{"id":1693,"date":"2024-09-25T19:27:48","date_gmt":"2024-09-25T19:27:48","guid":{"rendered":"https:\/\/research.uga.edu\/team-research\/?post_type=projects&p=1693"},"modified":"2024-09-25T19:27:48","modified_gmt":"2024-09-25T19:27:48","slug":"mechanisms-and-drivers-of-inflammatory-bowel-diseases","status":"publish","type":"projects","link":"https:\/\/research.uga.edu\/team-research\/projects\/mechanisms-and-drivers-of-inflammatory-bowel-diseases\/","title":{"rendered":"Mechanisms and Drivers of Inflammatory Bowel Diseases"},"content":{"rendered":"

[vc_row][vc_column][vc_column_text css=”.vc_custom_1727292448368{margin-top: 0px !important;margin-left: 0px !important;padding-top: 0px !important;padding-left: 0px !important;}”]<\/p>\n

Teaming for Interdisciplinary Research Pre-Seed Program<\/span><\/h1>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row bg_type=”bg_color” css=”.vc_custom_1578688250197{margin-right: 0px !important;padding-right: 0px !important;}”][vc_column width=”1\/2″ css=”.vc_custom_1578688242468{background-color: #004e60 !important;}”][vc_column_text css=”.vc_custom_1595866319329{margin-left: 10px !important;padding-bottom: 10px !important;}”]<\/p>\n

Mechanisms and Drivers of Inflammatory Bowel Diseases<\/span><\/h3>\n

[\/vc_column_text][\/vc_column][vc_column width=”1\/2″ css=”.vc_custom_1578686850507{background-color: #ffffff !important;border: 10px initial !important;}”][vc_single_image image=”201″ img_size=”full” alignment=”right” onclick=”link_image” css=”.vc_custom_1578688163679{margin-bottom: 0px !important;padding-bottom: 0px !important;}”][\/vc_column][\/vc_row][vc_row css=”.vc_custom_1578666495607{margin-top: 10px !important;}”][vc_column][vc_row_inner][vc_column_inner width=”2\/3″][vc_empty_space][vc_column_text]Inflammatory bowel diseases (IBD), such as Crohn\u2019s disease and colitis, have become urgent public health concerns, affecting 1.6 million Americans with an additional 70,000 new cases each year. IBD are lifelong conditions, marked by chronic inflammation of the intestinal tract, abdominal pain, diarrhea, weight loss, and other debilitating symptoms. Currently, the complex mechanisms behind IBD, and the reasons for their increasing prevalence in developed countries, are poorly understood. As a result, treatments for IBD remain limited, mostly confined to anti-inflammatory drugs and biologics, which have multiple negative side effects and to which patients may develop resistance. Most patients eventually require highly invasive surgery to remove inflamed intestinal tissue, which still does not cure the underlying disease. This interdisciplinary group has been assembled to address the critical research gaps surrounding IBD. Through our efforts, we aim to improve our collective understanding of IBD, their genetic and environmental origins, and identify new therapeutic targets to treat patients with these conditions. Our long-term goal is to develop effective, safe therapies for IBD that would drastically improve patient qualities of life.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=”1\/3″][vc_column_text]<\/p>\n

Team Lead<\/h4>\n

Rob Pazdro<\/strong>
\nDepartment of Foods and Nutritions
\nrpazdro@uga.edu<\/a><\/p>\n

Team Members<\/h4>\n

Claire de la Serre<\/strong>
\nDepartment of Foods and Nutrition<\/p>\n

Emily Noble<\/strong>
\nDepartment of Foods and Nutrition<\/p>\n

Kaori Sakamoto<\/strong>
\nDepartment of Pathology<\/p>\n

Wendy Watford<\/strong>
\nDepartment of Infectious Diseases<\/p>\n

Kaixiong Ye<\/strong>
\nDepartment of Genetics[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"featured_media":0,"menu_order":0,"template":"","format":"standard","meta":{"_links_to":"","_links_to_target":""},"categories":[],"class_list":["post-1693","projects","type-projects","status-publish","format-standard","hentry"],"_links":{"self":[{"href":"https:\/\/research.uga.edu\/team-research\/wp-json\/wp\/v2\/projects\/1693"}],"collection":[{"href":"https:\/\/research.uga.edu\/team-research\/wp-json\/wp\/v2\/projects"}],"about":[{"href":"https:\/\/research.uga.edu\/team-research\/wp-json\/wp\/v2\/types\/projects"}],"version-history":[{"count":0,"href":"https:\/\/research.uga.edu\/team-research\/wp-json\/wp\/v2\/projects\/1693\/revisions"}],"wp:attachment":[{"href":"https:\/\/research.uga.edu\/team-research\/wp-json\/wp\/v2\/media?parent=1693"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/research.uga.edu\/team-research\/wp-json\/wp\/v2\/categories?post=1693"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}