Great Commitments, Great Faculty
Georgia Research Alliance Eminent Scholars are acknowledged leaders in areas of science that are strategically important to the state of Georgia and its research universities. They hold endowed chairs made possible by the Georgia Research Alliance, a unique nonprofit that grows Georgia’s economy by expanding university research and entrepreneurship. GRA’s investment and involvement generate more discoveries, more startup companies and more high-value jobs in Georgia. The public-private alliance invests State of Georgia funds, and its operations are supported by corporations, individuals and foundations.
Working with their colleagues across the university, GRA Eminent Scholars have helped the University of Georgia rise 41% in research and development expenditures from fiscal year 2013 to 2020.
Georgia Research Alliance
Eminent Scholars at
the University of Georgia
Norman and Doris Giles/GRA Eminent Scholar in Molecular Biology and Functional Genomics
Year Recruited: 2003 | Previous Institution: Purdue University
Bennetzen is translating insights about the genomes of cereals and other grasses into knowledge that can increase crop yields for food and biofuels. His discoveries include the genetic basis of why plant genomes vary more than 1,000-fold in DNA content, which is known as the C-value paradox. His honors include two Fulbright Awards, a Guggenheim Fellowship and election to the National Academy of Sciences.
- Cloned and sequenced the first transposable elements from plants
- Created the first genetic map of sorghum
GRA Eminent Scholar in Drug Design
Year Recruited: 2019 | Previous Institution: Wayne State University
Crich is pursuing the design of novel aminoglycoside antibiotics for the treatment of ESKAPE pathogens, six bacterial pathogens commonly associated with multidrug resistance. He aims to expand into carbohydrate-based areas, developing glycomimetics—therapeutic agents that mimic carbohydrates—for use in drug design.
- Developed new glycosylation methods and is known for seminal contributions to the elucidation of the principles of reactivity and selectivity
- Co-founded the biotech startup Juvabis AG to develop next-generation antibiotics for the treatment of multidrug resistant infectious diseases/span>
GRA Eminent Scholar in Molecular Cell Biology
Director, Center for Molecular Medicine
Year Recruited: 2002 | Previous Institution: University of Adelaide
Dalton is unlocking the potential of non-embryonic stem cells to replace damaged cells in the body and help grow new, healthy tissue. His research is furthering the basic understanding of developmental processes in stem cells and applying them to conditions ranging from cardiovascular disease to diabetes and neurological disorders.
Created the first blueprint of how stem cells are wired to respond to signaling molecules
Developed a cell-based therapeutic that provides new hope for diabetes patients
Distinguished Research Professor
Barbara and Sanford Orkin/GRA Eminent Scholar in Emerging Diseases and Cellular Biology
Year Recruited: 2005 | Previous Institution: University of Illinois Urbana-Champaign
Docampo is developing new therapies to treat parasitic diseases such as sleeping sickness. His lab has identified a specific cellular process within the parasite that can be disrupted and is now using this knowledge to develop drugs that attack the parasite without harming the human host.
Discovered that the parasite that causes Chagas disease is susceptible to a common class of antifungal compounds
Discovered a previously unknown organelle that is a promising drug target
GRA Eminent Scholar of Nuclear Magnetic Resonance Spectroscopy
Year Recruited: 2015 | Previous Institution: University of Florida
Edison has pioneered new techniques and instrumentation to advance the field of metabolomics, which is focused on small molecules called metabolites that are essential to life.
Metabolomics has the potential to give scientists the ability to obtain a comprehensive snapshot of a person’s health, opening up new avenues for diagnosing illnesses.
Developed new approaches for the identification of metabolites and established a large center for metabolomics
Illuminated the role that small metabolic products play in communication among animals
GRA Eminent Scholar in Biomedical Glycoscience
Year Recruited: 2015 | Previous Institution: Stony Brook University
Haltiwanger is shedding light on how cells communicate and applying this knowledge to the development of new drugs. His work has led to the identification of several novel drug targets, and he and his colleagues are now applying their research to cancer, congenital heart defects and other developmental disorders.
Discovered several novel drug targets for cancer and developmental disorders
Identified important roles for complex carbohydrates in communication between cells
William Henry Terry Sr./GRA Eminent Scholar in Drug Discovery
Year Recruited: 2018 | Previous Institution: Johns Hopkins University
Hart and his colleagues discovered a unique sugar that is attached to many proteins and alters their function in response to nutrients and blood glucose levels. Later studies revealed that this complex carbohydrate plays a role in diabetes, cancer and degenerative diseases such as Alzheimer’s. Hart and his team are currently working to translate this knowledge into improved diagnostic tests.
Discovered a complex carbohydrate involved in diabetes, cancer and neurodegenerative diseases
Developed a new early detection method for diabetes
GRA Eminent Scholar in Antiparasitic Drug Discovery
Director, Center for Tropical and Emerging Global Diseases
Year Recruited: 2017 | Previous Institution: University of South Florida
Kyle is one of the world’s top experts on malaria and other parasitic diseases, and his research is fueling the discovery of powerful new medicines. He also discovered a new way to grow human liver cells in the laboratory, enabling more effective testing of malaria drug candidates.
Identified two promising new anti-malarial drugs as part of international teams
Developed two new drug candidates to treat brain-eating amoebae infections
ROBERT J. MAIER
Ramsey/GRA Eminent Scholar in Microbial Physiology
Year Recruited: 1998 | Previous Institution: Johns Hopkins University
Maier has shown that some human pathogenic bacteria, including some associated with cancers, are able to use hydrogen produced as a consequence of normal intestinal flora as an energy source for growth. His lab is now working to understand how pathogens survive in this harsh environment, with the goal of identifying potential drug targets.
Discovered that H. pylori, which causes 90% of all gastric cancers, can use hydrogen as an energy source
lluminated the processes that bacteria use to metabolize hydrogen
GRA Eminent Scholar in Drug Discovery
Year Recruited: 2002 | Previous Institution: University of Iowa
Nair discovered an entirely novel class of HIV integrase inhibitors directed at “the point of no return” in HIV infectivity. Subsequent preclinical studies revealed no adverse treatment–related findings from clinical pathology or clinical chemistry parameters. In addition, preclinical studies revealed that some of these integrase inhibitors had significant therapeutic potential against multidrug-resistant tuberculosis.
Discovered a new class of anti-HIV drugs
Developed drug candidates against fatal HIV/ multidrug-resistant tuberculosis co-infection
Charles Wheatley Chair/GRA Eminent Scholar in Immunology and Translational Biomedicine
Year Recruited: 2016 | Previous Institution: University of Pittsburgh
Norris’ work is focused on the mechanisms of opportunistic infections, which pose serious risks to people with weakened immune systems. In addition to informing new vaccines and therapies, her research also is yielding new knowledge on how the natural aging process, as well as chronic diseases such as HIV, can weaken the immune system.
Led the development of a vaccine to protect against Pneumocystis pneumonia
Established animal models for Pneumocystis pneumonia, chronic obstructive pulmonary disease and pulmonary arterial hypertension
GRA Eminent Scholar in Magnetic Resonance Spectroscopy, Emeritus
Year Recruited: 1998 | Previous Institution: Yale University
An essential part of developing any new drug is determining how that drug will bind to the protein it is targeting, a process that begins with characterizing the structures and shapes of interacting molecules. Prestegard is a leader in using nuclear magnetic resonance (NMR) spectroscopy to do exactly that.
Developed new NMR-based methods that extend the range of applicability of the technology
Revealed new insights into membrane- and carbohydrate-linked proteins that regulate cellular interactions
GRA Eminent Scholar in Infectious Diseases
Director, Center for Vaccines and Immunology
Year Recruited: 2015 | Previous Institution: Vaccine and Gene Therapy Institute of Florida
Ross is leading a 15-institution team from around the country in a National Institutes of Health initiative to develop a new, more advanced influenza vaccine designed to protect against multiple flu strains with a single dose. Awarded in September 2019 and supported by up to $130 million over seven years, the project will focus initially on those populations most vulnerable to flu infection, including small children, the elderly and the immuno-compromised.
Developed technology to design vaccine candidates against influenza, dengue and HIV
Pioneered the use of C3d, a component of the innate immune system, to boost the effectiveness of vaccines
GRA Eminent Scholar in Regenerative Medicine
Director, Regenerative Bioscience Center
Year Recruited: 1998 | Previous Institution: University of Massachusetts
Stice looks at the cells in his lab and imagines a hundred possible uses for them: repairing damaged tissue, detecting dangerous substances and creating disease-resistant animals, just to name a few examples. Stice has founded four Georgia companies to commercialize the technologies developed in his lab. Among them is ArunA Biomedical, which has developed proprietary neural exosomes that can be used to treat neurodegenerative diseases.
Awarded the world’s first patent for therapeutic cloning from adult cells
First-to-market innovation: Methods of using exosomes for treatment of spinal cord injury, stroke and traumatic brain injury
GRA Eminent Scholar in Vaccine and Therapeutic Studies
Year Recruited: 2004 | Previous Institution: Centers for Disease Control and Prevention
Tripp is translating discoveries on immunity and pathogenesis into new treatments for respiratory diseases and new methods that speed vaccine development. His discoveries have led to the development of antiviral drugs for influenza as well as for RSV, a flu-like virus that can be fatal in young children and the elderly. He is the founder and chief scientific officer of two startup companies—Proventus Bio and Hypercell.
Developed anti-viral drugs for influenza and RSV
Discovered new methods for augmenting vaccine expression
CHUNG-JUI “C.J.” TSAI
Winfred N. “Hank” Haynes/GRA Eminent Scholar in Forest Biotechnology
Year Recruited: 2008 | Previous Institution: Michigan Technological University
Tsai imagines a day when trees are a prime source of biofuel. To make that day a reality, she’s working to design better, hardier trees with higher biomass yields. Using modern genomic tools, she is mapping out ways to accelerate tree growth, make trees more drought resistant and spur them to produce more biomass.
Pioneered the application of CRISPR genome-editing technology to forest trees
Identified genes that mediate how trees respond to stresses such as drought
Ramsey/Georgia Research Alliance Eminent Scholar in Structural Biology
Founding Director, SER-CAT
Year Recruited: 1995 | Previous Institution: University of Pittsburgh
Wang has transformed the field of X-ray crystallography and its use in drug development. He founded a consortium of 25 institutions known as SER-CAT (for Southeast Regional Collaborative Access Team) that has produced data on more than 3,900 protein structures that have been deposited in the Protein Data Bank.
Developed more efficient and cost-effective techniques for X-ray crystallography
Part of teams that determined the protein structures of eukaryotic and prokaryotic model organisms C. elegans and P. furiosus
Georgia Research Alliance Eminent Scholar in Bioinformatics
Year Recruited: 2003 | Previous Institution: Oak Ridge National Laboratory
Xu is a computational biologist who uses a portfolio of computational tools, such as the large-scale mining of biological data. Unlike most cancer researchers, who study cultures derived from cancerous cells, Xu and his team analyze genetic data derived from tissues. Their techniques have uncovered important information about how cancer begins.
Developed a model that describes how chronic inflammation and hypoxia can lead to cell proliferation and cancer
Developed a urine test to diagnose gastric cancer
Georgia Research Alliance
By partnering with the state’s research universities, the Georgia Research Alliance helps recruit nationally and internationally recognized scientists in areas of strategic importance to the state of Georgia and its economy.
GRA also accelerates the launch and growth of university enterprises through its venture development program and invests in research-driven, Georgia-based startup companies through the GRA Venture Fund.
To learn more, visit gra.org
University of Georgia
With the support of nonprofit partners such as the Georgia Research Alliance, federal and state agencies, and private foundations, the University of Georgia is making strides in research that advances its three Great Commitments:
- Healthier People
- A More Secure Future
- Stronger Communities