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(OPEN) Limited Submission: Martin Delaney Collaboratory for Pediatric HIV Cure Research (UM1 Clinical Trial Not Allowed)

This Funding Opportunity Announcement is soliciting applications to support research on HIV cure in pediatric populations.

Summary

This Funding Opportunity Announcement (FOA) is soliciting applications to support research on HIV cure in pediatric populations. This FOA will support coordinated basic, clinical, and applied research focused on developing strategies to achieve an HIV cure, defined as either sustained viral remission or eradication of HIV infection. The cure of HIV infection in people living with HIV is one of the highest priorities of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH). The goal of the Martin Delaney Collaboratory program is to accelerate progress towards developing strategies to achieve either eradication of HIV infection from the body or a sustained viral remission, as defined by sustained viral suppression following cessation of antiretroviral therapy. Funded projects under this FOA will be expected to expand the knowledge base on HIV latency and persistence in pediatric populations, design and evaluate innovative cure strategies, develop and evaluate assays and other modalities to accurately characterize HIV reservoirs and translate findings to the clinical settings. This funding opportunity will target perinatally infected children and adolescents and young adults up to 24 years of age with a primary focus on early treated children.

Please read the full program announcement before preparing your internal application.

Award Amount

  • Application budgets are limited to $3.5M in direct costs per year and need to reflect the actual needs of the proposed project.
  • The total project period must be 5 years.

Eligibility

  • Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.
  • Only one application per institution (normally identified by having a unique DUNS number or NIH IDF number) is allowed to either this FOA or the companion FOA for the adult Martin Delaney Collaboratories for HIV Cure Research (RFA-AI-20-035) . An institution may not submit one application to this FOA and one application to the adult MDC FOA. However, a given institution may receive funds through subawards from more than one application.

Selection Criteria

Detailed review criteria can be found here.

Limitation Details

An Institution may submit one proposal to either this FOA or the companion FOA for the adult Martin Delaney Collaboratories for HIV Cure Research (RFA-AI-20-035) . An institution may not submit one application to this FOA and one application to the adult MDC FOA. However, a given institution may receive funds through subawards from more than one application.

If you are interested in submitting for this program, you must first submit an internal application to limsub@uga.edu according to the required instructions below.

Internal Applications must include the following:

  • A cover page listing
    • The name of this funding opportunity and title of your proposal
    • Your name, UGA position, home department, email, and UGA contact information
    • Collaborator names, positions, and institutions (if any)
    • Indicate whether or not you have submitted to this program in the past. If so, please provide a copy of the review at the end of the internal application.
  • A (maximum two-page) proposal summary that addresses the program’s specific selection criteria.
  • One paragraph describing why this proposal should be UGA’s submission (i.e., why it will be the most competitive for this program)
  • Curriculum vitae

Internal Selection

Limited Submission announcements often generate multiple competing proposals.  UGA reviewers judge proposals as they would in any peer review process, so PIs are urged to put their best foot forward.  Along with typical criteria, reviewers will evaluate internal proposals based on their fit with the sponsor’s articulated goals and criteria.

Internal Submission Instructions

The above internal application materials should be submitted via email as a single .PDF file to limsub@uga.edu by the internal deadline listed above.

Questions?

Please submit questions regarding the internal competition to limsub@uga.edu.

For questions directly related to this program, please contact the following program officers:

Tania B. Lombo, Ph.D.
National Institute of Allery and Infectious Diseases (NIAID)
Telephone: 301-761-7612
Email: tania.lombo@nih.gov

Eric Lorenzo, Ph.D.
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Telephone: 301-443-4993
Email: eric.lorenzo@nih.gov

Vasundhara Varthakavi, D.V.M., Ph.D.
National Institute on Drug Abuse (NIDA)
Telephone: 301-443-2146
Email: vasundhara.varthakavi@nih.gov

Jeymohan Joseph, Ph.D.
National Institute of Mental Health (NIMH)
Telephone: 240-627-3869
E-mail: jjeymoha@mail.nih.gov

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