{"id":38205,"date":"2018-02-26T16:20:44","date_gmt":"2018-02-26T21:20:44","guid":{"rendered":"https:\/\/research.uga.edu\/news\/?p=38205"},"modified":"2021-07-20T08:59:18","modified_gmt":"2021-07-20T12:59:18","slug":"researcher-works-to-build-universal-flu-vaccine","status":"publish","type":"post","link":"https:\/\/research.uga.edu\/news\/researcher-works-to-build-universal-flu-vaccine\/","title":{"rendered":"Researcher works to build universal flu vaccine"},"content":{"rendered":"

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Every year, flu season comes around. And every year new vaccines are developed to combat it.<\/p>\n

Creating an annual flu vaccine involves a combination of researching current strains, identifying the disease\u2019s historical patterns, and predicting the worldwide movement of viruses. Educated guesswork plays a big role as well.<\/p>\n

It\u2019s an imperfect process.<\/p>\n

The variables can be maddening to overcome, and the logistics surrounding vaccine manufacturing can be unforgiving. Choose wisely and the flu vaccine can be quite effective. Choose poorly and a disease with the potential to kill tens of thousands in the U.S. alone could run rampant.<\/p>\n

There has to be a better way. Ted Ross is committed to finding it.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column css=”.vc_custom_1567706852217{background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_raw_html el_class=”container”]JTNDaWZyYW1lJTIwd2lkdGglM0QlMjIxMDAlMjUlMjIlMjBoZWlnaHQlM0QlMjI3MDAlMjIlMjBzcmMlM0QlMjJodHRwcyUzQSUyRiUyRnd3dy55b3V0dWJlLmNvbSUyRmVtYmVkJTJGVktOcjRyN3V6OHclM0ZyZWwlM0QwJTIyJTIwdGl0bGUlM0QlMjJZb3VUdWJlJTIwdmlkZW8lMjBwbGF5ZXIlMjIlMjBmcmFtZWJvcmRlciUzRCUyMjAlMjIlMjBhbGxvdyUzRCUyMmFjY2VsZXJvbWV0ZXIlM0IlMjBhdXRvcGxheSUzQiUyMGNsaXBib2FyZC13cml0ZSUzQiUyMGVuY3J5cHRlZC1tZWRpYSUzQiUyMGd5cm9zY29wZSUzQiUyMHBpY3R1cmUtaW4tcGljdHVyZSUyMiUyMGFsbG93ZnVsbHNjcmVlbiUzRSUzQyUyRmlmcmFtZSUzRQ==[\/vc_raw_html][vc_column_text el_class=”container image-caption”]<\/p>\n

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Ted Ross, the Georgia Research Alliance Eminent Scholar of Infectious Diseases and director of the Center for Vaccines and Immunology, is developing a new universal flu vaccine that could change the way we fight influenza.<\/p>\n<\/div>\n<\/div>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text el_class=”text-container”]The Georgia Research Alliance Eminent Scholar in Infectious Diseases is getting a boost to do just that, with a new grant from the National Institutes of Health that is worth up to\u00a0$130 million<\/a>\u00a0over seven years to develop a new, more advanced influenza vaccine designed to protect against multiple strains of influenza virus in a single dose. UGA faculty will lead one of NIH\u2019s new prestigious Collaborative Influenza Vaccine Innovation Centers and collaborate with teams from 14 other universities and research institutes to create and test new vaccines that may one day replace seasonal vaccines administered every year during flu season.<\/p>\n

\u201cHow do you deal with a vaccine if you are constantly playing catch up?\u201d asks Ross, who also serves as director of the University of Georgia Center for Vaccines and Immunology. One of the country\u2019s leading infectious disease researchers, Ross came to UGA in 2015 to lead its newly established Center for Vaccines and Immunology.<\/p>\n

\u201cWe need to come up with a strategy where we will always have a vaccine on the shelf, ready to use, no matter what version of the flu came along,\u201d he says. \u201cBut how do we make vaccines against future, variant strains that don\u2019t yet exist?\u201d<\/p>\n

The diseases we\u2019ve defeated through vaccines\u2014polio, smallpox and the like\u2014have one thing in common: limited or no variety in their strains. That\u2019s why they can be eliminated with a single inoculation.<\/p>\n

Influenza is different. It has many strains, and those strains are constantly evolving. Sometimes they evolve so quickly that a vaccine developed in February is obsolete by the time flu season starts in October.<\/p>\n

\u201cWhat we need to do is target the major subtypes of influenza and come up with a vaccine that recognizes multiple versions,\u201d Ross says. \u201cIt may take more than one type of vaccine, but at least we would be broadly protected against the viruses that have shown pandemic potential.\u201d[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_single_image image=”38212″ img_size=”full” add_caption=”yes” el_class=”container”][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text el_class=”text-container”]Ross\u2019s goal is to create what some call a \u201cuniversal vaccine\u201d for flu. That makes for easy shorthand, but Ross is quick to clarify that even if a vaccine can be discovered to wipe out influenza, it wouldn\u2019t be a single compound that\u2019s given to everyone.<\/p>\n

Instead, Dr. Ross\u2019s approach is to develop a collection of vaccines. The type of protection administered to specific patients would be based on a variety of factors including geography, age, medical history and other factors. Rather than a \u201cuniversal\u201d vaccine, Ross prefers the term \u201cbroadly protected.\u201d[\/vc_column_text][\/vc_column][\/vc_row][vc_section css=”.vc_custom_1567710408463{background-color: #e4ddc7 !important;}” el_class=”fw-polygon”][vc_row equal_height=”yes” bg_type=”bg_color”][vc_column width=”1\/2″ css=”.vc_custom_1567710326062{margin-top: 0px !important;margin-bottom: 0px !important;border-bottom-width: 0px !important;padding-top: 0px !important;}” el_class=”polygon-wrapper”][vc_raw_html el_class=”polygon” css=”.vc_custom_1624375177245{background-image: url(https:\/\/research.uga.edu\/news\/wp-content\/uploads\/sites\/19\/2021\/06\/TedRossFeatured2.jpg?id=38208) !important;}”]JTNDJTIxLS1sZWF2ZSUyMHRoaXMlMjBlbXB0eS0tJTNF[\/vc_raw_html][\/vc_column][vc_column width=”1\/2″ el_class=”polygon-content”][vc_column_text el_class=”testimonial”]“How do you deal with a vaccine if you are constantly playing catch up? We need to come up with a strategy where we will always have a vaccine on the shelf, ready to use, no matter what version of the flu came along.”<\/strong><\/em>[\/vc_column_text][vc_column_text el_class=”credit”]<\/p>\n

\u2013 Ted Ross, GRA Eminent Scholar of Infectious Disease, College of Veterinary Medicine<\/p>\n

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Ted Ross<\/h3>\n

GRA Eminent Scholar of Infectious Disease
\nCollege of Veterinary Medicine
\nDirector, Center for Vaccines and Immunology<\/p>\n

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Help Battle Deadly Diseases<\/h2>\n

Donate to the Center for Vaccines and Immunology<\/p>\n

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