Michael Mispagel Human and Animal Cancer Research Fund Seed Grant

The University of Georgia, College of Veterinary Medicine is pleased to announce a call for proposals for new seed grant funding opportunity available to researchers across the University of Georgia. The Michael Mispagel Human and Animal Cancer Research Fund will provide seed funding of $10,000 for one year to support basic and/or applied research projects that aim to elucidate the mechanisms of oncogenesis of, and develop immunotherapies for, sarcomas and similar soft tissue tumors. The purpose of the grant is to encourage collaborative studies among basic scientists, technology developers, and clinical oncologists to generate novel platform technologies in bioinformatics, animal models, immunological or tumor profiling instrumentation, and other relevant technologies that will ultimately allow clinician scientists to gain insight into the mechanisms of action of existing and potential immunotherapies and better predict their efficacies.

Competitive applications will propose creative approaches toward a better understanding of tumor formation and metastasis as well as innovative technologies with the potential to impact cancer immunotherapy for both human and animal patients. Examples of relevant studies may include, but are not limited to the following.

  • Bioinformatics methods that facilitate collection and analysis of large sets of patient-derived data.
  • Methods that improve profiling of tumors to inform therapeutic strategies.
  • In vitro tissue culture systems and in vivo animal models that can be used to elucidate the interactions between primary tumor cells and the immune system.

Letter of Intent and Proposal Format and Requirements

All UGA faculty are eligible to apply. Letters of intent are due to Dr. Jennifer Smith-Garvin at jgarvin@uga.eduno later than February 18th. The letter should be no more than 1 page and include a brief overview of the proposed project including research objectives and potential impact for cancer research, diagnoses and treatment. Letters should also include a list of investigators, their affiliations and email addresses. Select applicants invited to submit a full proposal will be notified by February 25th and must submit the full application by April 2nd, 2019.

Email Dr. Smith-Garvin at jgarvin@uga.edu with any questions.

Full RFP

The University of Georgia, College of Veterinary Medicine is pleased to announce a call for proposals for new seed grant funding opportunity available to researchers across the University of Georgia. The Michael Mispagel Human and Animal Cancer Research Fund will provide seed funding of $10,000 for one year to support basic and/or applied research projects that aim to elucidate the mechanisms of oncogenesis of, and develop immunotherapies for, sarcomas and similar soft tissue tumors.  The purpose of the grant is to encourage collaborative studies among basic scientists, technology developers, and clinical oncologists to generate novel platform technologies in bioinformatics, animal models, immunological or tumor profiling instrumentation, and other relevant technologies that will ultimately allow clinician scientists to gain insight into the mechanisms of action of existing and potential immunotherapies and better predict their efficacies.

Competitive applications will propose creative approaches toward a better understanding of tumor formation and metastasis as well as innovative technologies with the potential to impact cancer immunotherapy for both human and animal patients.  Examples of relevant studies may include, but are not limited to the following.

  • Bioinformatics methods that facilitate collection and analysis of large sets of patient-derived data.
  • Methods that improve profiling of tumors to inform therapeutic strategies.
  • In vitro tissue culture systems and in vivo animal models that can be used to elucidate the interactions between primary tumor cells and the immune system.

Letter of Intent and Proposal Format and Requirements

All UGA faculty are eligible to apply. Letters of intent are due to Dr. Jennifer Smith-Garvin at jgarvin@uga.edu no later than February 18th.  The letter should be no more than 1 page and include a brief overview of the proposed project including research objectives and potential impact for cancer research, diagnoses and treatment.  Letters should also include a list of investigators, their affiliations and email addresses.  Select applicants invited to submit a full proposal will be notified by February 25th and must submit the full application by April 2nd, 2019.

Full Proposal Format and Requirements

Applications should be submitted as a single PDF. Single-spaced, minimum 11pt font, 0.75 inch margins.

  1. Cover Page (maximum 1 page)
    1. Title of Proposed Study
    1. Name, affiliation, email address for Primary Investigator and co-investigators
    1. Funding amount requested
    1. IACUC approval number when applicable
    1. If client-owned animals will be included, provide a statement indicating the proposal has been approved by the Clinical Research Committee or a statement indicating that PI is aware that the proposal must be approved by the CRC before awards can be dispersed.
    1. Signature of PI and co-
  1. Abstract (maximum 300 words)

Abstracts should briefly explain the hypothesis, the approach and the relevance of the work to feline health.

  1. Study proposal (maximum 4 pages)
    1. Introduction – should include background and emphasize the significance and potential impact of the proposed study on cancer research, diagnosis and treatment.
    1. Research Strategy – In the first paragraph clearly state the hypothesis and individual aims/objectives of the project. The remainder of the section should clearly and precisely describe the rationale and experimental design for each aim/objective and include any supporting preliminary data. Descriptions of experimental design should include animal use justification, anticipated results and statistical analyses as well as potential pitfalls and alternative approaches.
  1. Budget (1page)

            itemized budget for use of requested funds (up to $10,000) and anticipated plan for securing further       funding to continue the project.

  • References (maximum 2 pages)
  • Biosketch (multiple pages as needed):NIH-style biosketch for each investigator.

Review Process

Proposals will be reviewed by staff from the College of Veterinary Medicine, Office for Research and Graduate Affairs and select members of the College of Veterinary Medicine Research Committee.  Other individuals may be consulted as needed.  Applicants will be notified of decisions in late January and funds will be made available soon after.

Progress Reports

After 1 year, funding recipients should send a progress report outlining the research outcomes and future directions to jgarvin@uga.edu

Publication Acknowledgements

Any publications resulting from funding or partial funding by the Michael Mispagel Human and Animal Research Fund should acknowledge that funding was received.

The research in this article was supported by a grant funded by the Michael Mispagel Human Animal Research Fund at the University of Georgia, College of Veterinary Medicine.