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Research Matters

Limited Submission: Emerging Infections Network – Research for Preventing, Detecting, and Managing Travelers who Acquire Infectious Diseases Abroad

The purpose of this program is to support research activities that will assist with the prevention, detection, and management of international travelers who become ill during or after travel.

Summary

The purpose of this notice of funding opportunity (NOFO) is to support research activities that will assist with the prevention, detection, and management of international travelers who become ill during or after travel. The project must have a focus on travel and tropical medicine providers with the capability to participate in both research and surveillance to determine the disease prevention strategies, burden, severity, optimal diagnostics, treatment interventions, and outcomes of infectious diseases acquired by travelers while abroad. This research will bridge the gap between clinical medicine and public health by assisting with improving patient care, better understanding the natural history of disease, and implementing optimal diagnostic and treatment strategies, with the ultimate outcome being an advancement in the global health security of the United States.

Please read the full program announcement before preparing your internal application.

Award Amount

  • Estimated total funding available for the first year (first 12-month budget period), including direct and indirect costs: $1,500,000
  • Estimated total funding available for the entire five (5)-year project period, including direct and indirect costs: $7,500,000

Eligibility

  • Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Project Director/Principal Investigator (PD/PI) is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and 17 of 48 ethnic groups as well as individuals with disabilities are always encouraged to apply for HHS/CDC support.
  • As defined in the HHS Grants Policy Statement, (https://www.hhs.gov/sites/default/files/grants/grants/policies-regulations/hhsgps107.pdf), applications received in response to the same Notice of Funding Opportunity generally are scored individually and then ranked with other applications under peer review in their order of relative programmatic, technical, or scientific merit. HHS/CDC will not accept any application in response to this NOFO that is essentially the same as one currently pending initial peer review unless the applicant withdraws the pending application.

Selection Criteria

Significance: Does the project address an important problem or a critical barrier to progress in the field? If the aims of the project are achieved, how will scientific knowledge, technical capability, and/or clinical practice be improved? How will successful completion of the aims change the concepts, methods, technologies, treatments, services, or preventative interventions that drive this field?

  • Does the work address a scientific problem of great importance to public health research and/or practice?
  • Will the work be influential in that it will lead others to investigate the problem, open new areas of research, or change the scientific approach or public health practice, and how will this improve and be of value to public health?

Investigator(s): Are the PD/PIs, collaborators, and other researchers well suited to the project? Have they demonstrated an ongoing record of accomplishments that have advanced their field(s)? If the project is collaborative or multi-PD/PI, do the investigators have complementary and integrated expertise; are their leadership approach, governance and organizational structure appropriate for the project?

  • Do the investigators have a successful track record in public health research?
  • Is there evidence of past collaborations among the proposed research team?

Innovation: Does the application challenge and seek to shift current research or clinical practice paradigms by utilizing novel theoretical concepts, approaches or methodologies, instrumentation, or interventions? Are the concepts, approaches or methodologies, instrumentation, or interventions novel to one field of research or novel in a broad sense? Is a refinement, improvement, or new application of theoretical concepts, approaches or methodologies, instrumentation, or interventions proposed?

  • Is the proposed research innovative and yet offer reasonable potential for concrete applications of interest and value to public health?

Approach: Are the overall strategy, methodology, and analyses well-reasoned and appropriate to accomplish the specific aims of the project? Are potential problems, alternative strategies, and benchmarks for success presented? If the project is in the early stages of development, will the strategy establish feasibility and will particularly risky aspects be managed? If the project involves clinical research, are there plans for 1) protection of human subjects from research risks, and 2) inclusion of minorities and members of both sexes/genders, as well as the inclusion of children, justified in terms of the scientific goals and research strategy proposed?

  • Does the application propose to use evidence-based interventions or strategies in the research plan?
  • If the project is in the latter stages of development, will the strategy establish scalability?
  • In the Evaluation and Performance Measurement plan, are outputs identified and are measures/metrics to assess outcomes included?

Environment: Will the scientific environment in which the work will be done contribute to the probability of success? Are the institutional support, equipment and other physical resources available to the investigators adequate for the project proposed? Will the project benefit from unique features of the scientific environment, subject populations, or collaborative arrangements?

  • Does the project support key stakeholder involvement throughout the research process?

Limitation Details

An Institution may submit one proposal.

If you are interested in submitting for this program, you must first submit an internal application to limsub@uga.edu according to the required instructions below.

Internal Applications must include the following:

  • A cover page listing
    • The name of this funding opportunity and title of your proposal
    • Your name, UGA position, home department, email, and UGA contact information
    • Collaborator names, positions, and institutions (if any)
    • Indicate whether or not you have submitted to this program in the past. If so, please provide a copy of the review at the end of the internal application.
  • A (maximum two-page) proposal summary that addresses the program’s specific selection criteria.
  • One paragraph describing why this proposal should be UGA’s submission (i.e., why it will be the most competitive for this program)
  • Curriculum vitae

Internal Selection

Limited Submission announcements often generate multiple competing proposals.  UGA reviewers judge proposals as they would in any peer review process, so PIs are urged to put their best foot forward.  Along with typical criteria, reviewers will evaluate internal proposals based on their fit with the sponsor’s articulated goals and criteria.

Internal Submission Instructions

The above internal application materials should be submitted via email as a single .PDF file to limsub@uga.edu by the internal deadline listed above.

Questions?

Please submit questions regarding the internal competition to limsub@uga.edu.

For questions directly related to this program, please contact the following program officers:

Amy Yang, Ph.D.

1600 Clifton Road, MS US8-1 Atlanta, GA 30333

Telephone: 404-718-8836

Email: AYang@cdc.gov


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