NIH has revised the instructions for applications with due dates beginning Jan. 25, 2019, to clarify the “Scientific Premise” review criterion, NOT-OD-18-228. This criterion has been re-named “Rigor of the Prior Research,” and NIH instructions have been revised to clarify the meaning as the strengths and weaknesses in the prior research that serve as the key support for the proposed project. Investigators are further instructed to describe plans to address weaknesses in the rigor of the prior research within the Research Strategy of applications. Instructions to Reviewers have also been updated to clarify these points.
If you have questions about addressing this review criterion within your proposal, contact Rebecca Terns in Proposal Enhancement at firstname.lastname@example.org.