{"id":25301,"date":"2023-01-24T16:28:59","date_gmt":"2023-01-24T21:28:59","guid":{"rendered":"https:\/\/research.uga.edu\/research-insights\/?page_id=25301"},"modified":"2023-01-25T09:05:35","modified_gmt":"2023-01-25T14:05:35","slug":"notable-grants","status":"publish","type":"page","link":"https:\/\/research.uga.edu\/research-insights\/notable-grants\/","title":{"rendered":"Notable Grants"},"content":{"rendered":"<div class=\"wpb-content-wrapper\">[vc_row][vc_column][vc_column_text]<div class=\"display-posts-listing\"><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/machine-learning-guided-sequence-manipulation-for-tailored-spatial-gene-regulation-in-plants\/\">Machine learning-guided sequence manipulation for tailored spatial gene regulation in plants\u00a0<\/a> <span class=\"date\">Thursday, May 14, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Single-cell analyses have uncovered diverse cell-type-specific features, yet how cis-regulatory elements (CREs) encode spatial expression patterns in plants remains poorly understood. To address this gap, we will establish a CRISPRbased perturbation platform in soybean hairy roots that uses base editors, error-prone polymerases, and helicases to generate dense local sequence variants, coupled with single-cell multiomic profiling. [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/molecular-determinant-of-age-related-cognitive-decline-in-the-basal-forebrain-to-lateral-entorhinal-cortex-circuit\/\">Molecular Determinant of Age-Related Cognitive Decline in the Basal Forebrain to Lateral Entorhinal Cortex Circuit<\/a> <span class=\"date\">Thursday, May 14, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">The entorhinal cortex (EC) is a critical mediator of cortico-hippocampal communication and thus essential for memory. Numerous studies identify the EC as the first brain region to display age-related changes such as accumulation of tau protein as related to Alzheimer\u2019s disease (AD). Structural and functional changes to the EC have been found to precede and [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/mitigating-the-risk-of-abiotic-stress-damage-in-blueberry-production-through-pangenome-graph-based-genotyping-and-phenomics-approaches\/\">Mitigating The Risk\u00a0Of\u00a0Abiotic Stress Damage\u00a0In\u00a0Blueberry Production Through Pangenome Graph-Based Genotyping\u00a0And\u00a0Phenomics Approaches\u00a0<\/a> <span class=\"date\">Thursday, May 14, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Blueberry production in the US is threatened by spring freeze damage and summer heat stress. Addressing these issues aligns with the AFRI legislative priority to &#8220;Genetically dissect and introduce desirable traits to improve plant\u2019s tolerance to temperature extremes associated with climate change&#8221;. Warm spring temperatures promote early blooms which elevates the risk of early freeze [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/cesu-piedmont-estimating-population-size-and-spatial-distribution-of-the-south-georgia-black-bear-population-2\/\">CESU Piedmont: Estimating population size and spatial distribution of the South Georgia black bear population\u00a0<\/a> <span class=\"date\">Thursday, May 14, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">This effort will produce accurate and contemporary population estimates for the South Georgia bear population (SGP). Such an estimate will allow for an evaluation of how current and future proposed harvest rates will impact the SGP. Data collection will include genetic hair-snare sampling and camera-trapping efforts. Analyses will be supplemented by GPS spatial data collected [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/georgia-rural-enhancement-and-transformation-of-health-great-health-program\/\">Georgia Rural Enhancement\u00a0And\u00a0Transformation of Health (GREAT Health) Program\u00a0<\/a> <span class=\"date\">Thursday, May 14, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">This project will assist the Department of Community Health (DCH) in strengthening the disaster resilience of Georgia\u2019s rural hospitals, skilled nursing facilities (SNFs), and inpatient hospice facilities through the Emergency Preparedness \u2013 Shelter in Place Initiative as part of the Georgia Rural Health Transformation (GREAT) Program. Our collaborative efforts aim to address one of DCH\u2019s [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/data-guided-workload-distribution-to-improve-icu-patient-outcomes-and-healthcare-worker-well-being\/\">Data-Guided Workload Distribution to Improve ICU Patient Outcomes and Healthcare Worker Well-Being<\/a> <span class=\"date\">Monday, April 20, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Healthcare worker (HCW) workload is a modifiable factor with strong relationships to both HCW well-being and patient safety. Team-based care is the gold standard for the treatment of critically ill patients in the intensive care unit (ICU). The robust body of evidence suggests that high workloads in the ICU are significant drivers of medication errors [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/secoora-real-time-monitoring-of-right-whales-using-gliders\/\">SECOORA Real Time Monitoring of Right Whales Using Gliders<\/a> <span class=\"date\">Monday, April 20, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">The goal of this proposal is to invest in the capacity and infrastructure of the Southeast Coastal Ocean Observing Regional Association (SECOORA) glider observatory to develop, test, and implement autonomous passive acoustic monitoring of North Atlantic right whales in the South Atlantic Bight (SAB). Critically endangered North Atlantic right whales experience high mortality rates due [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/the-als-institute-building-the-capacity-of-grades-5-12-urban-educators-to-deliver-high-quality-culturally-responsive-instruction\/\">The ALS Institute: Building the Capacity of Grades 5-12 Urban Educators to Deliver High Quality &amp; Culturally Responsive Instruction<\/a> <span class=\"date\">Monday, April 20, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">The Urban Agriculture and Life Sciences Summer Institute will build the capacity of urban educators to recruit and retain the next generation of urban agriculturalists by increasing engagement, knowledge acquisition, and knowledge retention of students using culturally responsive practices. For this project, 36 middle and high school educators will be selected to participate in a [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/novel-immunoprophylaxis-strategies-for-antigen-and-nanobody-delivery-to-combat-avian-influenza\/\">Novel Immunoprophylaxis Strategies for Antigen and Nanobody Delivery to Combat Avian Influenza<\/a> <span class=\"date\">Monday, April 20, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">The purpose of this co-operative agreement is to develop a two-pronged immunoprophylactic strategy for the prevention and control of highly pathogenic avian influenza (HPAI) in poultry. We aim to develop a rapid and cost-effective immunotherapeutic designed to protect highly susceptible young chicks and to be deployed during emergency outbreaks. In parallel, we will also develop [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/engineered-synthetic-low-density-lipoprotein-nanoparticles-for-enhanced-cancer-immunotherapy-in-head-and-neck-cancer\/\">Engineered Synthetic Low-Density Lipoprotein Nanoparticles for Enhanced Cancer Immunotherapy in Head and Neck Cancer<\/a> <span class=\"date\">Monday, April 20, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide. Despite technological advancements, the 5-year survival rate for advanced HNSCC has remained stagnant for the past three decades. The FDA has approved immune checkpoint inhibitors (ICIs), including pembrolizumab and nivolumab, for the treatment of recurrent and metastatic HNSCC. While immunotherapy can [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/multiscale-measurement-of-o-glcnac-changes-in-parkinsons-disease\/\">Multiscale measurement of O-GlcNAc\u00a0changes in Parkinson\u2019s Disease\u00a0<\/a> <span class=\"date\">Thursday, March 12, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Drugs that increase O-GlcNAc have been developed and proceeded into clinical trials. Notably, O-GlcNAc is found on neurodegeneration associated proteins, like tau and \u03b1-Syn, and has been shown to inhibit their amyloid aggregation and associated pathology in vitro and in mouse models. However, little is known concerning any differences in O-GlcNAc levels in PD versus [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/collaborative-research-unveiling-the-molecular-mechanism-of-feeding-tube-formation-by-root-knot-nematodes-structural-and-functional-insights\/\">Collaborative Research: Unveiling the molecular mechanism of feeding tube formation by root-knot nematodes: structural and functional insights\u00a0<\/a> <span class=\"date\">Thursday, March 12, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">There is an urgent agricultural need for novel approaches to combat the billions of dollars lost annually to the devastating root-knot nematode, an obligate sedentary endoparasite and global threat to food and fiber crop production. The focus of this project is to resolve the mystery of the root-knot nematode feeding tube, a unique nematode-produced structure [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/anti-highly-pathogenic-avian-influenza-hpai-effects-of-tannins-in-poultry\/\">Anti-Highly Pathogenic Avian Influenza (HPAI) effects of tannins in poultry<\/a> <span class=\"date\">Thursday, March 12, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">The purpose of this cooperative agreement is to evaluate the antiviral therapeutic potential of tannins against highly pathogenic avian influenza (HPAI) as natural anti-viral supplements and immunomodulators in poultry. Tannins, plant-derived polyphenolic compounds and their metabolites, have highly effective antiviral effects against broad spectrums of pathogenic viruses including influenza virus H3N2, H5N3, herpes simplex virus-1, [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/harnessing-the-power-of-nutrition-against-avian-influenza\/\">Harnessing the Power of Nutrition against Avian Influenza\u00a0<\/a> <span class=\"date\">Thursday, March 12, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">By integrating innovative biotechnology and a comprehensive understanding of viral-host interactions, this approach aims to significantly mitigate the threat of highly pathogenic avian influenza (HPAI) in poultry through oral prophylaxis. This agreement evaluates the potential of natural compounds, alone and in combination, as immunomodulators and antivirals against HPAI. We will test each compound and compound [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/mass-vaccination-ready-reassortment-impaired-live-virus-vaccines-against-highly-pathogenic-avian-influenza\/\">Mass vaccination-ready, reassortment-impaired live virus vaccines against Highly Pathogenic Avian Influenza\u00a0<\/a> <span class=\"date\">Thursday, March 12, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Driven by the urgent need to safeguard the US poultry industry from the devastating impact of Highly Pathogenic Avian Influenza (HPAI), this project leverages a powerful synergy between the University of Georgia&#8217;s cutting-edge research capabilities and the established industrial expertise of CEVA Animal Health and BioStone Animal Health to deliver a transformative solution: the first [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/population-modeling-of-american-alligators-to-inform-harvest-management-and-future-research-in-georgia\/\">Population Modeling of American Alligators to Inform Harvest Management and Future Research in Georgia<\/a> <span class=\"date\">Tuesday, February 17, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">American alligators (Alligator mississippiensis) are managed quite differently than most other fish and wildlife species in the United States. As reptiles, they do not fall within the \u2018fur and feathers\u2019 category traditional to state wildlife management, which typically receives the bulk of attention, management, and funding. Despite harvest in aquatic habitats, they are also not [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/physiological-and-molecular-regulation-of-fruit-ripening-in-blueberry\/\">Physiological And Molecular Regulation of Fruit Ripening in Blueberry<\/a> <span class=\"date\">Tuesday, February 17, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Fruit ripening is a highly regulated developmental process. From a human diet perspective, fruit are a reservoir of antioxidants and vitamins. Until recently, a few fruits have served as model systems to investigate mechanisms associated with fruit ripening. However, aspects of ripening physiology and their regulation by transcription factors and hormones are fruit-specific, and show [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/an-integrated-basic-and-translational-approach-to-mitigate-key-enteric-diseases-of-poultry\/\">An Integrated Basic and Translational Approach to Mitigate Key Enteric Diseases of Poultry<\/a> <span class=\"date\">Tuesday, February 17, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">The objectives of this project are to: 1. Investigate the mechanisms of pathogenicity of Eimeria field isolates that cause poultry coccidiosis and assess the bird responses to infections. The team will (1) propagate and harvest pure cultures of Eimeria isolates to obtain high quality DNA for generating full genome sequences of Eimeria parasites; (2) test [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/improving-sustainable-management-of-southern-pine-forests-optimizing-productivity-resilience-trade-offs-under-combined-drought-fire-and-pathogen-stress\/\">Improving Sustainable Management of Southern Pine Forests: Optimizing Productivity-Resilience Trade-Offs Under Combined Drought, Fire, and Pathogen Stress<\/a> <span class=\"date\">Tuesday, February 17, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Global forests are increasingly at risk from multiple, synergistic stressors, threatening both timber production and ecosystem services. While trade-offs between productivity and resilience are well-documented, studies investigating belowground stress response mechanisms are limited, particularly for long-lived tree species. Furthermore, the genetic basis of these traits and the degree to which genetic co-associations may constrain adaptation [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/culture-and-community-at-the-penn-center\/\">Culture and Community at the Penn Center<\/a> <span class=\"date\">Tuesday, February 17, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">The Penn School for Culture and Community is in the first instance a partnership between the Penn Center National Historic Landmark District and the University of Georgia\u2019s Willson Center for Humanities &amp; Arts. This partnership has led to a series of other collaborations, with other institutions, communities, and foundations. These have intersected in turn with [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/alfalfa-is-for-beef-cattle\/\">Alfalfa IS for Beef Cattle\u00a0<\/a> <span class=\"date\">Thursday, January 15, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">This proposal spans three years with combined efforts from three universities representing three states in the Eastern region (University of Georgia, Auburn University, and Clemson University). This proposal addresses USDA Strategic Plan priority areas by providing opportunities for American agriculture producers to be competitive in the marketplace, provide a safe, nutritious food product, and expand [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/trilateral-fpp-2023-homoeolog-aware-gene-networks-at-single-cell-resolution-to-improve-cold-tolerance-in-wheat\/\">Trilateral FPP 2023 &#8211;\u00a0Homoeolog-aware gene networks at single-cell resolution to improve cold tolerance in wheat\u00a0<\/a> <span class=\"date\">Thursday, January 15, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Climate change is causing unpredictable and severe winter weather, which can devastate wheat crops in major growing regions like Europe, North America, and China. Sudden cold snaps or warm spells during winter can reduce wheat yields by up to 50%, posing a major challenge for farmers and food production worldwide. Wheat, like many staple crops, [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/new-wild-species-derived-pest-and-disease-resistances-for-the-southeast-of-the-usa-2025\/\">New wild species-derived pest and disease resistances for the Southeast of the USA \u2013 2025\u00a0<\/a> <span class=\"date\">Thursday, January 15, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Cultivated peanut has an exceptionally narrow genetic base. This imposes limitations on the improvements that can be made by breeding with peanuts of pure pedigree, in particular with regard to pest and disease resistance. Here we propose to continue the work of incorporation of new pest and disease resistances from wild species into agronomically elite [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/high-throughput-biochemical-nuclear-magnetic-resonance-and-computational-predictive-biology-to-decode-glycosyltransferases-of-unknown-function-in-sorghum-bicolor\/\">High-throughput biochemical, nuclear magnetic resonance, and computational predictive biology to decode glycosyltransferases of unknown function in Sorghum bicolor\u00a0<\/a> <span class=\"date\">Thursday, January 15, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Plants supply essential nutrients, fibers, and pharmaceuticals vital for human survival, and raw materials for numerous industries, including bioenergy, which supports jobs and drives economic development. Glycosyltransferases (GTs) catalyze the formation of glycosidic linkages to produce complex carbohydrates, which are highly abundant in all plants. This project will use high-throughput (HTP) biochemical, biophysical, and computational [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/impact-of-breastmilk-on-campylobacter-jejuni-survival\/\">Impact of breastmilk on Campylobacter\u00a0jejuni survival<\/a> <span class=\"date\">Thursday, January 15, 2026<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Campylobacter jejuni is a major cause of bacterial-induced diarrhea worldwide. Infection leads to high rates of morbidity and mortality in low-and-middle income countries (LMICs), particularly in young children where up to 85% of infants are C. jejuni stool positive by one year of age. Also, post-infectious complications such as GuillainBarr\u00e9 syndrome, irritable bowel syndrome, reactive [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/characterization-of-brown-spot-needle-blight-resistance-in-radiata-pine\/\">Characterization of Brown Spot Needle Blight Resistance in Radiata Pine<\/a> <span class=\"date\">Monday, December 15, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Brown spot needle blight (BSNB), caused by Lecanosticta acicola, is a foliar disease affecting several species of pines and is a major concern for many commercial plantations globally. The use of host resistance is a promising avenue to mitigate the damage caused by the disease, however, little has been done to characterize resistance and facilitate [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/discovering-and-deploying-genetic-solutions-across-maturity-groups-for-durable-resistance-to-multiple-nematodes-2\/\">Discovering and Deploying Genetic Solutions across Maturity Groups for Durable Resistance to Multiple Nematodes<\/a> <span class=\"date\">Monday, December 15, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Nematodes are among the top yield-robbers encountered by soybean farmers across the U.S. Almost all soybean cyst nematode (SCN)-resistant varieties in U.S. soybean production are derived from two genetic sources, imposing risk of genetic vulnerability and resistance breakdown. Soybean breeders and growers are limited in genetic sources for nematode resistance with competitive yield, which places [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/virtual-risks-and-hero-projects-activating-transformative-community-actions-for-climate-resilience-against-extreme-weather-events-through-extended-reality-and-artificial-intelligence\/\">Virtual Risks and Hero Projects: Activating Transformative Community Actions for Climate Resilience Against Extreme Weather Events through Extended Reality and Artificial Intelligence<\/a> <span class=\"date\">Monday, December 15, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">This project leverages assets from a previously funded NOAA project and the research team\u2019s expertise in using immersive technologies to translate critical hazardous weather information with these theory-driven and evidence-based objectives: (1) amplify the impact of risk communication through mixed-reality (MR) simulations of hazardous weather events (hurricane, wildfire) that can localize the experience of risk [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/developing-lg007-as-a-novel-therapeutic-agent-to-treat-triple-negative-breast-cancer\/\">Developing LG007 as a Novel Therapeutic Agent to Treat Triple Negative Breast Cancer<\/a> <span class=\"date\">Monday, December 15, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">For women in the United States, breast cancer is the most common malignancy and the second leading cause of death. In this application, we focus upon a specific subtype of breast cancer known as triple-negative breast cancer (TNBC). Compared to other breast cancer subtypes, TNBC is considered more aggressive and extremely difficult to treat with [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/wild-species-genetics-conquer-pests-and-diseases-limiting-groundnut-production-in-africa-and-beyond\/\">Wild Species Genetics Conquer Pests and Diseases Limiting Groundnut Production in Africa and Beyond<\/a> <span class=\"date\">Monday, December 15, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Groundnut (Arachis hypogaea L.) is the world&#8217;s second most produced grain legume and a critically important crop in Africa, particularly for small-scale producers and communities in the drylands. This crop represents a subsistence protein source for smallholder farming families and an affordable nutrition source in global markets, as well as a source of cash to [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/iucrc-phase-i-university-of-georgia-center-for-innovation-in-risk-catastrophes-and-decisions-circad\/\">IUCRC Phase I University of Georgia: Center for Innovation in Risk, Catastrophes, and Decisions (CIRCAD)\u00a0<\/a> <span class=\"date\">Tuesday, November 18, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Duke University and the University of Georgia (UGA) propose an Industry-University Collaborative Research Center (IUCRC) called the Center for Innovation in Risk-analysis for Climate Adaptation and Decision-making (CIRCAD). CIRCAD will be an interdisciplinary, high-impact research center that integrates climate science and engineering, data science and modeling, risk assessment and decision theory, and economic and policy [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/collective-behavior-of-oscillators-in-fungal-filaments-of-neurospora-crass-clock\/\">Collective behavior of oscillators in fungal filaments of Neurospora crass (Clock)\u00a0<\/a> <span class=\"date\">Tuesday, November 18, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">A grand challenge is how cellular clocks in organisms, tissues, and cells become synchronized. The focus here will be initially on understanding the synchronization of cellular clocks in filaments in a model fungal system, Neurospora crassa. The core clock mechanism genes wc-1, wc-2, and frq have homologs in flies and mammals but are in single [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/advancing-gene-functional-analyses-adaptation-and-regeneration-in-upland-and-lowland-switchgrass-via-single-cell-genomics\/\">Advancing Gene Functional Analyses, Adaptation, and Regeneration in Upland and Lowland Switchgrass via Single-Cell Genomics\u00a0<\/a> <span class=\"date\">Tuesday, November 18, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Switchgrass, a C4 grass native to the US, is a high-yielding cellulosic bioenergy feedstock. Lowland switchgrass ecotypes produce high biomass yields but are largely cold-sensitive, which hinders expansion of their cultivation into Northern US regions where the lower yielding, but cold-tolerant upland ecotype is grown. Extensive efforts are dedicated to the rapid domestication of switchgrass, [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/doe-center-for-plant-and-microbial-complex-carbohydrates\/\">DOE Center for Plant and Microbial Complex Carbohydrates\u00a0<\/a> <span class=\"date\">Tuesday, November 18, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">This DOE Center renewal proposal will focus on structure, biosynthesis, and function of the plant cell wall polysaccharide rhamnogalacturonan-I (RG-I), a major ubiquitous and structurally complicated pectic polysaccharide that exists in the cell walls of all vascular plants. Plant biomass is an abundant renewable resource for the production of carbon-based bioproducts, chemicals, and glycomaterials. However, [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/genipins-ecm-crosslinking-action-as-an-agent-to-prevent-neurodegeneration-in-familial-dysautonomia\/\">Genipin\u2019s\u00a0ECM Crosslinking Action as an Agent to Prevent Neurodegeneration in Familial Dysautonomia\u00a0<\/a> <span class=\"date\">Tuesday, November 18, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Familial Dysautonomia (FD) is a severe genetic disorder affecting children, with no specific treatment. It involves neurodevelopmental defects at birth and progressive sensory and autonomic neuropathy. Symptoms include progressing loss of pain and temperature sensation, gait ataxia, and blindness. FD is caused by a mutation in the ELP1 gene, reducing the Elp1 protein in peripheral [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/chromosome-specific-meiotic-biology\/\">Chromosome-specific meiotic biology<\/a> <span class=\"date\">Monday, October 20, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Meiosis is a tightly controlled process during which the diploid genome must segregate into haploid gametes (e.g. eggs or sperm). Inheritance of the incorrect number of chromosomes is a leading cause of fertility and birth defects. However, the reasons for chromosome missegregation are not always the same for all chromosomes. Why inter-chromosomal differences exist is [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/expanding-seeds-of-success-support-and-ground-truthing-provisional-seed-transfer-zones-through-genetic-analysis\/\">Expanding Seeds of Success Support and Ground-Truthing Provisional Seed Transfer Zones Through Genetic Analysis<\/a> <span class=\"date\">Monday, October 20, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">This project, funded by the Bipartisan Infrastructure Law &#8211; Burned Area Recovery (BIL-BAR), will support the national native seed collection program, Seeds of Success (SOS), in its efforts to develop native plant materials for stabilizing, rehabilitating, and restoring post-wildfire lands. The award establishes the U.S. Forest Service\u2019s (USFS) National Seed Laboratory (NSL) in Dry Branch, [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/navigating-the-transition-to-middle-age-in-the-strong-african-american-healthy-adults-project-shape\/\">Navigating the Transition to Middle Age in the Strong African American Healthy Adults Project (SHAPE)<\/a> <span class=\"date\">Monday, October 20, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">African Americans in the rural South are often not included in studies focused on the developmental origins of cognitive decline and cardiometabolic disease, but they experience among the lowest life expectancies in the US among the lowest life expectancies in the US, a consequence of morbidity from chronic diseases of aging (CDAs) and Alzheimer\u2019s disease [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/using-2d-and-3d-adrenal-gland-tissues-to-investigate-developmental-and-disease-paradigms\/\">Using 2D and 3D adrenal gland tissues to investigate developmental and disease paradigms<\/a> <span class=\"date\">Monday, October 20, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">The adrenal glands are vital endocrine organs, comprising the medulla and cortex, that control stress responses, metabolism, blood pressure, and immunity. We hypothesize that better understanding of medulla and cortex development, their interaction and pathologies will unlock novel treatment options for adrenal gland disorders. Our long-term goal is to use human pluripotent stem cell (hPSC)-derived [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/national-stem-teacher-corps-pilot-program-ga-elevating-science-teachers-excellence-everyday-dmm1-matters-ga-esteem\/\">National STEM Teacher Corps Pilot Program: GA-Elevating Science Teachers\u2019 Excellence Everyday [DMM1]\u00a0Matters (GA-ESTEEM)<\/a> <span class=\"date\">Monday, October 20, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">The National STEM Teacher Corps Pilot Program: Georgia \u2013 Elevating Science Teachers\u2019 Excellence Everyday Matters (GA-ESTEEM) project will address the critical need to elevate Georgia\u2019s K-12 science teachers who have demonstrated excellence in teaching science and strengthen the work of new and existing science teachers. This five-year project will build alliances among professional organizations, state [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/merging-bacteriophage-biology-with-microbial-glycobiology\/\">Merging bacteriophage biology with microbial glycobiology<\/a> <span class=\"date\">Monday, September 22, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Bacteriophages, or phages, are considered the most abundant organisms on Earth with an estimated 10+31 particles in the biosphere. These viruses are in a perpetual arms race with bacteria and arguably the major force driving bacterial evolution. Similarly, phages continue to develop novel mechanisms to infect their host and avoid detection, and carbohydrates are central [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/retrospective-marsh-model-comparison-study\/\">Retrospective Marsh Model Comparison Study<\/a> <span class=\"date\">Monday, September 22, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Coastal marsh environments exist at the intersection of human populations and the ocean. They provide economic output through commercial fisheries, tourism, and recreation and protect coastal communities during storm events. Coastal land managers and other stakeholders need vetted scientific information and user-driven tools to understand salt marshes&#8217; vulnerability and to make informed decisions on management [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/molecular-mechanism-of-mfs-and-mop-lipid-transporters-in-cell-wall-biosynthesis\/\">Molecular mechanism of MFS and MOP lipid transporters in cell wall biosynthesis<\/a> <span class=\"date\">Monday, September 22, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Transporters from the multidrug exporter\/oligosaccharidyl-lipid\/polysaccharide (MOP) superfamily and the major facilitator superfamily (MFS) are central to multiple cell wall biopolymer biosynthesis pathways. Transporters from both superfamilies exhibit significant differences in their architecture, lipid substrate selectivity, and transport mechanisms. There are several critical gaps in our current understanding of the molecular mechanism of substrate recognition and [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/memory-regulatory-t-cells-in-recurring-malaria\/\">Memory Regulatory T cells in Recurring Malaria<\/a> <span class=\"date\">Monday, September 22, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Regulatory T cells or \u2018Tregs\u2019 play a critical role in our health and well-being by suppressing over- exuberant immune responses. Antigen-specific Tregs, like other T cell subsets, are maintained for prolonged periods in the host as memory Tregs (mTregs). These are possibly recalled to protect against the immunopathology associated with repeated encounters with the same [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/lter-georgia-coastal-ecosystems-v\/\">LTER: Georgia Coastal Ecosystems \u2013 V<\/a> <span class=\"date\">Monday, September 22, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">The Georgia Coastal Ecosystems (GCE) Long Term Ecological Research (LTER) program, which was established in 2000 to understand estuaries (places where salt water from the ocean mixes with fresh water from the land) and their adjacent coastal wetlands (i.e., marshes and tidal forests) and how they respond to long-term change. The GCE LTER researchers evaluate [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/multi-tracer-investigation-of-hydraulic-connectivity-between-the-okefenokee-swamp-and-the-upper-floridan-aquifer\/\">Multi-Tracer Investigation of Hydraulic Connectivity between the Okefenokee Swamp and the Upper Floridan Aquifer<\/a> <span class=\"date\">Monday, August 18, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">We propose to investigate whether water from the Okefenokee Swamp flows into the underlying Upper Floridan Aquifer\u2014a key source of drinking water for communities in southern Georgia and northern Florida. While past studies hinted at a possible connection, no one has directly compared the swamp\u2019s water with nearby groundwater using modern scientific tools. This project [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/between-relativism-and-reproach-exploring-value-judgements-about-good-human-lives-within-theologically-engaged-anthropology\/\">Between Relativism and Reproach: Exploring Value Judgements about Good Human Lives within Theologically Engaged Anthropology<\/a> <span class=\"date\">Monday, August 18, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">This project addresses the Big Question: how can anthropologists and theologians responsibly navigate the extremes of relativism and unreflexive judgmentalism to support good human lives? While both disciplines have explored the concept of good human lives, a collaborative approach is urgently needed to tackle the analytical challenges posed by relativism, which can devolve into amoral [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/characterizing-chemsex-or1-patterns-and-adoption-of-harm-reduction-measures-among-men-in-the-south\/\">Characterizing chemsex [OR1]\u00a0patterns and adoption of harm reduction measures among men in the South<\/a> <span class=\"date\">Monday, August 18, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Chemsex is a practice of drug use before or during sexual activity to facilitate, enhance, prolong, and sustain sexual pleasure. The drugs that are most commonly used in chemsex include crystalized methamphetamine (crystal meth), gamma-hydroxybutyrate (GHB), gamma-butyrolactone (GBL), mephedrone, amyl nitrite, ketamine, and ecstasy\/MDMA. They are chosen for their disinhibition effects on the common social, [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/plasmodium-effectors-mitigating-cell-intrinsic-immune-responses-in-hepatocytes\/\">Plasmodium effectors mitigating cell-intrinsic immune responses in hepatocytes<\/a> <span class=\"date\">Monday, August 18, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Malaria is a serious disease caused by the parasite Plasmodium, which initially infects liver cells before spreading to red blood cells and causing a potentially lethal infection. Traditionally, this early liver stage was considered to be relatively invisible to the immune system. However, recent studies, including our own, have found that liver cells can detect [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/career-composition-transport-and-fate-of-dissolved-and-pyrogenic-organic-matter-in-fire-impacted-soils\/\">CAREER: Composition, transport, and fate of dissolved and pyrogenic organic matter in fire-impacted soils<\/a> <span class=\"date\">Monday, August 18, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">This project will advance our understanding of soil processes that control the amount of carbon stored in soil. Understanding the controls on soil carbon storage and loss are critical for managing our natural environment for plant productivity, for improving our water quality, and for mitigating the effects of anthropogenic climate change. This project involves a [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/confronting-racial-inequity-with-black-history-the-development-and-initial-validation-of-a-measure-of-black-history-consciousness-for-african-descent-youth\/\">Confronting Racial Inequity with Black History: The Development and Initial Validation of a Measure of Black History Consciousness for African Descent Youth\u00a0<\/a> <span class=\"date\">Tuesday, July 15, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Black history has been identified as important to psychosocial adjustment and education outcomes. In K\u201212 and in higher education settings, Black history supports transformational educational experiences whereby African descent students can more readily negotiate race-based discrimination and develop counternarratives that challenge deficit ideas about their abilities as students and their value as people. Despite growing [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/pinpoint-the-sox10-taste-bud-progenitor-cells-in-von-ebners-glands-and-sox10-regulation-in-cell-differentiation\/\">Pinpoint the Sox10+ taste bud progenitor cells in von Ebner&#8217;s glands and Sox10 regulation in cell differentiation\u00a0<\/a> <span class=\"date\">Tuesday, July 15, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">In mammals, taste bud cells are post-mitotic, and they have a short lifespan and undergo continuous renewal, therefore, progenitors in the immediate surrounding tissue must be available to renew taste bud cells for homeostasis. Thorough information of taste bud progenitors and molecular regulation in the cell differentiation is essential to understanding taste disorders caused by [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/development-and-standardization-of-a-novel-pituitary-adenoma-organoid-model-for-the-study-and-treatment-of-cushings-disease\/\">Development and Standardization of a Novel Pituitary Adenoma Organoid Model for the Study and Treatment of Cushing&#8217;s Disease\u00a0<\/a> <span class=\"date\">Tuesday, July 15, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Cushing\u2019s disease (CD) is a serious endocrine disorder characterized by an adrenocorticotropic hormone (ACTH)-secreting PitNET that subsequently stimulates the adrenal glands to overproduce cortisol. Chronic exposure to excess cortisol has wide ranging and detrimental effects on health, including increased stroke rates, diabetes, obesity, depression, anxiety and death. Although CD is linked to a threefold increase [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/rural-pharmacy-harm-reduction-model\/\">Rural Pharmacy Harm Reduction Model<\/a> <span class=\"date\">Tuesday, July 15, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Despite the implementation of numerous successful harm reduction programs across the state, accessing harm reduction services remains a challenge for those living in rural communities. This lack of proximity to resources can directly impact the outcomes for those at risk of an opioid overdose. Our proposal seeks to utilize an untapped healthcare resource currently available [&hellip;]<\/span><\/div><div class=\"listing-item\"><a class=\"title\" href=\"https:\/\/research.uga.edu\/research-insights\/evolution-of-retrotransposon-control-mechanisms\/\">Evolution of Retrotransposon Control Mechanisms\u00a0<\/a> <span class=\"date\">Tuesday, July 15, 2025<\/span> <span class=\"excerpt-dash\">-<\/span> <span class=\"excerpt\">Dysregulated expression of retrotransposons and other transposable elements (TEs) can lead to increases in TE copy number, DNA damage and instability, or aberrant regulation of host genes, which in turn can contribute to human disease. Conversely, TE activity is required for processes ranging from early mammalian development and cell senescence to horizontal transposon transfer (HTT) [&hellip;]<\/span><\/div><\/div>[\/vc_column_text][\/vc_column][\/vc_row]\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text][\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"author":114,"featured_media":0,"parent":0,"menu_order":36,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-25301","page","type-page","status-publish","hentry"],"publishpress_future_action":{"enabled":false,"date":"2026-05-21 12:55:43","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/research.uga.edu\/research-insights\/wp-json\/wp\/v2\/pages\/25301","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/research.uga.edu\/research-insights\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/research.uga.edu\/research-insights\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/research.uga.edu\/research-insights\/wp-json\/wp\/v2\/users\/114"}],"replies":[{"embeddable":true,"href":"https:\/\/research.uga.edu\/research-insights\/wp-json\/wp\/v2\/comments?post=25301"}],"version-history":[{"count":0,"href":"https:\/\/research.uga.edu\/research-insights\/wp-json\/wp\/v2\/pages\/25301\/revisions"}],"wp:attachment":[{"href":"https:\/\/research.uga.edu\/research-insights\/wp-json\/wp\/v2\/media?parent=25301"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}