Friday, March 13, 2020 - Supports research projects that examine real-world data (RWD), real-world evidence (RWE), and related issues such as data analytics, the use of digital health tools, and innovative trial designs utilizing healthcare settings.
NSF: Future Manufacturing (FM) Friday, March 6, 2020 - The goal of this solicitation is to support fundamental research and education of a future workforce that will enable Future Manufacturing.
DOE: Scientific Discovery through Advanced Computing: Scientific Machine Learning and Artificial Intelligence for Fusion Energy Sciences Friday, March 6, 2020 - The goal of this FOA is to support research aiming to sustain and enhance the leadership position of the United States in Artificial Intelligence (AI) while addressing high-priority research opportunities identified in recent fusion community studies.
CDC: Global Health Security Partnerships: Expanding and Improving Public Health Laboratory Strategies and Systems. Friday, March 6, 2020 - This NOFO is intended to support global health security partners to continue the implementation of laboratory activities that focus on protecting and improving public health globally.
DOD: CDMRP Peer Reviewed Medical Research Program Focused Program Award Friday, March 6, 2020 - This program is intended to optimize research and accelerate solutions to a critical question related to at least one of the Congressionally directed FY20 PRMRP Topic Areas through a synergistic, multidisciplinary research program.
DOD: CDMRP Peer Reviewed Medical Research Program Technology/Therapeutic Development Award Friday, March 6, 2020 - This program supports the translation of promising preclinical findings into products for clinical applications, including prevention, detection, diagnosis, treatment, or quality of life, in at least one of the Congressionally directed FY20 PRMRP Topic Areas.
NIH: Multidisciplinary Studies to Improve Understanding of Influenza Transmission (U19 Clinical Trial Optional) Friday, February 28, 2020 - The purpose of this FOA is to solicit applications for collaborative, multidisciplinary research to comprehensively investigate the dynamics and drivers of influenza transmission between humans.
NIH: National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental or Substance Use Disorders or Alcohol Disorder (U19 Clinical Trial Optional) Friday, February 28, 2020 - This FOA encourages applications to advance the discovery, preclinical development, and proof of concept testing of new, rationally based candidate agents and neurostimulation approaches to treat mental disorders, substance use disorders or alcohol use disorders, and to develop novel ligands and circuit-engagement devices as tools to further characterize existing or to validate new drug/device targets.
NIH: National Longitudinal Study of Adolescent to Adult Health (Add Health) Wave 6 (U01 Clinical Trial Not Allowed) Friday, February 28, 2020 - This FOA invites applications for the next 5-year cycle of the National Longitudinal Study of Adolescent to Adult Health (Add Health) to include a sixth wave of data collection (Wave VI).
NIH: Integrated Pathogen Reduction Technologies for whole blood and blood components for transfusion (R01) Clinical Trial Not Allowed Friday, February 21, 2020 - This program seeks to support the development of innovative pathogen reduction technologies for whole blood and blood components to prevent transfusion-transmitted infectious diseases.
NIH: Prodromal α-Synucleinopathies Consortium (PαSS) (U19 Clinical Trial Optional) Friday, February 21, 2020 - This FOA seeks to develop and support a consortium of investigators who will establish a common idiopathic REM sleep behavior disorder (iRBD) research protocol to collect and share harmonized clinical, cognitive, and biomarker data, establishing a centralized repository of biosamples from individuals with iRBD as they progress from prodromal α-synucleinopathy to Parkinson’s disease, Lewy Body Dementia, or Multi-System Atrophy.
DOE: Rapid Encapsulation of Pipelines Avoiding Intensive Replacement (REPAIR) Friday, February 21, 2020 - REPAIR seeks to develop the suite of technologies required to rehabilitate cast iron, wrought iron, and bare steel natural gas distribution pipes by developing technologies that will enable the automated construction of a new pipe inside the old pipe.
NIH: Network for Identification, Evaluation, and Tracking of Older Persons with Superior Cognitive Performance for Their Chronological Age (U19 Clinical Trial Not Allowed) Friday, February 21, 2020 - This FOA invites applications to establish a network to identify, evaluate, track, and conduct research across multiple sites on older adults with superior cognitive performance for their age.
(OPEN) Limited Submission: High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed) Thursday, February 20, 2020 - This program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-end, specialized, commercially available instruments or integrated systems.
NIH: Biological Measures for Prognosing and Monitoring of Persistent Concussive Symptoms in Early and Middle Adolescents: Center Without Walls (PCS-EMA CWOW) (U54 Clinical Trial Not Allowed) Friday, February 14, 2020 - This FOA is aimed at discovering, characterizing the selectivity and sensitivity, and externally validating biological measures to be used for assessing, prognosing, and monitoring recovery of adolescents who either clinically present with or are at risk for developing prolonged/persistent concussive symptoms following exposure to repetitive head impacts and/or concussion.
NIH: National Institute on Aging Genetics of Alzheimer’s Disease Data Storage Site (U24 Clinical Trial Not Allowed) Friday, February 14, 2020 - This FOA invites applications specific to infrastructure that will support the storage, analysis, and sharing of primary and secondary data for the genetics and genomics of Alzheimer's disease and Alzheimer's disease-related dementias.
NIH: Biomedical Technology Development and Dissemination Center (RM1 – Clinical Trial Not Allowed) Friday, February 7, 2020 - This program supports the development of technologies once their feasibility has been established and the dissemination of these technologies to the wider biomedical research community.
NIH: National Cancer Institute Program Project Applications (P01 Clinical Trial Optional) Friday, January 31, 2020 - Applications are accepted for investigator-initiated Program Projects that address any of the broad areas of cancer research, including (but not limited to) cancer biology, cancer prevention, cancer diagnosis, cancer treatment, and cancer control.
NIJ: Research and Evaluation of Promising Reentry Initiatives, Fiscal Year 2020 Friday, January 24, 2020 - The goal of this solicitation is to advance the body of knowledge on promising practices in offender reentry, in part to inform federal and other reentry-specific initiatives.
NIH: Genomic Community Resources (U24 Clinical Trial Not Allowed) Friday, January 24, 2020 - This FOA will support the development and distribution of genomic resources that use cost-effective approaches and will be valuable for the broad research community.
DOE: FY20 Bioenergy Technologies Multi-Topic FOA Friday, January 24, 2020 - This FOA will provide funding to address Bioenergy Technologies Office’s highest priority R&D areas.
HHS: UT2 Autism Intervention Research Network on Physical Health (AIR-P) Friday, January 17, 2020 - The purpose of this program is to establish and maintain an interdisciplinary, multicenter research platform for scientific collaboration and infrastructure building.
HHS: UT3 Autism Intervention Research Network on Behavioral Health Friday, January 17, 2020 - The purpose of this program is to establish and maintain an interdisciplinary, multicenter research platform for scientific collaboration and infrastructure building.
NIH: NIA Research Centers Collaborative Network (RCCN) (U24 Clinical Trial Optional) Friday, December 6, 2019 - The purpose of this FOA is to support a network to enhance collaborations across NIA's 6 centers programs.
USAID: The Health, Ecosystems and Agriculture for Resilient, Thriving Societies (HEARTH) Friday, December 6, 2019 - The Office of Forestry and Biodiversity is seeking transformational solutions to cross-sectoral development challenges in biodiverse landscapes.
NSF: Cyberinfrastructure Centers of Excellence (CI CoE) Thursday, November 7, 2019 - Supports hubs of expertise and innovation targeting specific areas, aspects, or stakeholder communities of the research CI ecosystem.
NEH: Digital Humanities Advancement Grants Friday, November 1, 2019 - These Grants support innovative, experimental, and/or computationally challenging projects at different stages throughout their lifecycles, from early start-up phases through implementation and sustainability.
NIH: Informatics Technology for Cancer Research Education Center (UE5 Clinical Trials Not Allowed) Thursday, September 19, 2019 - This FOA establishes an ITCR Education Center to provide education resources that will enhance the use and usability of the informatics tools and resources developed and supported by the ITCR program.
NIH: NIDDK Cooperative Centers of Excellence in Hematology (U54 Clinical Trial Not Allowed) Friday, September 13, 2019 - The program is designed to increase access to critical research resources and collaboration in the national multidisciplinary research effort to combat nonmalignant hematologic diseases and to study normal hematopoiesis.
NSF: Long-Term Ecological Research (LTER): New Urban Site Monday, August 12, 2019 - The LTER program has long recognized the importance of humans in ecological systems and is especially interested in how human activities in urban settings interact with natural processes to determine ecological outcomes.
NEH: Digital Humanities Advancement Grants Wednesday, April 24, 2019 - DHAG supports digital projects at different stages throughout their lifecycles, from early start-up phases through implementation and sustainability.
NSF: Sustained Availability of Biological Infrastructure Monday, April 1, 2019 - The SABI supports the continued operation of extant infrastructure that will advance basic biological research.