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2022 NIH Director’s Pioneer Award (DP1 – Clinical Trial Optional): RFA-RM-21-015

The NIH Director’s Pioneer Award in the High-Risk, High-Reward Research program provides unique opportunities for exceptionally creative scientists to pursue highly innovative approaches to address major challenges in biomedical or behavioral research.

The NIH Common Fund announces the FY2022 funding opportunity for the NIH Director’s Pioneer Award in the High-Risk, High-Reward Research program. The program provides unique opportunities for exceptionally creative scientists to pursue highly innovative approaches to address major challenges in biomedical or behavioral research. Any research topic relevant to the broad mission of NIH is welcome. NIH especially encourages applications from women and members of groups that are underrepresented in NIH-funded research.

2022 NIH Director’s Pioneer Award (DP1 – Clinical Trial Optional): RFA-RM-21-015

Supports scientists with outstanding records of creativity proposing pioneering approaches to major challenges in any area of science relevant to the broad mission of NIH. Individuals from diverse backgrounds and from the full spectrum of eligible institutions in all geographic locations are strongly encouraged to apply to this Funding Opportunity Announcement. In addition, applications in all topics relevant to the broad mission of NIH are welcome, including, but not limited to, topics in the behavioral, social, biomedical, applied, and formal sciences and topics that may involve basic, translational, or clinical research.

  • Open to all career stages
  • Single-PI applications only
  • No preliminary data required
  • Must be new scientific research direction
  • $700,000 direct costs per year for 5 years
  • Application deadline: Sept. 10, 2021

See the Pioneer Award website for more information, including FAQs, an application guide with a sample application, and past webinar (a new webinar will be forthcoming).

The High-Risk High-Reward Research Program and other Common Fund programs are managed by the Office of Strategic Coordination, Division of Program Coordination, Planning, and Strategic Initiatives in the NIH Office of the Director, in partnership with the component NIH Institutes, Centers, and Offices. The NIH Common Fund encourages collaboration and supports a series of exceptionally high impact, trans-NIH programs.

The National Institutes of Health includes 27 institutes and centers and is a component of the U. S. Department of Health and Human Services. It is the primary federal agency for conducting and supporting basic, clinical and translational medical research, and it investigates the causes, treatments and cures for both common and rare diseases. For more information, visit the NIH website.