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Announcements Find Funding Large Grant Opportunities

This NOFO solicits applications for the continued development and sustainment of high value informatics research resources to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology.

Amount: $4,560,000

Due Date: 10/19/2026

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Announcements Find Funding Large Grant Opportunities

This program solicits applications for research on developing a comprehensive and cohesive understanding of cancer metastasis. Each MetNet Center should propose an overarching scientific theme that will be pursued through two or three scientific inter- and multidisciplinary basic research projects. Studies on all types of cancer are welcome, including rare and pediatric metastatic cancers. Proposed research is expected to advance our understanding towards a more comprehensive appreciation of metastasis as a whole body, systems-level problem.

Amount: $9,880,000

Due Date: 08/25/2026

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Announcements Find Funding Large Grant Opportunities

The purpose of this notice of funding opportunity (NOFO) is to establish a Center that educates and mentors researchers in formal product development for new substance use disorder (SUD) pharmacotherapeutics and to advance the best concepts through initial experiments via technical and financial support.

Amount: Unspecified

Due Date: 09/30/2026

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Announcements Find Funding Large Grant Opportunities

This program intends to fund high-impact research that bridges the gap between research, practice and policy by building real-world evidence on how interventions, clinical practices/guidelines, or policies can be deployed to targeted populations at the appropriate time. In order to meet this intent, the mechanism supports health services research approaches.

Amount: $4,000,000

Due Date: 09/24/2026 (LOI); 10/15/2026 (Full Proposal)

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Announcements Find Funding Large Grant Opportunities

This NOFO invites applications for the enhancement and dissemination of emerging, user-friendly informatics technologies that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis is on uniqueness and potential impact on cancer research.

Amount: $4,560,000

Due Date: 10/19/2026

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Announcements Find Funding Large Grant Opportunities

This program supports clinical trials with the potential to have a significant impact on psychological health conditions and/or traumatic brain injury (TBI) through clinical applications, including health care products, technologies and/or practice guidelines.

Amount: $2,100,000 (Level 1); $4,100,000 (Level 2)

Due Date: 07/13/2026 (Pre-Applications); 10/15/2026 (Full Proposals)

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Announcements Find Funding Large Grant Opportunities

This program supports research on STEM education in one or more of three research areas: STEM learning and learning environments, broadening participation in STEM, and STEM workforce development.

Amount: $500,000 (Level I); $1,500,000 (Level II); $2,500,000 (Level III)

Due Date: 10/01/2026

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Announcements Find Funding Large Grant Opportunities

This NOFO invites applications from eligible organizations to establish a Data Coordination and Integration Center (DCIC) which will support the coordination and integration of data from both the HEAL INTERACT program and progressively facilitate broader integration of related musculoskeletal datasets and programs. The Center will lead efforts for managing and integrating complex pain-associated data types and information from the INTERACT Consortium and progressively related datasets. It will also establish a web-accessible information system and disseminate datasets that can facilitate hypothesis generation and be widely used throughout the research community. 

Amount: $4,000,000

Due Date: 10/06/2026

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Announcements Find Funding Large Grant Opportunities

This award supports the rapid implementation of clinical trials with the potential to have significant impact on the treatment and management of a disease or condition addressed in one of the congressionally directed FY26 PRMRP topic areas and FY26 PRMRP strategic goals.

Amount: $800,000 (Planning); $6M (Level 1); $10M (Level 2); $20M (Level 3)

Due Date: 07/23/2026 (Pre-Proposals); 09/22/2026 (Invited Full Proposals)

This award supports the rapid implementation of clinical trials with the potential to have significant impact on the treatment and management of a disease or condition addressed in one of the congressionally directed FY26 PRMRP topic areas and FY26 PRMRP strategic goals.

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Announcements Find Funding Large Grant Opportunities

This NOFO invites applications which include at least two related, synergistic Research Projects that share a common central theme, focus, and/or overall objective; an Administrative Core; and optional Scientific Core(s). Applications must address scientific areas relevant to the NIAID mission.

Amount: Unspecified

Due Date: 09/26/2026

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